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Annovis Bio, Inc., a clinical stage drug platform company, develops drugs to treat neurodegeneration in the United States. The company's lead product candidate is Buntanetap, which is in phase 3 to treat alzheimer's disease, as well as in open-label phase 3 to treat parkinson's disease. It also develops ANVS405, which is in phase 2 and 3 clinical trials for the treatment of traumatic brain injury and/or stroke; and ANVS301, which finished phase 1 clinical trial developed to increase cognitive capability in later stages of alzheimer's disease and dementia. Annovis Bio, Inc. was incorporated in 2008 and is headquartered in Malvern, Pennsylvania.
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| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -28.85M | -24.59M | -56.20M | -25.33M | -14.49M |
| Net income | -28.85M | -24.59M | -56.20M | -25.15M | -14.44M |
| Selling general administrative | 4479.65M | 6.70M | 6.24M | 9.00M | 6.06M |
| Selling and marketing expenses | - | 0.10M | 0.10M | - | - |
| Ebit | - | - | -45.04M | - | -14.54M |
| Ebitda | -29.70M | -26.69M | -45.03M | -25.51M | -14.50M |
| Depreciation and amortization | - | - | 0.00M | - | 0.04M |
| Non operating income net other | - | - | - | - | 0.04M |
| Operating income | -29.70M | -26.69M | -45.03M | -25.51M | -14.54M |
| Other operating expenses | 29.70M | 26.69M | 45.03M | 25.51M | 14.50M |
| Interest expense | - | 1.85M | - | -0.18M | 0.01M |
| Interest income | 0.70M | 0.33M | 0.68M | 0.18M | 0.01M |
| Net interest income | 0.70M | -1.52M | 0.68M | 0.18M | 0.01M |
| Income tax expense | - | -24565.78M | -0.05M | -0.18M | -0.05M |
| Total revenue | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 29.70M | 26.69M | 45.03M | 25.51M | 14.50M |
| Total other income expense net | 0.84M | 2.10M | -11.17M | 0.18M | 0.05M |
| Net income from continuing ops | -28.85M | -24.59M | -41.72M | -25.33M | -14.49M |
| Net income applicable to common shares | - | - | - | - | -14.49M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 21.08M | 13.93M | 10.21M | 36.02M | 46.00M |
| Other current assets | -19511.26M | 3.37M | 4.45M | 7644.38M | 315.46M |
| Total liab | 4.23M | 4.62M | 17.96M | 7.70M | 1.51M |
| Total stockholder equity | 16.85M | 9.31M | -7.75M | 28.32M | 44.49M |
| Other current liab | 1.04M | 1.58M | 2.99M | 3.74M | 0.82M |
| Common stock | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Capital stock | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Retained earnings | -163.70M | -134.85M | -110.26M | -54.05M | -28.73M |
| Other assets | 1549.29M | 3373.72M | - | - | - |
| Cash | 19532.34M | 10.55M | 5.75M | 28.38M | 45.69M |
| Total current liabilities | 3.64M | 3.88M | 4.28M | 7.70M | 1.51M |
| Net debt | -19532.34M | -10.55M | -5.75M | -28.38M | -45.69M |
| Other stockholder equity | 180.55M | 144.16M | 102.51M | 82.38M | 73.22M |
| Total current assets | 21.08M | 13.93M | 10.21M | 36.02M | 46.00M |
| Net tangible assets | - | - | - | - | 44.49M |
| Short term investments | - | 10541.36M | - | - | - |
| Accounts payable | 2.59M | 2.31M | 1.29M | 3.96M | 0.69M |
| Common stock total equity | - | - | - | - | 0.00M |
| Retained earnings total equity | - | - | - | - | -28.73M |
| Non currrent assets other | 1549.29M | - | - | - | - |
| Non current assets total | 1549.29M | 13911.71M | 0.00M | 0.00M | 0.00M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Change to liabilities | - | - | - | - | 0.93M |
| Total cash from financing activities | 34600.12M | 26691.80M | 17.34M | 0.00M | 46.74M |
| Change to operating activities | - | - | - | - | 0.31M |
| Net income | -28854.20M | -24590.38M | -56.20M | -25.33M | -14.49M |
| Change in cash | 8980.42M | 4797.20M | -22.62M | -17.31M | 37.61M |
| Begin period cash flow | 10551.92M | 5754.72M | 28.38M | 45.69M | 8.07M |
| End period cash flow | 19532.34M | 10551.92M | 5.75M | 28.38M | 45.69M |
| Total cash from operating activities | -25619.70M | -21894.60M | -39.97M | -17.31M | -9.13M |
| Issuance of capital stock | 34.60M | 18.67M | 8.57M | 0.00M | 46.65M |
| Sale purchase of stock | - | - | - | - | 46.74M |
| Other cashflows from financing activities | 34565.52M | 26673.13M | 0.46M | 0.00M | 0.10M |
| Change to netincome | - | - | - | - | 4.70M |
| Capital expenditures | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Cash flows other operating | - | - | - | - | -0.27M |
| Cash and cash equivalents changes | - | - | - | - | 37.61M |
| Change in working capital | 1.58M | 0.68M | -0.23M | -1.14M | 0.66M |
| Stock based compensation | 1797.68M | 3836.77M | 4.63M | 9.15M | 4.70M |
| Other non cash items | 1435.24M | -1141.68M | 11.84M | - | 14472.64M |
| Free cash flow | -25619.70M | -21894.60M | -39.97M | -17.31M | -9.13M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|
| ANVS Annovis Bio Inc |
0.03 3.91% |
0.88 | - | - | - | 25.18 | -3.57 |
| NVO Novo Nordisk A/S |
0.47 1.18% |
40.78 | 41.58 | 31.15 | 2.13 | 32.99 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
0.34 0.06% |
547.43 | 30.22 | 24.27 | 10.36 | 6.50 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
8.76 0.97% |
913.11 | 29.07 | 20.12 | 7.57 | 3.82 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 36.06 |
Annovis Bio, Inc., a clinical stage drug platform company, develops drugs to treat neurodegeneration in the United States. The company's lead product candidate is Buntanetap, which is in phase 3 to treat alzheimer's disease, as well as in open-label phase 3 to treat parkinson's disease. It also develops ANVS405, which is in phase 2 and 3 clinical trials for the treatment of traumatic brain injury and/or stroke; and ANVS301, which finished phase 1 clinical trial developed to increase cognitive capability in later stages of alzheimer's disease and dementia. Annovis Bio, Inc. was incorporated in 2008 and is headquartered in Malvern, Pennsylvania.
| Name | Title | Year Born |
|---|---|---|
| Dr. Maria L. Maccecchini Ph.D. | Founder, CEO, Pres & Exec. Director | 1951 |
| Mr. Henry Hagopian III, M.B.A. | Chief Financial Officer | 1968 |
| Dr. Cheng Fang Ph.D. | Sr. VP of R&D | NA |
| Ms. Eve M. Damiano M.S., RAC | Sr. VP of Regulatory Operations | NA |
| Dr. Maria L. Maccecchini Ph.D. | Founder, Acting CFO, CEO, President & Executive Director | 1951 |
| Dr. Cheng Fang Ph.D. | Senior Vice President of Research & Development | NA |
| Ms. Eve M. Damiano M.S., RAC | Senior Vice President of Regulatory Operations | NA |
| Mr. Blake Jensen M.B.A. | Head of Quality | NA |
| Ms. Hilda Maibach | Senior Vice President of Statistics | NA |
| Dr. Cheng Fang Ph.D. | Chief Scientific Officer | NA |
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