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Tango Therapeutics, Inc., a biotechnology company, discovers and develops drugs for the treatment of cancer. Its lead program is TNG908, a synthetic lethal small molecule inhibitor of protein arginine methyltransferase 5 that is being developed as a treatment for cancers with methylthioadenosine phosphorylase deletions. The company develops TNG462, an oral small molecule methylthioadenosine-cooperative inhibitor for the treatment for cancers with methylthioadenosine phosphorylase deletions; TNG260, a co-repressor of repressor element-1 silencing transcription -selective inhibitor; TNG348, an ubiquitin-specific protease 1 inhibitor to treat patients with BRCA1 or BRCA2-mutant cancers; and Target 3 for STK11-mutant cancers. It has a strategic collaboration with Gilead Sciences, Inc. for the discovery, development, and commercialization of a pipeline of therapies for patients with cancer. Tango Therapeutics, Inc. was founded in 2017 and is headquartered in Boston, Massachusetts.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
Tango Therapeutics is a clinical-stage biotechnology company using functional genomics and synthetic lethality to discover and develop targeted cancer therapies, with a pipeline spanning discovery and clinical programs. Long-term growth may be driven by clinical progress, biomarker-directed patient selection, and leveraging its discovery platform to expand programs or secure collaborations. The precision-oncology focus and a platform-based approach may attract investors seeking exposure to novel cancer mechanisms.
Key risks include high clinical and regulatory uncertainty, substantial financing needs before potential commercialization, and intense competition in oncology that could limit market opportunities.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Income before tax | -108.12M | -57.94M | -51.97M | - |
| Net income | -108.18M | -58.23M | -51.86M | - |
| Selling general administrative | 30.02M | 17.60M | 9.87M | - |
| Gross profit | 24.86M | 37.04M | 7.66M | - |
| Reconciled depreciation | 1.61M | 0.90M | 0.72M | - |
| Ebit | -112.68M | -59.09M | -52.20M | -15.16M |
| Ebitda | -111.07M | -58.19M | -51.48M | - |
| Depreciation and amortization | 1.61M | 0.90M | 0.72M | - |
| Non operating income net other | -1.45M | -1.03M | - | - |
| Operating income | -111.07M | -58.19M | -52.20M | - |
| Other operating expenses | 135.93M | 95.23M | 59.86M | - |
| Interest expense | 2.95M | 1.14M | 0.00M | 0.00M |
| Tax provision | 0.05M | 0.29M | 0.00M | - |
| Interest income | 1.46M | 0.49M | 0.11M | - |
| Net interest income | 1.46M | 0.49M | 0.11M | - |
| Income tax expense | 0.05M | 0.29M | -0.11M | - |
| Total revenue | 24.86M | 37.04M | 7.66M | - |
| Total operating expenses | 135.93M | 95.23M | 59.86M | - |
| Total other income expense net | 2.95M | 0.25M | 0.23M | - |
| Net income from continuing ops | -108.18M | -58.23M | -51.97M | - |
| Net income applicable to common shares | -108.18M | -58.23M | -51.97M | -14.10M |
| Breakdown | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Total assets | 402.57M | 436.47M | 500.15M | 207.25M | - |
| Other current assets | 8.80M | 6.57M | 4.52M | 1.31M | - |
| Total liab | 149.46M | 186.99M | 155.41M | 168.65M | - |
| Total stockholder equity | 253.11M | 249.48M | 344.75M | 38.60M | - |
| Other current liab | 15.40M | 17.53M | 9.94M | 6.14M | 19.93M |
| Common stock | 0.10M | 0.09M | 0.09M | 0.04M | 0.01M |
| Capital stock | 0.10M | 0.09M | 0.09M | 0.04M | - |
| Retained earnings | -371.26M | -269.51M | -161.34M | -103.10M | -51.13M |
| Other liab | - | - | 114.72M | 120.81M | 14.12M |
| Other assets | - | - | 1.73M | 166.82M | 2.28M |
| Cash | 66.39M | 59.97M | 142.75M | 28.38M | - |
| Total current liabilities | 45.94M | 55.55M | 40.69M | 40.92M | 25.85M |
| Current deferred revenue | 25.67M | 31.79M | 26.02M | 31.98M | - |
| Net debt | -27.46M | -18.84M | -141.24M | -20.50M | - |
| Short term debt | 2.08M | 1.77M | 1.50M | 0.96M | - |
| Short long term debt total | 38.92M | 41.13M | 1.50M | 7.88M | - |
| Other stockholder equity | 624.08M | 522.61M | 506.76M | 141.64M | 0.01M |
| Property plant equipment | - | 10.88M | 6.09M | 11.30M | 11.83M |
| Total current assets | 346.54M | 375.27M | 492.34M | 193.63M | 41.66M |
| Net tangible assets | - | 249.48M | 344.75M | -97.94M | -47.80M |
| Short term investments | 270.50M | 306.17M | 342.51M | 161.94M | - |
| Net receivables | 0.00M | 2.00M | 2.00M | 2.00M | - |
| Inventory | - | 0.57M | 0.57M | - | - |
| Accounts payable | 2.79M | 4.45M | 3.23M | 1.84M | 0.67M |
| Accumulated other comprehensive income | 0.19M | -3.71M | -0.77M | 0.02M | - |
| Common stock total equity | - | 0.09M | 0.09M | 157.36M | - |
| Retained earnings total equity | - | -269.51M | -161.34M | - | - |
| Non currrent assets other | 2.61M | 3.43M | 1.73M | 2.32M | - |
| Non current assets total | 56.03M | 61.20M | 7.82M | 13.62M | - |
| Capital lease obligations | 38.92M | 41.13M | 1.50M | 7.88M | - |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Investments | 34.09M | -181.60M | -144.32M | 2.67M |
| Change to liabilities | -8.13M | -10.81M | 120.25M | -15.22M |
| Total cashflows from investing activities | 26.40M | -183.43M | -145.47M | 0.85M |
| Total cash from financing activities | 1.61M | 357.32M | 80.88M | 11.00M |
| Change to operating activities | - | -0.54M | 0.42M | 1.70M |
| Net income | -108.18M | -58.23M | -51.97M | -14.10M |
| Change in cash | -81.07M | 114.36M | 5.49M | -12.96M |
| Begin period cash flow | 145.02M | 30.66M | 25.17M | - |
| End period cash flow | 63.96M | 145.02M | 30.66M | 25.17M |
| Total cash from operating activities | -109.08M | -59.53M | 70.07M | -24.80M |
| Issuance of capital stock | 0.00M | 29.99M | 80.84M | - |
| Depreciation | 1.61M | 0.90M | 0.72M | 0.64M |
| Other cashflows from investing activities | - | - | -0.04M | -0.04M |
| Change to inventory | - | - | 0.42M | - |
| Change to account receivables | - | 0.00M | -2.00M | -2.00M |
| Sale purchase of stock | - | 31.05M | - | - |
| Other cashflows from financing activities | -0.01M | 327.33M | -145.47M | 326.28M |
| Change to netincome | 13.56M | 9.16M | 2.65M | 2.18M |
| Capital expenditures | 7.69M | 1.84M | 1.11M | 1.82M |
| Cash flows other operating | -7.94M | -3.29M | - | - |
| Cash and cash equivalents changes | -81.07M | 114.36M | - | - |
| Change in working capital | -18.49M | -11.35M | 118.67M | - |
| Stock based compensation | 14.23M | 7.83M | 1.76M | - |
| Other non cash items | 1.75M | 1.32M | 0.89M | - |
| Free cash flow | -116.77M | -61.36M | 68.97M | - |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| TNGX Tango Therapeutics Inc |
1.01 4.70% |
22.51 | - | - | 21.50 | 3.10 | 13.35 | -4.36 |
| NVO Novo Nordisk A/S |
0.47 1.18% |
40.78 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
0.34 0.06% |
547.43 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
8.76 0.97% |
913.11 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Tango Therapeutics, Inc., a biotechnology company, discovers and develops drugs for the treatment of cancer. Its lead program is TNG908, a synthetic lethal small molecule inhibitor of protein arginine methyltransferase 5 that is being developed as a treatment for cancers with methylthioadenosine phosphorylase deletions. The company develops TNG462, an oral small molecule methylthioadenosine-cooperative inhibitor for the treatment for cancers with methylthioadenosine phosphorylase deletions; TNG260, a co-repressor of repressor element-1 silencing transcription -selective inhibitor; TNG348, an ubiquitin-specific protease 1 inhibitor to treat patients with BRCA1 or BRCA2-mutant cancers; and Target 3 for STK11-mutant cancers. It has a strategic collaboration with Gilead Sciences, Inc. for the discovery, development, and commercialization of a pipeline of therapies for patients with cancer. Tango Therapeutics, Inc. was founded in 2017 and is headquartered in Boston, Massachusetts.
| Name | Title | Year Born |
|---|---|---|
| Dr. Barbara L. Weber M.D. | Pres, CEO & Director | 1956 |
| Ms. Daniella Beckman CPA | Chief Financial Officer | 1979 |
| Dr. Alan Huang Ph.D. | Chief Scientific Officer | 1973 |
| Dr. Alan Ashworth FRS, Ph.D. | Founder & Member of Scientific Advisory Board | 1961 |
| Dr. Levi Garraway M.D., Ph.D. | Founder | NA |
| Dr. William G. Kaelin Jr., M.D. | Founder & Member of Scientific Advisory Board | 1958 |
| Dr. Timothy K. Lu M.D., Ph.D. | Founder | 1981 |
| Dr. Antoni Ribas M.D., Ph.D. | Founder & Member of Scientific Advisory Board | 1967 |
| Mr. Douglas J. Barry Esq., J.D. | Gen. Counsel, Chief Compliance Officer & Corp. Sec. | 1970 |
| Mr. John C. Ross M.S. | VP of HR | NA |
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