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Tempest Therapeutics, Inc., a clinical-stage biotechnology company, develops small molecule therapeutics to treat cancer. Its lead product candidates include Amezalpat, an oral small molecule selective antagonist of peroxisome proliferator-activated receptor alpha for the treatment of first-line unresectable or metastatic hepatocellular carcinoma that completed Phase 2 clinical trial; and TPST-1495, a small-molecule dual antagonist of the EP2 and EP4 receptors of prostaglandin E2 for treating various cancers. The company has a collaboration agreement with F. Hoffmann-La Roche Ltd. for the development of Amezalpat into a global first-line randomized study; and has a product development and investigator-initiated trial collaboration agreement with Heibei Senlang Biotechnology Co., Ltd. to develop TPST-4003 product candidate. Tempest Therapeutics, Inc. is headquartered in Brisbane, California.
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| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -26.26M | -41.84M | -29.49M | -35.71M | -28.30M |
| Net income | -26.26M | -41.84M | -29.49M | -36.78M | -29.55M |
| Selling general administrative | 13.97M | 13.55M | 11.66M | 12.11M | 9.82M |
| Selling and marketing expenses | - | - | 0.38M | - | - |
| Gross profit | - | -0.39M | -0.38M | -1.81M | -1.27M |
| Reconciled depreciation | 0.27M | 0.39M | 0.51M | 0.64M | 0.37M |
| Ebit | -26.05M | -40.53M | -29.16M | -34.64M | -26.99M |
| Ebitda | -25.79M | -40.14M | -28.78M | -34.09M | -26.65M |
| Depreciation and amortization | 0.27M | 0.39M | 0.38M | 0.55M | 0.34M |
| Operating income | -26.57M | -42.03M | -29.16M | -34.64M | -26.99M |
| Other operating expenses | 26.57M | 42.03M | 29.16M | 34.64M | 26.99M |
| Interest expense | 0.21M | 1.32M | 1.45M | 1.62M | 1.28M |
| Tax provision | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Interest income | 0.52M | 1.50M | 1.10M | 0.55M | 0.07M |
| Net interest income | 0.31M | 0.18M | -1.50M | -1.62M | -1.28M |
| Income tax expense | - | -41.84M | - | 1.07M | 1.25M |
| Total revenue | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 26.57M | 41.64M | 28.78M | 34.64M | 26.99M |
| Cost of revenue | - | 0.39M | 0.38M | 1.81M | 1.27M |
| Total other income expense net | 0.31M | 0.18M | -0.33M | -1.07M | -1.32M |
| Net income from continuing ops | -26.26M | -41.84M | -31.11M | -35.71M | -28.30M |
| Net income applicable to common shares | - | - | - | - | -28.30M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 16.93M | 41.49M | 51.60M | 46.09M | 73.24M |
| Other current assets | 0.56M | 1.21M | 1.13M | 1.27M | 0.55M |
| Total liab | 10.26M | 22.36M | 24.84M | 27.98M | 37.12M |
| Total stockholder equity | 6.67M | 19.13M | 26.77M | 18.11M | 36.12M |
| Other current liab | 1.08M | 4.55M | 3.33M | 4.76M | 17.59M |
| Common stock | 0.01M | 0.04M | 0.02M | 0.01M | 0.01M |
| Capital stock | 0.01M | 0.04M | 0.02M | 0.01M | 0.01M |
| Retained earnings | -233.37M | -207.11M | -165.26M | -135.77M | -100.06M |
| Other assets | - | - | - | - | 0.11M |
| Cash | 7.71M | 30.27M | 39.23M | 31.23M | 51.83M |
| Total current liabilities | 3.31M | 14.22M | 9.41M | 7.28M | 20.03M |
| Net debt | 0.43M | -14.90M | -18.57M | -9.12M | -33.29M |
| Short term debt | 1.19M | 7.22M | 5.24M | 1.41M | 1.44M |
| Short long term debt | - | 6.35M | 4.29M | - | - |
| Short long term debt total | 8.14M | 15.37M | 20.66M | 22.11M | 18.54M |
| Other stockholder equity | 240.03M | 226.19M | 192.01M | 153.87M | 136.17M |
| Property plant equipment | - | - | - | - | 4.16M |
| Total current assets | 8.27M | 31.47M | 40.36M | 32.95M | 68.96M |
| Net tangible assets | - | - | - | - | 36.12M |
| Net receivables | - | - | - | 0.45M | 15.00M |
| Long term debt | - | - | 6.26M | 10.37M | 15.07M |
| Inventory | - | - | - | - | 1.58M |
| Accounts payable | 1.04M | 2.45M | 0.84M | 1.11M | 0.99M |
| Accumulated other comprehensive income | - | - | 0.00M | - | -73.24M |
| Non currrent assets other | 0.52M | 0.10M | 0.06M | 0.43M | 0.11M |
| Non current assets total | 8.66M | 10.01M | 11.24M | 13.14M | 4.28M |
| Capital lease obligations | 8.14M | 9.01M | 10.11M | 11.74M | 3.47M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | - | -0.43M | -0.52M | -0.56M | -0.10M |
| Change to liabilities | - | - | - | - | -0.21M |
| Total cashflows from investing activities | - | -0.43M | - | - | -0.10M |
| Net borrowings | -6.43M | -4.40M | - | - | 15.00M |
| Total cash from financing activities | 4.26M | 24.50M | 35.60M | 11.40M | 59.06M |
| Change to operating activities | - | - | - | - | -0.40M |
| Net income | -26.26M | -41.84M | -29.49M | -35.71M | -28.30M |
| Change in cash | -22.56M | -8.96M | 8.00M | -20.23M | 33.01M |
| Begin period cash flow | 30.71M | 39.67M | 31.23M | 51.83M | 18.82M |
| End period cash flow | 8.15M | 30.71M | 39.23M | 31.60M | 51.83M |
| Total cash from operating activities | -26.82M | -33.03M | -27.36M | -31.07M | -25.96M |
| Issuance of capital stock | 7.33M | 28.59M | 1.27M | 16.14M | 33.42M |
| Depreciation | 0.27M | 0.39M | 0.38M | 0.64M | 0.37M |
| Other cashflows from investing activities | - | - | - | - | 0.04M |
| Other cashflows from financing activities | 4.26M | 0.31M | 0.04M | 7.28M | 40.54M |
| Change to netincome | - | - | - | - | 2.58M |
| Capital expenditures | 0.00M | 0.43M | 0.17M | 0.56M | 0.14M |
| Change in working capital | -5.13M | 1.61M | -2.68M | 0.87M | -0.61M |
| Stock based compensation | 3.12M | 5.30M | 2.55M | 1.56M | 1.10M |
| Other non cash items | 1.19M | 1.51M | 5.46M | 1.57M | 1.48M |
| Free cash flow | -26.82M | -33.46M | -27.53M | -31.63M | -26.09M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|
| TPST Tempest Therapeutics Inc |
0.02 6.09% |
0.40 | - | - | - | 22.94 | 0.31 |
| NVO Novo Nordisk A/S |
0.41 1.00% |
41.10 | 41.58 | 31.15 | 2.13 | 32.99 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-0.86 0.16% |
547.03 | 30.22 | 24.27 | 10.36 | 6.50 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
43.35 4.73% |
959.41 | 29.07 | 20.12 | 7.57 | 3.82 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 36.06 |
Tempest Therapeutics, Inc., a clinical-stage biotechnology company, develops small molecule therapeutics to treat cancer. Its lead product candidates include Amezalpat, an oral small molecule selective antagonist of peroxisome proliferator-activated receptor alpha for the treatment of first-line unresectable or metastatic hepatocellular carcinoma that completed Phase 2 clinical trial; and TPST-1495, a small-molecule dual antagonist of the EP2 and EP4 receptors of prostaglandin E2 for treating various cancers. The company has a collaboration agreement with F. Hoffmann-La Roche Ltd. for the development of Amezalpat into a global first-line randomized study; and has a product development and investigator-initiated trial collaboration agreement with Heibei Senlang Biotechnology Co., Ltd. to develop TPST-4003 product candidate. Tempest Therapeutics, Inc. is headquartered in Brisbane, California.
2000 Sierra Point Parkway, Brisbane, CA, United States, 94005
415 798 8589
4
| Name | Title | Year Born |
|---|---|---|
| Mr. Stephen R. Brady J.D., LLM | CEO & Director | 1970 |
| Dr. Thomas W. Dubensky Jr., Ph.D. | Pres & Director | 1958 |
| Dr. Samuel Whiting M.D., Ph.D. | Exec. VP & Chief Medical Officer | NA |
| Mr. Nicholas Maestas | VP of Strategy & Fin. and Sec. | 1980 |
| Mr. Justin Trojanowski | Corp. Controller, Treasurer & Principal Accounting Officer | 1988 |
| Mr. Petpiboon Prasit | Acting Chief Scientific Officer & Exec. Director | NA |
| Dr. Sharon Sakai Ph.D., RAC | Head of Regulatory & Quality | NA |
| Dr. Anne Moon | Sr. VP and Head of Project Team Leadership, Project Management & Portfolio Management | NA |
| Mr. Stephen R. Brady J.D., LLM | CEO, President & Director | 1970 |
| Dr. Samuel Whiting M.D., Ph.D. | Executive VP & Chief Medical Officer | 1966 |
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