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Zevra Therapeutics, Inc., a commercial-stage company, focuses on addressing unmet needs for the treatment of rare diseases in the United States. The company develops its products through Ligand Activated Technology platform. Its lead product candidate is KP1077, consisting of KP1077IH, which is under Phase 2 clinical trial for the treatment of idiopathic hypersomnia, and KP1077N, which is under Phase 1/2 clinical trial to treat narcolepsy. The company is also developing Celiprolol, a prodrug product candidate that is under Phase 3 clinical trial for the treatment of vascular Ehlers Danlos syndrome. In addition, it offers AZSTARYS, a once-daily treatment for attention deficit and hyperactivity disorder in patients aged six years and older; OLPRUVA to treat urea cycle disorders; and MIPLYFFA for the treatment of niemann pick disease type C, an ultra-rare neurodegenerative lysosomal storage disorder. The company has collaboration and license agreement with Commave Therapeutics SA to develop, manufacture and commercialize the company's product candidates containing SDX and d-methylphenidate; and license agreement with Acer and Relief Therapeutics, Inc. to develop and commercialize rights for OLPRUVA. The company was formerly known as KemPharm, Inc. and changed its name to Zevra Therapeutics, Inc. in February 2023. Zevra Therapeutics, Inc. was incorporated in 2006 and is headquartered in Celebration, Florida.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
Public disclosures on Zevra Therapeutics (NASDAQ: ZVRA) are sparse; available materials identify it as a biotechnology company developing therapeutic candidates. Its long-term growth may depend on clinical progress, regulatory approvals, partnerships and access to financing, and investors may find potential upside if development milestones are achieved.
Key risks include clinical and regulatory setbacks, high probability of financing-related dilution, and sparse public disclosure that increases uncertainty about pipeline depth and execution.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Income before tax | -42.33M | -8.52M | -12.79M | -24.54M | -56.59M |
| Net income | -41.54M | -8.55M | -12.76M | -24.52M | -56.47M |
| Selling general administrative | 15.34M | 8.70M | 7.92M | 10.82M | 12.51M |
| Gross profit | 10.12M | 26.59M | 11.98M | 9.89M | - |
| Reconciled depreciation | 0.94M | 0.26M | 0.27M | 0.30M | - |
| Ebit | -24.84M | 7.73M | -4.78M | -20.34M | -53.85M |
| Ebitda | -24.08M | 7.98M | -4.69M | -20.03M | -53.52M |
| Depreciation and amortization | 0.76M | 0.25M | 0.09M | 0.31M | 0.32M |
| Operating income | -24.84M | 7.73M | -4.78M | -20.34M | -55.90M |
| Other operating expenses | 35.30M | 20.92M | 18.07M | 33.18M | 54.27M |
| Interest expense | 0.34M | 0.38M | 7.09M | 6.51M | 7.09M |
| Tax provision | -0.79M | 0.03M | -0.03M | -0.02M | - |
| Interest income | 0.76M | 0.25M | 0.09M | 0.31M | - |
| Net interest income | 0.42M | -0.13M | -7.00M | -6.21M | - |
| Income tax expense | -0.79M | 0.03M | -0.03M | -0.02M | -0.13M |
| Total revenue | 10.46M | 28.65M | 13.29M | 12.84M | - |
| Total operating expenses | 34.96M | 18.86M | 16.76M | 30.23M | 54.27M |
| Cost of revenue | 0.34M | 2.06M | 1.30M | 2.94M | - |
| Total other income expense net | -17.49M | -16.25M | -8.01M | -4.21M | 4.34M |
| Net income from continuing ops | -41.54M | -8.55M | -12.76M | -24.52M | - |
| Net income applicable to common shares | -41.54M | -62.90M | -12.76M | -24.52M | - |
| Breakdown | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 |
| Total assets | 178.13M | 172.33M | 115.53M | 132.94M | 11.21M |
| Intangible assets | 68.99M | 69.23M | - | - | - |
| Other current assets | 4.05M | 26.51M | 1.88M | 1.18M | 1.48M |
| Total liab | 138.46M | 110.46M | 29.72M | 5.82M | 77.62M |
| Total stockholder equity | 39.67M | 61.86M | 85.81M | 127.12M | -66.41M |
| Other current liab | 6.14M | 21.49M | 2.98M | 0.84M | 0.17M |
| Common stock | 0.01M | 0.00M | 0.00M | 0.00M | - |
| Capital stock | 0.01M | - | 0.00M | 0.00M | 0.00M |
| Retained earnings | -505.29M | -399.78M | -308.57M | -267.03M | -258.47M |
| Other liab | - | - | 4.35M | 0.35M | 0.43M |
| Good will | 4.70M | 4.70M | - | - | - |
| Other assets | - | - | 0.72M | 0.44M | 0.44M |
| Cash | 33.78M | 43.05M | 65.47M | 112.35M | 4.21M |
| Total current liabilities | 34.06M | 73.72M | 11.73M | 4.23M | 7.54M |
| Current deferred revenue | - | - | 4.66M | 2.52M | 5.47M |
| Net debt | 26.51M | 0.72M | -51.34M | -110.76M | 66.14M |
| Short term debt | 0.84M | 38.24M | 0.48M | 0.36M | 0.72M |
| Short long term debt | - | - | 4.66M | - | 0.39M |
| Short long term debt total | 60.30M | 43.77M | 14.12M | 1.59M | 70.35M |
| Other stockholder equity | 544.32M | 461.68M | 394.26M | 394.14M | 192.06M |
| Property plant equipment | - | - | 1.78M | 2.02M | 2.39M |
| Total current assets | 86.03M | 86.94M | 93.02M | 115.06M | 8.38M |
| Long term investments | 6.01M | - | 20.00M | 15.42M | - |
| Net tangible assets | - | - | 85.81M | 127.12M | -66.41M |
| Short term investments | 35.71M | 24.69M | 17.38M | - | - |
| Net receivables | 10.51M | 17.38M | 8.30M | 1.53M | 2.58M |
| Long term debt | 59.50M | - | 12.80M | - | 68.05M |
| Inventory | 1.97M | 9.84M | - | - | 0.11M |
| Accounts payable | 13.07M | 13.99M | 3.61M | 0.52M | 1.17M |
| Accumulated other comprehensive income | 0.63M | -0.04M | 0.11M | - | - |
| Non currrent assets other | 11.38M | 9.94M | 0.72M | 0.44M | 0.44M |
| Non current assets total | 92.10M | 85.39M | 22.51M | 17.89M | 2.83M |
| Capital lease obligations | 0.79M | - | 1.32M | 1.59M | 1.91M |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Investments | -36.72M | -15.52M | -0.03M | 3.23M | - |
| Change to liabilities | 3.13M | -1.11M | 0.93M | -3.79M | - |
| Total cashflows from investing activities | -36.72M | -15.52M | -0.03M | 3.23M | - |
| Net borrowings | 12.75M | -38.10M | 0.55M | -0.21M | - |
| Total cash from financing activities | 8.35M | 113.11M | 2.74M | 4.94M | 28.02M |
| Change to operating activities | 3.03M | -0.29M | 0.16M | 0.39M | - |
| Net income | -41.54M | -8.55M | -12.76M | -24.52M | -56.47M |
| Change in cash | -46.88M | 108.02M | 0.77M | -15.56M | 7.15M |
| Begin period cash flow | 112.35M | 4.32M | 3.56M | 19.12M | 11.97M |
| End period cash flow | 65.47M | 112.35M | 4.32M | 3.56M | 19.12M |
| Total cash from operating activities | -18.72M | 10.44M | -1.94M | -23.74M | -54.20M |
| Issuance of capital stock | 0.00M | 86.04M | 2.30M | 0.00M | - |
| Depreciation | 0.94M | 0.26M | 0.27M | 0.30M | 0.32M |
| Dividends paid | - | -30.82M | - | - | - |
| Change to inventory | 0.15M | 0.15M | 0.15M | 0.15M | - |
| Change to account receivables | -6.77M | 1.05M | -0.71M | -1.73M | - |
| Sale purchase of stock | -4.72M | -2.81M | - | - | - |
| Other cashflows from financing activities | 13.09M | 98.80M | 0.66M | 5.15M | -0.12M |
| Change to netincome | 22.35M | 18.94M | 7.87M | 3.83M | - |
| Capital expenditures | 0.09M | 0.10M | 0.03M | 0.03M | 0.02M |
| Change in working capital | -0.47M | -0.36M | 0.37M | -5.12M | -2.29M |
| Stock based compensation | 4.29M | 2.44M | 2.49M | 4.41M | 6.50M |
| Other non cash items | 18.05M | 0.46M | 7.25M | 3.19M | 3.71M |
| Free cash flow | -18.81M | 10.34M | -1.97M | -23.76M | -54.22M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| ZVRA Zevra Therapeutics Inc. |
1.06 10.07% |
11.59 | - | 10.70 | 11.67 | 11.54 | 11.65 | -4.24 |
| NVO Novo Nordisk A/S |
0.01 0.02% |
40.31 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
4.59 0.85% |
547.09 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
1.45 0.16% |
904.35 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Zevra Therapeutics, Inc., a commercial-stage company, focuses on addressing unmet needs for the treatment of rare diseases in the United States. The company develops its products through Ligand Activated Technology platform. Its lead product candidate is KP1077, consisting of KP1077IH, which is under Phase 2 clinical trial for the treatment of idiopathic hypersomnia, and KP1077N, which is under Phase 1/2 clinical trial to treat narcolepsy. The company is also developing Celiprolol, a prodrug product candidate that is under Phase 3 clinical trial for the treatment of vascular Ehlers Danlos syndrome. In addition, it offers AZSTARYS, a once-daily treatment for attention deficit and hyperactivity disorder in patients aged six years and older; OLPRUVA to treat urea cycle disorders; and MIPLYFFA for the treatment of niemann pick disease type C, an ultra-rare neurodegenerative lysosomal storage disorder. The company has collaboration and license agreement with Commave Therapeutics SA to develop, manufacture and commercialize the company's product candidates containing SDX and d-methylphenidate; and license agreement with Acer and Relief Therapeutics, Inc. to develop and commercialize rights for OLPRUVA. The company was formerly known as KemPharm, Inc. and changed its name to Zevra Therapeutics, Inc. in February 2023. Zevra Therapeutics, Inc. was incorporated in 2006 and is headquartered in Celebration, Florida.
| Name | Title | Year Born |
|---|---|---|
| Mr. Neil F. McFarlane | President, CEO & Director | 1973 |
| Ms. Christal M. M. Mickle M.A. | Co-Founder & Chief Development Officer | 1979 |
| Mr. R. LaDuane Clifton CPA | CFO, Secretary & Treasurer | 1972 |
| Mr. Joshua M. Schafer M.B.A. | Chief Commercial Officer & Executive VP of Business Development | 1972 |
| Dr. Sven Guenther Ph.D. | Chief Scientific Officer | 1972 |
| Ms. Nichol L. Ochsner | Vice President of Investor Relations & Corporate Communications | NA |
| Dr. Christopher M. Lauderback Ph.D. | Senior Vice President of Manufacturing | 1975 |
| Dr. Rene A. Braeckman Ph.D. | Senior Vice President of Clinical Development | NA |
| Dr. Daniel Gallo Ph.D. | Senior Vice President of Medical Affairs & Advocacy | NA |
| Dr. Adrian Quartel FFPM, M.D. | Chief Medical Officer | 1961 |
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