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Artiva Biotherapeutics, Inc., a clinical-stage biotechnology company, focuses on developing natural killer (NK) cell-based therapies for patients suffering from autoimmune diseases and cancers. The company's lead product candidate is AB-101, an off-the-shelf NK cell therapy for patients with autoimmune diseases and cancers, such as lupus nephritis, rheumatoid arthritis, pemphigus vulgaris, the anti-neutrophil cytoplasmic antibody-associated vasculitis subtypes granulomatosis with polyangiitis/microscopic polyangiitis, systemic lupus erythematosus, and B-cell-non-Hodgkin lymphoma. It also develops AB-201, an allogeneic anti- human epidermal growth factor receptor 2 chimeric antigen receptor (CAR)-NK cell product candidate; and AB-205, an allogeneic anti-CD5 CAR-NK cell product candidate. The company was incorporated in 2019 and is headquartered in San Diego, California.
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Artiva Biotherapeutics is a clinical-stage biotechnology company developing allogeneic natural killer (NK) and CAR-NK cell therapies for hematologic malignancies and selected solid tumors. Long-term growth drivers include clinical trial outcomes, scalable manufacturing to enable off-the-shelf products, and collaborations or regulatory approvals that may broaden indications and support commercialization.
Principal investment risks are high clinical and regulatory uncertainty, substantial financing and manufacturing scale-up requirements, and intense competition within the cell therapy and immuno-oncology sectors.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 |
|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly |
| Date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 |
| Income before tax | -27.62M | -58.34M | -71.83M | -17.99M |
| Net income | -27.70M | -58.39M | -71.83M | -17.99M |
| Selling general administrative | 13.91M | 20.78M | 12.86M | 4.43M |
| Gross profit | 33.49M | 4.93M | 2.00M | - |
| Reconciled depreciation | 2.27M | 1.16M | 0.25M | 0.07M |
| Ebit | -30.67M | -59.83M | -71.83M | -17.79M |
| Ebitda | -28.41M | -58.67M | -71.58M | -17.72M |
| Depreciation and amortization | 2.27M | 1.16M | 0.25M | 0.07M |
| Operating income | -30.67M | -59.83M | -53.27M | -18.27M |
| Other operating expenses | 64.16M | 64.76M | 55.27M | 18.27M |
| Interest expense | - | - | 0.00M | 0.20M |
| Tax provision | 0.07M | 0.05M | - | - |
| Interest income | 2.54M | 1.29M | 0.00M | 0.00M |
| Net interest income | 2.54M | 1.29M | 0.00M | -0.20M |
| Income tax expense | 0.07M | 0.05M | -18.55M | 0.68M |
| Total revenue | 33.49M | 4.93M | 2.00M | 0.00M |
| Total operating expenses | 64.16M | 64.76M | 55.27M | 18.27M |
| Total other income expense net | 3.05M | 1.49M | -18.55M | 0.28M |
| Net income from continuing ops | -27.70M | -58.39M | -71.83M | -17.99M |
| Breakdown | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Total assets | 105.11M | 133.05M | 169.93M | 29.23M | - |
| Other current assets | 1.09M | 1.62M | 0.90M | 0.67M | - |
| Total liab | 267.13M | 273.75M | 258.78M | 50.80M | - |
| Total stockholder equity | -162.01M | -140.70M | -88.86M | -21.57M | - |
| Other current liab | 8.02M | 10.15M | 10.13M | 3.15M | - |
| Capital stock | 0.00M | 0.00M | 0.00M | 0.00M | - |
| Retained earnings | -181.31M | -152.59M | -93.80M | -21.98M | - |
| Other assets | - | 0.01M | - | - | - |
| Cash | 53.50M | 102.53M | 160.92M | 25.44M | - |
| Total current liabilities | 12.23M | 25.62M | 19.30M | 5.76M | - |
| Current deferred revenue | - | 10.89M | 7.29M | - | - |
| Net debt | -36.59M | -83.08M | -159.18M | -23.33M | 3.77M |
| Short term debt | 3.60M | 3.49M | 0.43M | 0.46M | - |
| Short long term debt total | 16.91M | 19.45M | 1.74M | 2.12M | - |
| Other stockholder equity | 18.99M | 11.89M | 4.95M | 0.41M | - |
| Total current assets | 79.82M | 104.67M | 162.29M | 26.11M | - |
| Short term investments | 23.47M | 0.00M | - | - | - |
| Net receivables | 1.76M | 0.53M | 0.47M | 0.00M | - |
| Long term debt | - | - | - | - | 5.64M |
| Accounts payable | 0.61M | 1.10M | 1.44M | 2.15M | - |
| Accumulated other comprehensive income | 0.31M | - | - | - | - |
| Non currrent assets other | 0.65M | 0.76M | 3.56M | 0.73M | - |
| Non current assets total | 25.29M | 28.37M | 7.64M | 3.13M | - |
| Capital lease obligations | 16.91M | 19.45M | 1.74M | 2.12M | - |
| Breakdown | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 |
|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly |
| Date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 |
| Investments | -25.98M | -6.30M | -1.72M | -0.28M |
| Total cash from financing activities | 24.39M | -1.26M | 152.75M | 37.40M |
| Net income | -28.72M | -58.79M | -71.83M | -17.99M |
| Change in cash | -49.01M | -58.39M | 135.73M | 23.57M |
| Begin period cash flow | 102.78M | 161.17M | 25.44M | 1.87M |
| End period cash flow | 53.76M | 102.78M | 161.17M | 25.44M |
| Total cash from operating activities | -47.43M | -50.83M | -15.30M | -13.54M |
| Issuance of capital stock | - | - | 154.61M | 34.85M |
| Depreciation | 2.27M | 1.16M | 0.25M | 0.07M |
| Change to account receivables | -0.51M | -0.06M | -0.47M | 0.00M |
| Sale purchase of stock | -0.01M | -0.01M | - | - |
| Other cashflows from financing activities | 24.40M | -1.26M | 152.75M | 34.18M |
| Capital expenditures | 3.26M | 6.30M | 1.72M | 0.28M |
| Change in working capital | -28.28M | -3.87M | 33.41M | 4.36M |
| Stock based compensation | 7.05M | 6.58M | 4.31M | 0.30M |
| Other non cash items | 0.25M | - | 18.55M | -0.28M |
| Free cash flow | -50.69M | -57.13M | -17.03M | -13.82M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
|---|---|---|---|---|---|---|---|
| ARTV Artiva Biotherapeutics, Inc. Common Stock |
0.07 1.69% |
4.22 | - | - | 109.91 | 1.43 | 59.57 |
| NVO Novo Nordisk A/S |
1.09 2.72% |
41.41 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 |
| VRTX Vertex Pharmaceuticals Inc |
3.78 0.69% |
550.87 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 |
| REGN Regeneron Pharmaceuticals Inc |
15.61 1.73% |
919.96 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 |
Artiva Biotherapeutics, Inc., a clinical-stage biotechnology company, focuses on developing natural killer (NK) cell-based therapies for patients suffering from autoimmune diseases and cancers. The company's lead product candidate is AB-101, an off-the-shelf NK cell therapy for patients with autoimmune diseases and cancers, such as lupus nephritis, rheumatoid arthritis, pemphigus vulgaris, the anti-neutrophil cytoplasmic antibody-associated vasculitis subtypes granulomatosis with polyangiitis/microscopic polyangiitis, systemic lupus erythematosus, and B-cell-non-Hodgkin lymphoma. It also develops AB-201, an allogeneic anti- human epidermal growth factor receptor 2 chimeric antigen receptor (CAR)-NK cell product candidate; and AB-205, an allogeneic anti-CD5 CAR-NK cell product candidate. The company was incorporated in 2019 and is headquartered in San Diego, California.
| Name | Title | Year Born |
|---|---|---|
| Dr. Fred Aslan M.D. | President, CEO & Director | 1975 |
| Dr. Peter Flynn Ph.D. | Co-Founder & Strategic Advisor | 1974 |
| Ms. Jennifer Kinsbruner Bush Esq., J.D. | Executive VP, COO, Chief Legal Officer, Corporate Secretary & Compliance Officer | 1975 |
| Mr. Christopher P. Horan | Chief Technical Operations Officer | 1967 |
| Ms. Neha Krishnamohan | CFO & Executive VP of Corporate Development | 1987 |
| Dr. Thorsten Graef M.D., Ph.D. | Chief Medical Officer | 1976 |
| Dr. Heather Raymon Ph.D. | Senior Vice President of Research & Early Development | 1964 |
| Mr. Javier Coindreau M.D. | Senior VP of Medical Affairs | NA |
| Dr. David Moriarty Ph.D. | Senior VP of Clinical Operations | NA |
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