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Aeterna Zentaris Inc., a specialty biopharmaceutical company, engages in developing and commercializing therapeutics and diagnostic tests. Its lead product is Macrilen (macimorelin), an orally available peptidomimetic ghrelin receptor (GHSR-1a) agonist that stimulates the secretion of growth hormone by binding to the GHSR-1a for the diagnosis of adult growth hormone deficiency and childhood-onset growth hormone deficiency, as well as oncology indications; and AEZS-150, a delayed clearance parathyroid hormonefusion polypeptide that is in preclinical trail for the treatment of hypoparathyroidism in adults. Aeterna Zentaris Inc. has a license agreement with University of Wuerzburg to research, develop, manufacture, and sell a potential COVID-19 vaccine; development, manufacture, and commercialization of the treatment for neuromyelitis optica spectrum disorder; and for pre-clinical development towards the potential treatment of Parkinson's disease. It also has a license agreement with Consilient Health Ltd. and NK MEDITECH Ltd. for the development and commercialization of macimorelin in the Republic of Korea; a distribution and commercialization agreement with Er-Kim Pharmaceuticals Bulgaria EOOD for the commercialization of macimorelin for the diagnosis of growth hormone deficiency in children and adults in Turkey and some non-European Union Balkan countries; as well as The University of Sheffield, the United Kingdom for the research, development, manufacture, and commercialization of parathyroid hormone fusion polypeptides for the treatment of primary hypoparathyroidism. Aeterna Zentaris Inc. was incorporated in 1990 and is headquartered in Summerville, South Carolina.
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| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Income before tax | -22.73M | -8.48M | -4.72M | -6.23M | 9.64M |
| Net income | -30.20M | -8.37M | -5.12M | -6.04M | 4.19M |
| Selling general administrative | 8.23M | 5.92M | 4.76M | 6.62M | 8.89M |
| Selling and marketing expenses | 8.23M | 1.35M | 1.13M | 1.21M | 3.11M |
| Gross profit | 5.48M | 5.17M | 1.33M | 0.12M | 24.78M |
| Reconciled depreciation | 0.14M | 0.14M | 0.23M | 0.32M | 0.06M |
| Ebit | -15.25M | -8.67M | -6.06M | -9.54M | 9.64M |
| Ebitda | -7.65M | -8.53M | -7.91M | -9.23M | 9.70M |
| Depreciation and amortization | 7.61M | 0.14M | -1.84M | 0.32M | 0.06M |
| Operating income | -15.25M | -8.67M | -6.06M | -9.54M | 9.84M |
| Other operating expenses | 20.89M | 13.93M | 9.72M | 10.08M | 17.04M |
| Interest expense | 0.00M | 0.02M | 3.42M | 0.59M | 0.00M |
| Tax provision | 0.00M | -0.11M | 0.40M | -0.19M | 5.45M |
| Interest income | 0.88M | 0.21M | 1.70M | 4.61M | 0.92M |
| Net interest income | -0.00M | -0.02M | -0.74M | -0.59M | 0.28M |
| Income tax expense | 7.47M | -0.11M | 0.40M | -0.19M | 5.45M |
| Total revenue | 5.64M | 5.26M | 3.65M | 0.53M | 26.88M |
| Total operating expenses | 20.74M | 13.84M | 7.40M | 9.67M | 14.94M |
| Cost of revenue | 0.16M | 0.09M | 2.32M | 0.41M | 2.10M |
| Total other income expense net | -7.47M | 0.19M | 1.34M | 3.31M | -0.20M |
| Net income from continuing ops | -22.73M | -8.37M | -5.12M | -6.04M | 4.19M |
| Net income applicable to common shares | -22.73M | -8.37M | -5.12M | -6.04M | 4.19M |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Total assets | 56.03M | 80.10M | 37.28M | 19.98M | 25.01M |
| Intangible assets | 0.00M | 0.62M | 0.06M | 0.04M | 0.06M |
| Other current assets | 2.49M | 1.77M | 0.87M | 1.21M | 1.21M |
| Total liab | 20.25M | 27.12M | 24.07M | 22.44M | 23.10M |
| Total stockholder equity | 35.78M | 52.99M | 13.21M | -2.46M | 1.91M |
| Other current liab | 1.94M | 1.89M | 3.00M | 2.93M | 2.57M |
| Common stock | 293.41M | 293.41M | 235.01M | 224.53M | 222.34M |
| Capital stock | 293.41M | 293.41M | 235.01M | 224.53M | 222.34M |
| Retained earnings | -352.08M | -334.62M | -322.66M | -316.89M | -309.78M |
| Other liab | - | 19.32M | 19.00M | 16.53M | 17.51M |
| Good will | 0.00M | 8.13M | 8.81M | 8.05M | 8.21M |
| Other assets | 0.32M | 0.34M | 0.34M | 0.36M | 0.42M |
| Cash | 50.61M | 65.30M | 24.27M | 7.84M | 14.51M |
| Cash and equivalents | 0.00M | 9.70M | 0.35M | 7.84M | 14.51M |
| Total current liabilities | 7.04M | 7.77M | 5.01M | 5.66M | 5.60M |
| Current deferred revenue | 2.95M | 4.82M | 2.19M | 0.99M | 0.07M |
| Net debt | -50.43M | -65.14M | -24.09M | -6.93M | -14.51M |
| Short term debt | 0.11M | 0.13M | 0.14M | 0.65M | 0.00M |
| Short long term debt total | 0.18M | 0.16M | 0.18M | 0.90M | - |
| Other stockholder equity | 95.42M | 94.87M | 101.91M | 89.81M | 89.34M |
| Property plant equipment | 0.22M | 0.19M | 0.18M | 0.62M | 0.07M |
| Total current assets | 55.49M | 70.82M | 27.89M | 10.91M | 16.26M |
| Net tangible assets | - | 44.23M | 4.34M | -10.55M | -6.37M |
| Net receivables | 2.16M | 3.67M | 1.68M | 0.66M | 0.29M |
| Inventory | 0.23M | 0.07M | 0.02M | 1.20M | 0.24M |
| Accounts payable | 2.04M | 0.93M | 1.19M | 1.09M | 1.28M |
| Accumulated other comprehensive income | -0.97M | -0.68M | -1.04M | 0.09M | 0.01M |
| Common stock total equity | - | - | 235.01M | 224.53M | 222.34M |
| Non currrent assets other | 0.32M | 0.34M | 0.34M | 0.36M | 0.42M |
| Non current assets total | 0.54M | 9.28M | 9.39M | 9.07M | 8.76M |
| Capital lease obligations | 0.18M | 0.16M | 0.18M | 0.90M | - |
| Long term debt total | 0.07M | 0.03M | 0.05M | 0.26M | 0.00M |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Investments | -0.01M | -0.66M | 0.06M | 0.05M | -0.04M |
| Change to liabilities | - | 3.64M | 3.08M | 0.13M | -0.19M |
| Total cashflows from investing activities | -0.01M | -0.66M | 0.06M | 0.05M | -0.04M |
| Net borrowings | - | -0.13M | -0.27M | -0.61M | -0.61M |
| Total cash from financing activities | -0.12M | 51.04M | 20.47M | 3.89M | 3.89M |
| Change to operating activities | - | -1.10M | -1.23M | -1.04M | -1.85M |
| Net income | -22.73M | -8.37M | -5.12M | -6.04M | 4.19M |
| Change in cash | -14.69M | 41.03M | 16.43M | -6.67M | 6.73M |
| Begin period cash flow | 65.30M | 24.27M | 7.84M | 14.51M | 7.78M |
| End period cash flow | 50.61M | 65.30M | 24.27M | 7.84M | 14.51M |
| Total cash from operating activities | -13.68M | -8.58M | -4.13M | -10.72M | 6.83M |
| Issuance of capital stock | 0.00M | 34.20M | 23.50M | 4.99M | 0.00M |
| Depreciation | 0.14M | 0.14M | 0.23M | 0.32M | 0.06M |
| Other cashflows from investing activities | -0.00M | -0.02M | 0.05M | 0.05M | -0.05M |
| Change to inventory | -0.16M | -0.06M | 1.18M | -0.97M | 0.31M |
| Change to account receivables | - | 0.12M | -1.33M | -0.73M | -0.10M |
| Sale purchase of stock | 0.00M | 54.29M | 23.50M | 5.30M | 0.00M |
| Other cashflows from financing activities | 0.02M | 16.96M | -2.77M | -0.48M | -0.04M |
| Change to netincome | - | -2.86M | -2.38M | -3.10M | 2.73M |
| Capital expenditures | 0.01M | 0.64M | 0.03M | 0.03M | 0.01M |
| Change in working capital | 0.60M | 2.50M | 2.40M | -2.44M | -0.15M |
| Stock based compensation | 0.54M | 0.31M | 0.06M | 0.79M | 0.57M |
| Other non cash items | 7.76M | -3.17M | -1.71M | -3.35M | -1.32M |
| Free cash flow | -13.69M | -9.22M | -4.13M | -10.72M | 6.82M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(CAD) |
Price
(CAD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| EPRX Eupraxia Pharmaceuticals Inc |
-0.22 2.32% |
9.26 | - | - | - | 8.45 | - | -3.88 |
| FRX Fennec Pharmaceuticals Inc |
-1.17 8.09% |
13.29 | - | 21.01 | 6.95 | 6.35 | 4.25 | 20.27 |
| MSCL Satellos Bioscience Inc. |
-0.40 4.30% |
8.91 | - | - | - | 5.85 | - | 6.47 |
| HBP Helix BioPharma Corp. |
-0.02 2.17% |
0.90 | - | 3.87 | 4263.36 | 9.74 | 4422.35 | -6.36 |
Aeterna Zentaris Inc., a specialty biopharmaceutical company, engages in developing and commercializing therapeutics and diagnostic tests. Its lead product is Macrilen (macimorelin), an orally available peptidomimetic ghrelin receptor (GHSR-1a) agonist that stimulates the secretion of growth hormone by binding to the GHSR-1a for the diagnosis of adult growth hormone deficiency and childhood-onset growth hormone deficiency, as well as oncology indications; and AEZS-150, a delayed clearance parathyroid hormonefusion polypeptide that is in preclinical trail for the treatment of hypoparathyroidism in adults. Aeterna Zentaris Inc. has a license agreement with University of Wuerzburg to research, develop, manufacture, and sell a potential COVID-19 vaccine; development, manufacture, and commercialization of the treatment for neuromyelitis optica spectrum disorder; and for pre-clinical development towards the potential treatment of Parkinson's disease. It also has a license agreement with Consilient Health Ltd. and NK MEDITECH Ltd. for the development and commercialization of macimorelin in the Republic of Korea; a distribution and commercialization agreement with Er-Kim Pharmaceuticals Bulgaria EOOD for the commercialization of macimorelin for the diagnosis of growth hormone deficiency in children and adults in Turkey and some non-European Union Balkan countries; as well as The University of Sheffield, the United Kingdom for the research, development, manufacture, and commercialization of parathyroid hormone fusion polypeptides for the treatment of primary hypoparathyroidism. Aeterna Zentaris Inc. was incorporated in 1990 and is headquartered in Summerville, South Carolina.
| Name | Title | Year Born |
|---|---|---|
| Dr. Klaus Paulini Ph.D. | Pres, CEO & Exec. Director | NA |
| Dr. Nicola Ammer M.D. | Chief Medical Officer & Sr. VP of Clinical Devel. | NA |
| Dr. Matthias Gerlach | Sr. VP Manufacturing & Supply Chain | NA |
| Mr. Giuliano La Fratta | Sr. VP of Fin. & CFO | NA |
| Dr. Michael Teifel | Sr. VP of Non-Clinical Devel. & Chief Scientific Officer | NA |
| Dr. Eckhard G. Guenther Ph.D. | Sr. VP of Bus. Devel. & Alliance Management and MD of AEZS Germany | NA |
| Ms. Amélie Métivier | Assistant Sec. | NA |
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