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InflaRx N.V., a clinical-stage biopharmaceutical company, discovers and develops inhibitors using C5a technology in Germany and the United States. The company's C5a is an inflammatory mediator to treat variety of autoimmune and other inflammatory diseases. Its lead product candidate is vilobelimab, a a first-in-class monoclonal anti-human complement factor C5a antibody, which is in Phase 3 clinical trial for the treatment for patients suffering from early septic organ dysfunction, biological proof of concept was established, demonstrating its unique C5a blocking ability and selectivity; Izicopan, an oral, low molecular weight drug to target C5aR with high affinity and selectivity has completed completing Phase 2a trials; and IFX002, an advancement of vilobelimab technology, which is in preclinical development for the treatment of chronic inflammatory indications. It has co-development agreement with Staidson (Beijing) BioPharmaceuticals Co., Ltd.; Cell line sales agreement with Catalent Pharma Solutions LLC; Clinical Trial Collaboration Agreement with the U.S. DHHSs, Administration for Strategic Preparedness and Response (ASPR), BARDA and PPD Development, L.P., or PPD. InflaRx N.V. was formerly known as Fireman B.V. and changed its name to InflaRx N.V. in 2017. The company was founded in 2007 and is headquartered in Jena, Germany.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
InflaRx N.V. is a clinical-stage biopharmaceutical company developing monoclonal antibody therapies that inhibit complement component C5a for severe inflammatory diseases. Its long-term growth may be supported by positive late-stage clinical outcomes, regulatory approvals across indications, and potential licensing or commercialization partnerships that could benefit investors seeking exposure to targeted anti-inflammatory therapeutics.
Key investment risks include high clinical and regulatory execution risk, lack of commercial revenue requiring additional financing, concentrated single-asset exposure and significant competition from larger immunology companies.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -45.62M | -46.06M | -42.67M | -29.48M | -45.63M |
| Net income | -45.63M | -46.06M | -42.67M | -27.04M | -45.65M |
| Selling general administrative | 15.52M | 15.29M | 14.22M | 14.87M | 11.98M |
| Selling and marketing expenses | 2.05M | 4.04M | 1.91M | - | - |
| Gross profit | -7.24M | -3.15M | -0.47M | - | - |
| Reconciled depreciation | 0.42M | 0.49M | 0.58M | 0.60M | 0.67M |
| Ebit | -45.58M | -46.04M | -42.63M | -32.24M | -47.63M |
| Ebitda | -45.16M | -45.55M | -42.06M | -31.29M | -46.90M |
| Depreciation and amortization | 0.42M | 0.49M | 0.57M | 0.95M | 0.73M |
| Operating income | -48.26M | -52.91M | -44.59M | -32.24M | -47.63M |
| Other operating expenses | 48.29M | 53.07M | 44.66M | 32.24M | 47.63M |
| Interest expense | 0.04M | 0.02M | 0.04M | 0.05M | 0.02M |
| Tax provision | 0.01M | 0.01M | 0.00M | 0.00M | 0.00M |
| Interest income | 1.85M | 3.20M | 3.03M | 0.61M | 0.11M |
| Net interest income | 7.49M | 3.28M | 3.35M | 0.31M | 0.04M |
| Income tax expense | 0.01M | 0.01M | -0.00M | -2.44M | 0.02M |
| Total revenue | 0.03M | 0.17M | 0.06M | 0.00M | 0.00M |
| Total operating expenses | 41.02M | 49.75M | 44.13M | 32.24M | 47.63M |
| Cost of revenue | 7.27M | 3.32M | 0.53M | - | - |
| Total other income expense net | 2.64M | 6.85M | 1.93M | 2.75M | 2.00M |
| Net income from continuing ops | -45.63M | -46.06M | -34.76M | -29.48M | -45.63M |
| Net income applicable to common shares | - | - | - | - | -45.63M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 55.19M | 76.02M | 120.31M | 102.40M | 125.14M |
| Intangible assets | 0.04M | 0.01M | 0.07M | 0.14M | 0.24M |
| Other current assets | 5.75M | 46.38M | 3.95M | 14.17M | 10.98M |
| Total liab | 13.65M | 14.60M | 17.64M | 14.05M | 19.86M |
| Total stockholder equity | 41.54M | 61.42M | 102.67M | 88.35M | 105.28M |
| Other current liab | 7.32M | 10.35M | 11.38M | 1.46M | 8.44M |
| Common stock | 8.67M | 7.12M | 7.07M | 5.36M | 5.30M |
| Capital stock | 8.68M | 7.12M | 7.07M | 5.36M | 5.30M |
| Retained earnings | -377.67M | -332.19M | -286.36M | -243.46M | -213.98M |
| Other liab | - | - | - | - | 0.04M |
| Other assets | - | - | 0.00M | - | 0.34M |
| Cash | 16.02M | 18.38M | 12.78M | 16.27M | 26.25M |
| Total current liabilities | 12.98M | 14.17M | 16.86M | 13.03M | 18.76M |
| Current deferred revenue | - | - | 0.00M | 6.21M | 1.38M |
| Net debt | -15.12M | -17.57M | -11.66M | -14.91M | -24.82M |
| Short term debt | 0.26M | 0.41M | 0.37M | 0.37M | 0.37M |
| Short long term debt total | 0.90M | 0.81M | 1.12M | 1.36M | 1.43M |
| Other stockholder equity | 361.99M | 334.93M | 334.49M | 289.81M | 283.36M |
| Property plant equipment | - | - | - | - | 1.68M |
| Total current assets | 53.61M | 71.66M | 109.56M | 97.41M | 95.68M |
| Long term investments | 0.24M | 3.09M | 9.05M | 2.90M | 27.21M |
| Net tangible assets | - | - | - | - | 105.05M |
| Short term investments | 30.42M | 34.46M | 77.57M | 65.54M | 57.16M |
| Net receivables | 1.43M | 1.74M | 3.89M | 1.43M | 1.28M |
| Inventory | 0.00M | 6.90M | 11.38M | - | - |
| Accounts payable | 5.40M | 3.41M | 5.11M | 4.99M | 8.57M |
| Accumulated other comprehensive income | 48.54M | 51.56M | 47.47M | 36.64M | 30.59M |
| Non currrent assets other | 0.15M | 0.25M | 0.26M | 0.31M | 0.34M |
| Non current assets total | 1.58M | 4.36M | 10.75M | 4.99M | 29.46M |
| Capital lease obligations | 0.90M | 0.81M | 1.12M | 1.36M | 1.43M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | 3.35M | 52.36M | -18.72M | 19.36M | -25.91M |
| Change to liabilities | - | - | - | - | 8.62M |
| Total cashflows from investing activities | 3.11M | 52.36M | -17.70M | - | -25.95M |
| Net borrowings | -0.36M | -0.39M | -0.37M | - | -0.36M |
| Total cash from financing activities | 32.00M | 0.39M | 52.99M | 1.94M | 61.58M |
| Change to operating activities | - | - | - | - | -7.08M |
| Net income | -43.83M | -46.06M | -42.67M | -29.48M | -45.63M |
| Change in cash | -0.18M | 5.61M | -3.50M | -9.98M | 0.28M |
| Begin period cash flow | 16.20M | 12.77M | 16.27M | 26.25M | 25.97M |
| End period cash flow | 16.02M | 18.38M | 12.77M | 16.27M | 26.25M |
| Total cash from operating activities | -33.92M | -48.56M | -37.81M | -33.74M | -39.94M |
| Issuance of capital stock | 22.90M | 1.10M | 58.83M | 2.35M | 65.14M |
| Depreciation | 0.40M | 0.49M | 0.57M | 0.60M | 0.67M |
| Other cashflows from investing activities | -0.00M | 0.00M | -0.36M | - | - |
| Change to inventory | 6.63M | 4.47M | -11.37M | - | - |
| Change to account receivables | 2.12M | - | - | - | - |
| Other cashflows from financing activities | 0.01M | -0.32M | -3.12M | -0.05M | -3.20M |
| Change to netincome | - | - | - | - | 3.49M |
| Capital expenditures | 0.11M | 0.05M | 0.08M | 0.16M | 0.04M |
| Change in working capital | 4.66M | -2.28M | 1.00M | -9.77M | 1.54M |
| Stock based compensation | 4.44M | 4.07M | 3.41M | 6.04M | 4.33M |
| Other non cash items | 4.84M | -4.76M | -0.13M | -1.13M | -2.00M |
| Free cash flow | -34.03M | -48.60M | -37.89M | -33.91M | -39.97M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| IFRX InflaRx N.V. |
-0.04 3.32% |
1.31 | - | - | 9842.62 | 1.76 | 6145.05 | 0.50 |
| NVO Novo Nordisk A/S |
0.01 0.02% |
40.31 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
4.59 0.85% |
547.09 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
1.45 0.16% |
904.35 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
InflaRx N.V., a clinical-stage biopharmaceutical company, discovers and develops inhibitors using C5a technology in Germany and the United States. The company's C5a is an inflammatory mediator to treat variety of autoimmune and other inflammatory diseases. Its lead product candidate is vilobelimab, a a first-in-class monoclonal anti-human complement factor C5a antibody, which is in Phase 3 clinical trial for the treatment for patients suffering from early septic organ dysfunction, biological proof of concept was established, demonstrating its unique C5a blocking ability and selectivity; Izicopan, an oral, low molecular weight drug to target C5aR with high affinity and selectivity has completed completing Phase 2a trials; and IFX002, an advancement of vilobelimab technology, which is in preclinical development for the treatment of chronic inflammatory indications. It has co-development agreement with Staidson (Beijing) BioPharmaceuticals Co., Ltd.; Cell line sales agreement with Catalent Pharma Solutions LLC; Clinical Trial Collaboration Agreement with the U.S. DHHSs, Administration for Strategic Preparedness and Response (ASPR), BARDA and PPD Development, L.P., or PPD. InflaRx N.V. was formerly known as Fireman B.V. and changed its name to InflaRx N.V. in 2017. The company was founded in 2007 and is headquartered in Jena, Germany.
| Name | Title | Year Born |
|---|---|---|
| Dr. Niels C. Riedemann M.D., Ph.D. | Co-Founder, CEO & Exec. Director | 1972 |
| Prof. Renfeng Guo M.D. | Co-Founder, Chief Scientific Officer & Exec. Director | 1970 |
| Dr. Thomas Taapken Ph.D. | Chief Financial Officer | 1965 |
| Ms. Nicole Bertsch | Sr. Director & Head of HR | NA |
| Dr. Maria Habel PH.D. | Head of Preclinical R&D | 1982 |
| Ms. Evelyn Roth-Geissler Ph.D. | VP & Head of Clinical Operations | NA |
| Dr. Bruce P. Burnett Ph.D. | VP & Head of Medical Affairs | NA |
| Mr. Christian Schmid | VP and Head of Legal Affairs & Corp. Counsel | NA |
| Mr. Kafi Boaten | Sr. Director and Head of Supply & Clinical Trial Supplies | NA |
| Mr. Peter Hurt Ph.D. | Sr. Director and Head of Drug Safety & Pharmacovigiliance | NA |
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