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SpringWorks Therapeutics, Inc., a commercial-stage biopharmaceutical company, engages in the development and commercialization of medicines for underserved patient populations suffering from rare diseases and cancer. Its lead product candidate is OGSIVEO (nirogacestat), an oral small molecule gamma secretase inhibitor that is in Phase III DeFi trial for the treatment of desmoid tumors; and Nirogacestat, is also in Phase 2 clinical development as a monotherapy for the treatment of ovarian granulosa cell tumors (GCT), a subtype of ovarian cancer. The company is also involved in the development of mirdametinib, an oral small molecule MEK inhibitor that is in Phase 2b clinical trials for the treatment of neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN); mirdametinib + lifirafenib, a combination therapy that is in Phase 1b clinical trial in patients with advanced or refractory solid tumors; and mirdametinib in monotherapy and combination approaches to treat other genetically defined solid tumors, including Phase 1/2 clinical trial for the treatment of pediatric and young adult patients with low-grade gliomas. In addition, it develops Brimarafenib (BGB-3245), an oral selective small molecule inhibitor of monomeric and dimeric forms of activating BRAF mutations. The company has collaborations with BeiGene, Ltd. and GlaxoSmithKline LLC; and license agreements with Pfizer Inc. for nirogacestat and mirdametinib. It also has a license agreement with Katholieke Universiteit Leuven and the Flanders Institute for Biotechnology for a portfolio of novel small molecule inhibitors of the TEA Domain; and Dana-Farber Cancer Institute for a portfolio of novel small molecule inhibitors of Epidermal Growth Factor Receptor. The company was founded in 2017 and is headquartered in Stamford, Connecticut.
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| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Income before tax | -277.42M | -173.91M | -45.57M | -58.31M | -17.81M |
| Net income | -274.16M | -173.21M | -44.24M | -54.76M | -17.81M |
| Selling general administrative | 134.55M | 71.79M | 29.46M | 16.69M | 8.59M |
| Gross profit | 6.15M | - | 35.00M | - | - |
| Reconciled depreciation | 0.77M | 0.49M | 0.35M | 0.19M | 0.02M |
| Ebit | -281.44M | -173.47M | -46.32M | -59.24M | -18.49M |
| Ebitda | -280.67M | -172.98M | -45.98M | -59.05M | -18.47M |
| Depreciation and amortization | 0.77M | 0.49M | 0.35M | 0.19M | 0.02M |
| Operating income | -280.67M | -173.47M | -46.32M | -59.24M | -18.49M |
| Other operating expenses | 280.67M | 173.47M | 81.32M | 59.24M | 18.49M |
| Interest expense | -0.77M | 0.44M | 0.00M | 0.00M | 0.00M |
| Interest income | 6.29M | 0.70M | 1.33M | 3.55M | 0.68M |
| Net interest income | 6.29M | 0.70M | 1.33M | 3.55M | 0.68M |
| Income tax expense | -3.26M | -0.70M | -1.33M | -3.55M | 0.68M |
| Total revenue | 6.15M | 0.00M | 35.00M | 0.00M | 0.00M |
| Total operating expenses | 280.67M | 173.47M | 81.32M | 59.24M | 18.49M |
| Total other income expense net | 3.26M | -0.44M | 0.75M | 0.93M | 0.68M |
| Net income from continuing ops | -277.42M | -173.91M | -45.57M | -58.31M | -17.81M |
| Net income applicable to common shares | -277.42M | -173.91M | -45.57M | -50.58M | -17.81M |
| Breakdown | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Total assets | 725.79M | 630.24M | 452.49M | 576.19M | 334.83M |
| Intangible assets | 11.20M | - | - | - | - |
| Other current assets | 12.68M | 7.55M | 9.41M | 4.91M | 3.71M |
| Total liab | 99.57M | 72.05M | 30.10M | 19.13M | 12.76M |
| Total stockholder equity | 626.22M | -569.93M | 422.40M | 557.06M | 322.07M |
| Deferred long term liab | - | - | - | - | 0.70M |
| Other current liab | 65.57M | 39.24M | 25.38M | 14.88M | 9.32M |
| Common stock | 0.01M | 0.01M | 0.01M | 0.01M | 0.00M |
| Capital stock | 0.01M | 0.01M | 0.01M | 0.01M | 0.00M |
| Retained earnings | -895.03M | -569.93M | -292.51M | -118.60M | -73.03M |
| Other liab | - | 16.23M | - | 0.16M | 0.79M |
| Other assets | - | 3.23M | 3.27M | 2.57M | 1.70M |
| Cash | 176.05M | 67.49M | 103.96M | 147.09M | 327.65M |
| Total current liabilities | 78.17M | 51.05M | 29.97M | 17.61M | 11.97M |
| Current deferred revenue | 4.14M | 3.31M | - | - | - |
| Net debt | -169.00M | -62.24M | -102.67M | -144.35M | -327.65M |
| Short term debt | 1.06M | 0.48M | 1.16M | 1.38M | - |
| Short long term debt total | 7.06M | 5.25M | 1.29M | 2.73M | - |
| Other stockholder equity | 1520.06M | 0.76M | 715.22M | 675.62M | 395.10M |
| Property plant equipment | - | 18.27M | 4.20M | 3.02M | 0.80M |
| Total current assets | 500.91M | 599.76M | 382.91M | 513.40M | 331.36M |
| Long term investments | 185.34M | 8.99M | 62.11M | 57.21M | 0.98M |
| Net tangible assets | - | 558.19M | 422.40M | 557.06M | 322.07M |
| Short term investments | 303.15M | 524.72M | 269.54M | 361.39M | - |
| Net receivables | 5.93M | - | - | - | - |
| Inventory | 3.10M | - | - | - | - |
| Accounts payable | 7.40M | 8.01M | 3.43M | 1.35M | 2.65M |
| Accumulated other comprehensive income | 1.19M | -0.77M | -0.31M | 0.04M | -334.83M |
| Common stock total equity | - | - | - | 0.01M | 0.00M |
| Non currrent assets other | 4.25M | 3.23M | 3.27M | 2.57M | 1.70M |
| Non current assets total | 224.88M | 30.48M | 69.58M | 62.79M | 3.47M |
| Capital lease obligations | 7.06M | 5.25M | 1.29M | 2.73M | - |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Investments | -215.60M | 85.61M | -418.83M | -4.26M | -0.29M |
| Change to liabilities | 23.71M | 2.07M | -1.30M | 1.88M | 0.49M |
| Total cashflows from investing activities | -215.60M | 83.59M | -418.83M | -4.26M | -0.29M |
| Total cash from financing activities | 340.70M | 1.16M | 270.49M | 333.71M | 50.38M |
| Change to operating activities | 14.39M | 3.04M | 2.65M | 3.07M | 2.07M |
| Net income | -277.42M | -173.91M | -45.57M | -58.31M | -17.81M |
| Change in cash | -36.46M | -43.13M | -180.54M | 282.00M | 35.38M |
| Begin period cash flow | 104.53M | 147.65M | 328.19M | 46.19M | 10.27M |
| End period cash flow | 68.07M | 104.53M | 147.65M | 328.19M | 45.65M |
| Total cash from operating activities | -161.56M | -127.88M | -32.19M | -47.44M | -14.71M |
| Issuance of capital stock | 340.07M | 0.00M | 269.59M | 333.69M | 50.38M |
| Depreciation | 0.77M | 0.49M | 0.35M | 0.19M | 0.02M |
| Other cashflows from investing activities | - | - | - | -3.59M | - |
| Sale purchase of stock | -1.34M | - | - | 333.71M | 50.38M |
| Other cashflows from financing activities | 1.98M | 1.16M | 0.89M | 163.98M | 50.38M |
| Change to netincome | 76.99M | 40.42M | 11.69M | 5.72M | 1.07M |
| Capital expenditures | 10.20M | 2.02M | 0.64M | 0.67M | 0.29M |
| Change in working capital | 38.10M | 5.12M | 1.35M | 4.95M | 2.02M |
| Stock based compensation | 72.97M | 38.44M | 10.03M | 3.11M | 1.07M |
| Other non cash items | 4.02M | 0.99M | 1.05M | 2.61M | - |
| Free cash flow | -171.76M | -129.89M | -32.83M | -48.11M | -15.00M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| NVO Novo Nordisk A/S |
-0.54 1.32% |
40.55 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-2.37 0.43% |
544.66 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
-2.77 0.29% |
956.64 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
SpringWorks Therapeutics, Inc., a commercial-stage biopharmaceutical company, engages in the development and commercialization of medicines for underserved patient populations suffering from rare diseases and cancer. Its lead product candidate is OGSIVEO (nirogacestat), an oral small molecule gamma secretase inhibitor that is in Phase III DeFi trial for the treatment of desmoid tumors; and Nirogacestat, is also in Phase 2 clinical development as a monotherapy for the treatment of ovarian granulosa cell tumors (GCT), a subtype of ovarian cancer. The company is also involved in the development of mirdametinib, an oral small molecule MEK inhibitor that is in Phase 2b clinical trials for the treatment of neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN); mirdametinib + lifirafenib, a combination therapy that is in Phase 1b clinical trial in patients with advanced or refractory solid tumors; and mirdametinib in monotherapy and combination approaches to treat other genetically defined solid tumors, including Phase 1/2 clinical trial for the treatment of pediatric and young adult patients with low-grade gliomas. In addition, it develops Brimarafenib (BGB-3245), an oral selective small molecule inhibitor of monomeric and dimeric forms of activating BRAF mutations. The company has collaborations with BeiGene, Ltd. and GlaxoSmithKline LLC; and license agreements with Pfizer Inc. for nirogacestat and mirdametinib. It also has a license agreement with Katholieke Universiteit Leuven and the Flanders Institute for Biotechnology for a portfolio of novel small molecule inhibitors of the TEA Domain; and Dana-Farber Cancer Institute for a portfolio of novel small molecule inhibitors of Epidermal Growth Factor Receptor. The company was founded in 2017 and is headquartered in Stamford, Connecticut.
100 Washington Boulevard, Stamford, CT, United States, 06902
203 883 9490
305
| Name | Title | Year Born |
|---|---|---|
| Mr. Saqib Islam J.D. | CEO & Director | 1970 |
| Mr. Francis I. Perier Jr., M.B.A. | Chief Financial Officer | 1960 |
| Dr. Badreddin Edris Ph.D. | Chief Operating Officer | 1987 |
| Mr. Bhavesh Ashar | Chief Commercial Officer | 1966 |
| Mr. Michael P. Nofi | Chief Accounting Officer | 1971 |
| Ms. Kim Diamond | VP of Communications & Investor Relations | NA |
| Mr. Herschel S. Weinstein J.D. | Gen. Counsel & Sec. | 1956 |
| Mr. Daniel J. Pichl | Chief People Officer | 1983 |
| Dr. L. Mary Smith PH.D. | Chief Devel. Officer | 1967 |
| Dr. James Cassidy M.D., Ph.D. | Chief Medical Officer | NA |
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