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Guardant Health, Inc., a precision oncology company, provides blood and tissue tests, and data sets in the United States and internationally. The company offers Guardant360 CDx test, a liquid biopsy test for tumor mutation profiling; Guardant360 Liquid test, which measures 740+ genes and supports all guideline-recommended biomarkers; Guardant Reveal test, a blood test that utilizes circulating tumor DNA to detect cancer at the molecular level; and Guardant360 Tissue test, a molecular profiling test for tumor tissue that provides genomic, transcriptomic, and epigenomic insights. It also provides Shield blood test for colorectal cancer screening in adults. In addition, the company offers GuardantINFINITY test that provides insights into the complexities of tumor molecular profiles and immune response to advance cancer research and therapy development; GuardantOMNI test covers 500 genes, including genes associated with homologous recombination repair deficiency and biomarkers for immuno-oncology applications; GuardantINFORM, which provides longitudinal biological insight into tumor evolution alongside longitudinal clinical outcomes; and GuardantConnect, an integrated software-based solution designed for clinical and biopharmaceutical customers to connect patients tested with assays with actionable alterations with potentially relevant clinical studies. Further, it provides Smart Platform, which delivers multiomic insights leveraging genomic, epigenomic, and RNA-based data that are scalable from research to the clinic. Additionally, the company offers development services, including companion diagnostic development and regulatory approval, clinical study setup, monitoring and maintenance, testing development and support, technologies licensing, and kit fulfillment and delivery of Shield screening tests. Guardant Health, Inc. was incorporated in 2011 and is headquartered in Palo Alto, California.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
Guardant Health offers blood-based genomic tests that analyze circulating tumor DNA to inform cancer treatment, monitoring and clinical trials; Guardant360 and related assays are used as companion diagnostics. Long-term growth could be supported by broader adoption of liquid biopsy, expansion into early-stage detection and surveillance, and pharma partnerships, which may make it attractive to investors seeking exposure to a scalable diagnostics platform.
Principal risks are reimbursement and regulatory uncertainty, strong competition from established diagnostics firms, and ongoing operating losses that create funding and execution risk.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -417.54M | -435.09M | -478.76M | -653.45M | -384.47M |
| Minority interest | - | - | 0.00M | 0.00M | -20.90M |
| Net income | -416.28M | -436.37M | -479.45M | -654.59M | -384.77M |
| Selling general administrative | 211.41M | 180.12M | 155.80M | 163.96M | 206.64M |
| Selling and marketing expenses | 494.66M | 364.94M | 295.23M | 299.83M | 191.88M |
| Gross profit | 633.01M | 449.22M | 336.90M | 293.21M | 250.74M |
| Reconciled depreciation | 39.74M | 42.39M | 42.88M | 35.96M | 22.27M |
| Ebit | -413.64M | -432.51M | -476.19M | -544.38M | -411.00M |
| Ebitda | -373.91M | -390.12M | -433.31M | -650.87M | -381.89M |
| Depreciation and amortization | 39.74M | 42.39M | 42.88M | -106.49M | 29.11M |
| Non operating income net other | - | - | - | -106.49M | 29.11M |
| Operating income | -436.30M | -443.59M | -564.73M | -544.38M | -411.00M |
| Other operating expenses | 1419.27M | 1182.61M | 1128.67M | 993.92M | 784.65M |
| Interest expense | 3.90M | 2.58M | 2.58M | 2.58M | 2.58M |
| Tax provision | -1.26M | 1.28M | 0.69M | 1.14M | 0.30M |
| Interest income | 34.09M | 53.69M | 35.37M | 6.07M | 3.93M |
| Net interest income | 30.20M | 51.11M | 32.79M | 3.49M | 1.35M |
| Income tax expense | -1.26M | 1.28M | 0.69M | 1.14M | 0.30M |
| Total revenue | 982.02M | 739.02M | 563.95M | 449.54M | 373.65M |
| Total operating expenses | 1070.26M | 892.81M | 901.62M | 837.59M | 661.74M |
| Cost of revenue | 349.01M | 289.80M | 227.05M | 156.32M | 122.91M |
| Total other income expense net | 18.76M | 8.51M | 85.96M | -109.07M | 26.53M |
| Net income from continuing ops | -416.28M | -436.37M | -479.45M | -654.59M | -384.77M |
| Net income applicable to common shares | - | - | - | -654.59M | -405.67M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 2013.66M | 1485.61M | 1786.42M | 1609.98M | 2204.50M |
| Intangible assets | 25.92M | 6.76M | 8.98M | 11.73M | 14.21M |
| Other current assets | 40.72M | 33.80M | 27.74M | 31.51M | 53.05M |
| Total liab | 2112.97M | 1625.26M | 1627.74M | 1549.81M | 1559.49M |
| Total stockholder equity | -99.31M | -139.65M | 158.68M | 60.18M | 645.00M |
| Other current liab | 197.53M | 122.35M | 108.26M | -21.88M | 152.93M |
| Common stock | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Capital stock | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Retained earnings | -2994.51M | -2578.24M | -2141.86M | -1662.41M | -1007.83M |
| Other liab | - | - | - | 9.18M | 3.93M |
| Good will | 77.26M | 3.29M | 3.29M | 3.29M | 3.29M |
| Other assets | - | - | - | 36.45M | 60.94M |
| Cash | 378.20M | 525.54M | 1133.54M | 141.65M | 492.20M |
| Total current liabilities | 302.73M | 225.58M | 205.92M | 193.22M | 194.69M |
| Current deferred revenue | 50.75M | 35.47M | 17.96M | 17.40M | 11.33M |
| Net debt | 1304.26M | 810.51M | 220.23M | 1227.64M | 868.67M |
| Short term debt | - | 29.21M | 27.95M | 21.88M | 12.86M |
| Short long term debt total | 1682.46M | 1336.05M | 1353.76M | 1369.28M | 1360.87M |
| Other stockholder equity | 2900.06M | 2443.79M | 2304.22M | 1742.11M | 1657.59M |
| Property plant equipment | - | - | - | 167.92M | 313.90M |
| Total current assets | 1466.05M | 1055.11M | 1347.11M | 1191.59M | 1114.13M |
| Long term investments | - | - | - | 0.00M | 698.03M |
| Net tangible assets | - | - | - | 45.16M | 627.51M |
| Short term investments | 823.39M | 314.44M | 35.10M | 869.58M | 440.55M |
| Net receivables | 137.85M | 110.25M | 88.78M | 97.26M | 97.65M |
| Long term debt | 1504.00M | 1142.55M | 1139.97M | 1137.39M | 1134.82M |
| Inventory | 85.88M | 71.08M | 61.95M | 51.60M | 30.67M |
| Accounts payable | 54.44M | 38.55M | 51.74M | 175.82M | 17.58M |
| Accumulated other comprehensive income | -4.85M | -5.20M | -3.67M | -19.52M | -4.76M |
| Common stock total equity | - | - | - | 0.00M | 0.00M |
| Retained earnings total equity | - | - | - | -1662.41M | -1007.83M |
| Non currrent assets other | 139.67M | 141.37M | 124.18M | 61.45M | 60.94M |
| Non current assets total | 547.61M | 430.50M | 439.31M | 418.39M | 1090.37M |
| Capital lease obligations | 206.14M | 193.50M | 213.80M | 231.89M | 226.05M |
| Long term debt total | - | - | - | 1137.39M | 1134.82M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | -519.91M | -261.31M | 247.42M | 149.82M | 51.30M |
| Change to liabilities | - | - | - | 9.87M | 37.57M |
| Total cashflows from investing activities | -627.20M | -261.31M | 840.25M | 149.82M | -63.16M |
| Net borrowings | 402.50M | 0.00M | 0.00M | -0.07M | -0.78M |
| Total cash from financing activities | 671.13M | -1.00M | 477.38M | -189.09M | -66.82M |
| Change to operating activities | - | - | - | 11.91M | 0.43M |
| Net income | -416.28M | -436.37M | -479.45M | -654.59M | -384.77M |
| Change in cash | -140.34M | -503.93M | 991.74M | -842.63M | -340.69M |
| Begin period cash flow | 629.75M | 1133.69M | 141.95M | 492.29M | 832.98M |
| End period cash flow | 489.42M | 629.75M | 1133.69M | -350.34M | 492.29M |
| Total cash from operating activities | -184.76M | -239.86M | -324.98M | -309.46M | -209.02M |
| Issuance of capital stock | 345.00M | 0.00M | 493.12M | - | 0.00M |
| Depreciation | 39.74M | 42.39M | 42.88M | 35.96M | 22.27M |
| Other cashflows from investing activities | - | - | 1.53M | -23.97M | -39.42M |
| Change to inventory | -14.79M | -9.13M | -10.35M | -20.93M | -7.96M |
| Change to account receivables | -28.18M | -21.39M | 8.38M | 0.38M | -44.35M |
| Sale purchase of stock | 13.59M | 11.72M | 10.15M | 9.32M | 9.75M |
| Other cashflows from financing activities | 569.68M | -15.83M | -15.74M | -200.96M | -76.43M |
| Change to netincome | - | - | - | 104.27M | 153.88M |
| Capital expenditures | 48.31M | 35.09M | 20.49M | 77.46M | 75.03M |
| Change receivables | - | - | - | 0.38M | -44.35M |
| Cash flows other operating | - | - | - | 208.41M | -1.07M |
| Cash and cash equivalents changes | - | - | - | -348.74M | -339.00M |
| Change in working capital | 9.78M | -60.86M | 53.84M | 61.56M | -40.47M |
| Stock based compensation | 166.22M | 140.41M | 90.76M | 94.69M | 151.45M |
| Other non cash items | 15.78M | 74.58M | -33.01M | 152.91M | 29.61M |
| Free cash flow | -233.07M | -274.94M | -345.46M | -386.92M | -284.05M |
Sector: Healthcare Industry: Diagnostics & Research
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| GH Guardant Health Inc |
1.06 0.69% |
155.84 | - | - | 12.07 | 55.67 | 12.68 | -5.40 |
| TMO Thermo Fisher Scientific Inc |
-15.12 2.11% |
702.59 | 34.71 | 23.87 | 4.62 | 4.43 | 5.29 | 20.89 |
| DHR Danaher Corporation |
-1.34 0.57% |
233.97 | 29.09 | 28.01 | 5.67 | 3.20 | 6.00 | 19.09 |
| WUXIF WuXi AppTec Co. Ltd |
- -% |
24.91 | 22.29 | 17.95 | 1.53 | 5.98 | 8.39 | 14.30 |
| WUXAY WuXi AppTec Co. Ltd |
-0.17 0.68% |
24.93 | 23.28 | 18.73 | 1.51 | 6.24 | 8.39 | 14.30 |
Guardant Health, Inc., a precision oncology company, provides blood and tissue tests, and data sets in the United States and internationally. The company offers Guardant360 CDx test, a liquid biopsy test for tumor mutation profiling; Guardant360 Liquid test, which measures 740+ genes and supports all guideline-recommended biomarkers; Guardant Reveal test, a blood test that utilizes circulating tumor DNA to detect cancer at the molecular level; and Guardant360 Tissue test, a molecular profiling test for tumor tissue that provides genomic, transcriptomic, and epigenomic insights. It also provides Shield blood test for colorectal cancer screening in adults. In addition, the company offers GuardantINFINITY test that provides insights into the complexities of tumor molecular profiles and immune response to advance cancer research and therapy development; GuardantOMNI test covers 500 genes, including genes associated with homologous recombination repair deficiency and biomarkers for immuno-oncology applications; GuardantINFORM, which provides longitudinal biological insight into tumor evolution alongside longitudinal clinical outcomes; and GuardantConnect, an integrated software-based solution designed for clinical and biopharmaceutical customers to connect patients tested with assays with actionable alterations with potentially relevant clinical studies. Further, it provides Smart Platform, which delivers multiomic insights leveraging genomic, epigenomic, and RNA-based data that are scalable from research to the clinic. Additionally, the company offers development services, including companion diagnostic development and regulatory approval, clinical study setup, monitoring and maintenance, testing development and support, technologies licensing, and kit fulfillment and delivery of Shield screening tests. Guardant Health, Inc. was incorporated in 2011 and is headquartered in Palo Alto, California.
3100 Hanover Street, Palo Alto, CA, United States, 94304
855 698 8887
2490
| Name | Title | Year Born |
|---|---|---|
| Dr. Helmy Eltoukhy Ph.D. | Co-Founder, Co-CEO & Chairman | 1979 |
| Dr. AmirAli Talasaz Ph.D. | Co-CEO & Director | 1980 |
| Mr. Michael Bell | Chief Financial Officer | 1969 |
| Mr. John G. Saia | Chief Legal Officer | 1973 |
| Dr. Craig Eagle M.D. | Chief Medical Officer | 1967 |
| Mr. Christopher Freeman | Chief Commercial Officer of Oncology Bus. | 1974 |
| Mr. Andy Ament | Sr. VP of Operations | NA |
| Darya Chudova | Sr. VP of Technology | NA |
| Mr. Kumud Kalia | Chief Information Officer | NA |
| Ms. Jennifer Higgins | VP of Public Affairs | NA |
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