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Clene Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics. The company's lead drug candidate is CNM-Au8, which is being studied in various clinical trials, including a completed Phase 2 platform trial to evaluate the safety and efficacy of CNM-Au8 in patients with amyotrophic lateral sclerosis (ALS); completed Phase 2 proof of concept clinical trial in patients with early symptomatic ALS; completed two open-label investigator blinded Phase 2 clinical trials on the brain's energy metabolites; completed Phase 2 clinical trial for the treatment of visual pathway deficits in chronic optic neuropathy for remyelination in stable relapsing Multiple Sclerosis; and a second Phase 2 clinical trial for the treatment of patients with Parkinson's Diseases. It develops CNM-AgZn17, a gel polymer suspension of silver and zinc ions that is being developed for the treatment of infectious diseases and to support wound healing; and CNM-ZnAg, a broad-spectrum antiviral and antibacterial agent to treat infection disease and to provide immune support for symptom resolution. In addition, the company markets and distributes dietary supplements comprising rMetx, an aqueous zinc-silver ion dietary supplement; and KHC46, an aqueous gold dietary supplement of very low-concentration Au nanoparticles. Clene Inc. is headquartered in Salt Lake City, Utah.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
Clene Inc (NASDAQ: CLNN) is a clinical-stage biotechnology company developing experimental therapeutics for neurological and related conditions through a pipeline of drug candidates. Investors may find the company attractive because successful clinical outcomes, licensing or partnership deals, and expansion into large neurology markets could support future revenue and value creation.
Principal risks include clinical and regulatory setbacks, high cash burn with likely need for additional financing, competitive pressures from established developers, and execution risk in advancing trials and commercializing products.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -26.17M | -39.40M | -49.50M | -29.92M | -10.17M |
| Net income | -26.17M | -39.40M | -49.50M | -15.28M | -9.74M |
| Selling general administrative | 9.23M | 13.31M | 14.42M | 16.94M | 18.81M |
| Selling and marketing expenses | - | 1.03M | 1.05M | - | - |
| Gross profit | 0.16M | 0.27M | 0.53M | 0.45M | 0.43M |
| Reconciled depreciation | 1.50M | 1.65M | 1.59M | 1.02M | 0.95M |
| Ebit | -23.08M | -35.34M | -44.95M | -45.33M | -45.28M |
| Ebitda | -21.59M | -33.69M | -43.24M | -45.07M | -47.52M |
| Depreciation and amortization | 1.50M | 1.65M | 1.71M | 0.26M | -2.24M |
| Non operating income net other | - | - | - | 21.79M | 40.68M |
| Operating income | -23.08M | -33.09M | -40.54M | -45.33M | -45.28M |
| Other operating expenses | 23.28M | 33.44M | 41.19M | 45.80M | 46.00M |
| Interest expense | 2.68M | 4.06M | 4.56M | 3.30M | 0.87M |
| Tax provision | 0.00M | 0.00M | 0.00M | 0.00M | -0.43M |
| Interest income | 0.22M | 0.86M | 1.39M | - | - |
| Net interest income | -3.47M | -3.96M | -4.56M | -4.07M | -4.05M |
| Income tax expense | - | - | 1.54M | -14.64M | -0.43M |
| Total revenue | 0.20M | 0.34M | 0.65M | 0.47M | 0.72M |
| Total operating expenses | 23.24M | 33.37M | 41.07M | 45.78M | 45.71M |
| Cost of revenue | 0.04M | 0.07M | 0.12M | 0.03M | 0.29M |
| Total other income expense net | -3.09M | -6.31M | -8.96M | 15.41M | 35.11M |
| Net income from continuing ops | -26.17M | -39.40M | -40.38M | -29.92M | -9.74M |
| Net income applicable to common shares | - | - | - | -29.92M | -9.74M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 18.13M | 27.34M | 52.34M | 44.49M | 63.06M |
| Other current assets | 3.75M | 3.54M | 2.48M | 5.65M | 0.17M |
| Total liab | 35.72M | 36.19M | 38.95M | 41.26M | 50.47M |
| Total stockholder equity | -17.59M | -8.86M | 13.39M | 3.24M | 12.60M |
| Deferred long term liab | - | - | - | - | 18.10M |
| Other current liab | 5.00M | 5.10M | 3.72M | 3.86M | 3.61M |
| Common stock | 0.00M | 0.00M | 0.01M | 0.01M | 0.01M |
| Capital stock | 0.00M | 0.00M | 0.01M | 0.01M | 0.01M |
| Retained earnings | -308.30M | -282.12M | -242.72M | -193.22M | -163.30M |
| Other liab | - | - | - | 2.56M | 20.89M |
| Other assets | - | - | - | 0.06M | 0.06M |
| Cash | 5.19M | 12.15M | 28.82M | 18.33M | 50.29M |
| Total current liabilities | 10.78M | 10.29M | 25.33M | 13.86M | 6.03M |
| Current deferred revenue | - | 2.67M | 0.00M | - | - |
| Net debt | 16.48M | 8.69M | 3.34M | 13.49M | -26.25M |
| Short term debt | 4.88M | 1.28M | 20.11M | 6.98M | 0.49M |
| Short long term debt | 4.07M | 0.36M | 19.50M | 6.42M | - |
| Short long term debt total | 21.67M | 20.84M | 32.16M | 31.82M | 24.04M |
| Other stockholder equity | 290.53M | 273.19M | 255.90M | 196.25M | 175.66M |
| Property plant equipment | - | - | - | 15.24M | 5.17M |
| Total current assets | 8.98M | 16.16M | 38.85M | 29.20M | 54.58M |
| Net tangible assets | - | - | - | 3.24M | 12.60M |
| Short term investments | - | 0.00M | 6.18M | 4.98M | - |
| Net receivables | 0.00M | 0.39M | 1.34M | 0.19M | 1.61M |
| Long term debt | 13.54M | 15.43M | 7.15M | 19.25M | 14.48M |
| Inventory | 0.04M | 0.07M | 0.04M | 0.04M | 0.04M |
| Accounts payable | 0.89M | 1.24M | 1.50M | 3.01M | 1.92M |
| Accumulated other comprehensive income | 0.17M | 0.07M | 0.20M | 0.20M | 0.23M |
| Common stock total equity | - | - | - | 0.01M | 0.01M |
| Retained earnings total equity | - | - | - | -193.22M | -163.30M |
| Non currrent assets other | 0.06M | 0.06M | 0.06M | 0.06M | 0.06M |
| Non current assets total | 9.15M | 11.18M | 13.49M | 15.30M | 8.48M |
| Capital lease obligations | 4.06M | 5.06M | 5.51M | 6.15M | 4.96M |
| Long term debt total | - | - | - | - | 14.48M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | 0.00M | 6.32M | 7.00M | -4.99M | -1.33M |
| Change to liabilities | - | - | - | 0.54M | 2.33M |
| Total cashflows from investing activities | -0.04M | 6.32M | -1.50M | -10.16M | -1.33M |
| Net borrowings | 1.12M | -10.90M | 0.27M | 5.61M | 19.46M |
| Total cash from financing activities | 11.52M | -1.53M | 42.16M | 17.25M | 27.11M |
| Change to operating activities | - | - | - | -1.68M | 0.04M |
| Net income | -26.17M | -39.40M | -49.50M | -29.92M | -9.74M |
| Change in cash | -6.97M | -16.67M | 10.49M | -31.96M | -8.93M |
| Begin period cash flow | 12.21M | 28.88M | 18.39M | 50.35M | 59.27M |
| End period cash flow | 5.25M | 12.21M | 28.88M | 18.39M | 50.35M |
| Total cash from operating activities | -18.55M | -21.33M | -30.17M | -39.01M | -34.62M |
| Issuance of capital stock | 10.40M | 9.24M | 53.42M | 11.46M | 9.25M |
| Depreciation | 1.50M | 1.65M | 1.71M | 1.02M | 0.95M |
| Change to inventory | 0.03M | -0.03M | 0.01M | -0.00M | 0.15M |
| Change to account receivables | 0.06M | 0.08M | 0.05M | -0.14M | -0.03M |
| Sale purchase of stock | - | - | - | 11.77M | 7.80M |
| Other cashflows from financing activities | 1.50M | 0.12M | -0.20M | 5.92M | 18.02M |
| Change to netincome | - | - | - | 8.35M | 10.66M |
| Capital expenditures | 0.04M | 0.01M | 0.33M | 5.18M | 1.33M |
| Change receivables | - | - | - | -0.14M | -0.03M |
| Cash flows other operating | - | - | - | -19.72M | -38.96M |
| Exchange rate changes | - | - | - | - | -0.09M |
| Cash and cash equivalents changes | - | - | - | -31.93M | -8.93M |
| Change in working capital | -3.35M | 3.21M | -0.19M | -1.54M | 1.00M |
| Stock based compensation | 6.38M | 7.95M | 9.12M | 8.51M | 12.38M |
| Other non cash items | 3.10M | 5.26M | 8.70M | -17.09M | -37.59M |
| Free cash flow | -18.59M | -21.34M | -30.50M | -44.19M | -35.96M |
Sector: Consumer Defensive Industry: Packaged Foods
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| CLNN Clene Inc. |
-0.02 0.50% |
3.95 | - | - | 262.19 | 7.83 | 278.25 | -1.13 |
| NSRGF Nestle SA |
-1.51 1.43% |
104.11 | 26.86 | 18.76 | 3.13 | 7.10 | 3.81 | 21.70 |
| NSRGY Nestle SA ADR |
-2.25 2.11% |
104.18 | 26.82 | 18.66 | 3.18 | 7.07 | 3.81 | 21.70 |
| DANOY Danone PK |
-0.43 2.79% |
14.96 | 24.23 | 17.64 | 1.88 | 2.57 | 1.88 | 11.70 |
| GPDNF Danone S.A |
- -% |
75.84 | 20.30 | 14.75 | 1.65 | 2.24 | 1.76 | 10.92 |
Clene Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics. The company's lead drug candidate is CNM-Au8, which is being studied in various clinical trials, including a completed Phase 2 platform trial to evaluate the safety and efficacy of CNM-Au8 in patients with amyotrophic lateral sclerosis (ALS); completed Phase 2 proof of concept clinical trial in patients with early symptomatic ALS; completed two open-label investigator blinded Phase 2 clinical trials on the brain's energy metabolites; completed Phase 2 clinical trial for the treatment of visual pathway deficits in chronic optic neuropathy for remyelination in stable relapsing Multiple Sclerosis; and a second Phase 2 clinical trial for the treatment of patients with Parkinson's Diseases. It develops CNM-AgZn17, a gel polymer suspension of silver and zinc ions that is being developed for the treatment of infectious diseases and to support wound healing; and CNM-ZnAg, a broad-spectrum antiviral and antibacterial agent to treat infection disease and to provide immune support for symptom resolution. In addition, the company markets and distributes dietary supplements comprising rMetx, an aqueous zinc-silver ion dietary supplement; and KHC46, an aqueous gold dietary supplement of very low-concentration Au nanoparticles. Clene Inc. is headquartered in Salt Lake City, Utah.
6550 South Millrock Drive, Salt Lake City, UT, United States, 84121
801 676 9695
76
| Name | Title | Year Born |
|---|---|---|
| Mr. Robert Etherington MBA | CEO, Pres & Director | 1967 |
| Mr. Mark G. Mortenson | Co-Founder & Chief Science Officer | 1958 |
| Dr. Robert Glanzman M.D. | Chief Medical Officer | 1957 |
| Mr. Morgan R. Brown CPA, CPA, M.B.A., MBA | Chief Financial Officer | 1968 |
| Mr. Jerry Miraglia J.D. | Gen. Counsel & Corp. Sec. | NA |
| Mr. Michael T. Hotchkin | Chief Devel. Officer | NA |
| Ms. Mary Anne Mcneil | Head of HR | NA |
| Dr. Tae Heum Jeong D. Mgt. | Consultant | 1971 |
| Mr. Robert Etherington MBA | CEO, President & Director | 1967 |
| Mr. Morgan R. Brown CPA, M.B.A. | Chief Financial Officer | 1968 |
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