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Arcturus Therapeutics Holdings Inc., a messenger RNA medicines company, focuses on the development of liver and respiratory rare disease therapeutics. Its technology platforms include STARR, a self-amplifying mRNA technology platform, and LUNAR, a lipid-mediated delivery system. The company also develops ARCT-032 (LUNAR-CF), an mRNA therapeutic candidate for cystic fibrosis that is in Phase 2 clinical development; and ARCT-810 (LUNAR-OTC), which is in Phase 2 clinical development to address ornithine transcarbamylase (OTC) deficiency. In addition, it develops KOSTAIVE, a self-amplifying RNA vaccine for COVID-19; ARCT-2138 (LUNAR-FLU), which is in Phase1 clinical trial for the treatment of seasonal influenza; and ARCT-2304 (LUNAR-H5N1) that is in Phase1 clinical trial for the treatment of Pandemic Influenza. Arcturus Therapeutics Holdings Inc. was founded in 2013 and is headquartered in San Diego, California.
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| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -65.78M | -80.94M | -27.89M | 10.64M | -203.67M |
| Net income | -65.78M | -80.94M | -29.73M | 9.35M | -206.86M |
| Selling general administrative | 46.08M | 52.82M | 52.87M | 46.07M | 41.45M |
| Selling and marketing expenses | - | - | 2.96M | - | - |
| Gross profit | 64.20M | 138.39M | 157.75M | 205.75M | 12.36M |
| Reconciled depreciation | 3.02M | 3.54M | 2.69M | 1.53M | 1.19M |
| Ebit | -74.95M | -80.94M | -27.12M | 12.18M | -202.85M |
| Ebitda | -71.93M | -77.40M | -24.16M | 11.66M | -200.39M |
| Depreciation and amortization | 3.02M | 3.54M | 2.96M | -0.52M | 2.46M |
| Non operating income net other | - | - | - | - | -0.82M |
| Operating income | -74.95M | -95.67M | -78.20M | 12.18M | -202.85M |
| Other operating expenses | 142.18M | 234.06M | 235.95M | 193.58M | 215.21M |
| Interest expense | 0.01M | 0.00M | 0.77M | 0.42M | 2.67M |
| Tax provision | 0.00M | -0.00M | 2.87M | 1.29M | - |
| Interest income | 10.10M | 15.20M | 12.29M | 2.58M | 0.75M |
| Net interest income | 10.10M | 15.20M | 10.73M | -0.42M | -1.92M |
| Income tax expense | -75.88M | -0.00M | 1.83M | 1.29M | 3.19M |
| Total revenue | 67.22M | 138.39M | 157.75M | 205.75M | 12.36M |
| Total operating expenses | 139.15M | 234.06M | 235.95M | 193.58M | 215.21M |
| Cost of revenue | 3.02M | 3.54M | 2.96M | - | - |
| Total other income expense net | 9.17M | 14.72M | 50.31M | -1.53M | -0.82M |
| Net income from continuing ops | -65.78M | -80.94M | 99.33M | 9.35M | -203.67M |
| Net income applicable to common shares | - | - | - | 9.35M | -203.67M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 271.15M | 344.07M | 429.40M | 450.39M | 392.81M |
| Other current assets | 4.97M | 64.98M | 7.52M | 8.69M | 5.10M |
| Total liab | 57.16M | 103.09M | 150.89M | 180.07M | 164.60M |
| Total stockholder equity | 213.99M | 240.98M | 278.51M | 270.31M | 228.21M |
| Deferred long term liab | - | - | - | - | 19.93M |
| Other current liab | 19.68M | 32.81M | 25.06M | 30.23M | 23.52M |
| Common stock | 0.03M | 0.03M | 0.03M | 0.03M | 0.03M |
| Capital stock | 0.03M | 0.03M | 0.03M | 0.03M | 0.03M |
| Retained earnings | -514.59M | -448.81M | -367.87M | -338.14M | -347.49M |
| Other liab | - | - | - | 22.88M | 19.93M |
| Other assets | - | - | - | - | 2.08M |
| Cash | 230.91M | 237.03M | 347.00M | 391.88M | 370.49M |
| Total current liabilities | 36.38M | 65.49M | 81.99M | 126.98M | 99.54M |
| Current deferred revenue | 8.25M | 21.93M | 47.34M | 28.65M | 43.48M |
| Net debt | -205.91M | -208.48M | -316.79M | -301.01M | -302.88M |
| Short term debt | 4.21M | 3.55M | 4.31M | 60.66M | 22.47M |
| Short long term debt | - | - | - | 60.66M | 22.47M |
| Short long term debt total | 25.00M | 28.55M | 30.22M | 90.87M | 67.61M |
| Other stockholder equity | 728.55M | 689.76M | 646.35M | 608.43M | 575.67M |
| Property plant equipment | - | - | - | 44.96M | 11.26M |
| Total current assets | 241.45M | 305.98M | 386.59M | 403.33M | 378.96M |
| Long term investments | - | - | - | 0.00M | 0.52M |
| Net tangible assets | - | - | - | - | 228.21M |
| Net receivables | 5.56M | 3.97M | 32.06M | 2.76M | 3.37M |
| Long term debt | - | - | - | - | 40.63M |
| Inventory | - | - | 0.00M | - | - |
| Accounts payable | 4.24M | 7.19M | 5.28M | 7.45M | 10.06M |
| Common stock total equity | - | - | - | - | 0.03M |
| Retained earnings total equity | - | - | - | - | -347.49M |
| Non currrent assets other | 1.89M | 1.89M | 1.89M | 2.09M | 2.08M |
| Non current assets total | 29.70M | 38.09M | 42.81M | 47.05M | 13.85M |
| Capital lease obligations | 25.00M | 28.55M | 30.22M | 34.10M | 6.04M |
| Long term debt total | - | - | - | - | 40.63M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | - | -0.65M | -5.83M | -7.73M | -3.41M |
| Change to liabilities | - | - | - | 0.00M | 32.02M |
| Total cashflows from investing activities | -0.23M | -0.65M | -2.90M | -7.73M | -3.41M |
| Net borrowings | 0.00M | 0.00M | -27.36M | -5.00M | 46.60M |
| Total cash from financing activities | 13.38M | 5.42M | -24.09M | -2.86M | 48.02M |
| Change to operating activities | - | - | - | - | 0.45M |
| Net income | -65.78M | -80.94M | -29.73M | 9.35M | -203.67M |
| Change in cash | -61.12M | -54.98M | -45.09M | 21.41M | -90.43M |
| Begin period cash flow | 293.91M | 348.89M | 393.98M | 372.57M | 463.00M |
| End period cash flow | 232.79M | 293.91M | 348.89M | 393.98M | 372.57M |
| Total cash from operating activities | -74.27M | -59.75M | -18.10M | 31.99M | -135.04M |
| Issuance of capital stock | 12.27M | 0.68M | 0.61M | 0.41M | 0.52M |
| Depreciation | 3.02M | 3.54M | 2.96M | 1.53M | 1.19M |
| Other cashflows from investing activities | -0.23M | -0.65M | - | - | - |
| Change to inventory | - | - | - | - | 0.45M |
| Change to account receivables | -1.59M | 28.09M | -29.30M | 0.60M | -1.24M |
| Sale purchase of stock | - | - | - | - | 1.42M |
| Other cashflows from financing activities | 13.38M | 4.74M | 2.67M | 1.73M | 47.50M |
| Change to netincome | - | - | - | - | 36.20M |
| Capital expenditures | 0.23M | 0.65M | 2.90M | 7.73M | 3.41M |
| Change receivables | - | - | - | - | -1.24M |
| Cash flows other operating | - | - | - | - | 29.95M |
| Cash and cash equivalents changes | - | - | - | - | -90.43M |
| Change in working capital | -39.20M | -20.81M | 7.38M | -12.56M | 31.23M |
| Stock based compensation | 25.41M | 37.99M | 34.65M | 30.61M | 28.91M |
| Other non cash items | 2.28M | 0.47M | -33.36M | 3.06M | 8.38M |
| Free cash flow | -74.27M | -60.40M | -21.00M | 24.27M | -138.45M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| ARCT Arcturus Therapeutics Holdings Inc |
0.99 10.58% |
10.35 | - | 2.48 | 15.35 | 2.62 | 15.04 | -25.67 |
| NVO Novo Nordisk A/S |
0.01 0.02% |
40.31 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
4.59 0.85% |
547.09 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
1.45 0.16% |
904.35 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Arcturus Therapeutics Holdings Inc., a messenger RNA medicines company, focuses on the development of liver and respiratory rare disease therapeutics. Its technology platforms include STARR, a self-amplifying mRNA technology platform, and LUNAR, a lipid-mediated delivery system. The company also develops ARCT-032 (LUNAR-CF), an mRNA therapeutic candidate for cystic fibrosis that is in Phase 2 clinical development; and ARCT-810 (LUNAR-OTC), which is in Phase 2 clinical development to address ornithine transcarbamylase (OTC) deficiency. In addition, it develops KOSTAIVE, a self-amplifying RNA vaccine for COVID-19; ARCT-2138 (LUNAR-FLU), which is in Phase1 clinical trial for the treatment of seasonal influenza; and ARCT-2304 (LUNAR-H5N1) that is in Phase1 clinical trial for the treatment of Pandemic Influenza. Arcturus Therapeutics Holdings Inc. was founded in 2013 and is headquartered in San Diego, California.
10285 Science Center Drive, San Diego, CA, United States, 92121
858 900 2660
106
| Name | Title | Year Born |
|---|---|---|
| Mr. Joseph E. Payne M.Sc. | Founder, Pres, CEO & Director | 1972 |
| Dr. Padmanabh Chivukula | Founder, Chief Scientific Officer, COO & Sec. | 1979 |
| Mr. Andrew H. Sassine MBA | CFO & Director | 1964 |
| Mr. Lance Kurata | Chief Legal Officer | NA |
| Dr. Steven George Hughes M.B.A., M.D. | Strategic Clinical Advisor & Member of Scientific Advisory Board | 1968 |
| Mr. Keith C. Kummerfeld CPA | VP of Fin. & Corp. Controller | NA |
| Dr. Dushyant B. Varshney Ph.D. | Exec. VP & Chief Technology Officer | NA |
| Mr. Deepankar Roy | Sr. Director of Investor Relations | NA |
| Kyle Gutstadt | Sr. Analyst of Investor & PR | NA |
| Mr. Kevin T. Skol | Sr. VP of Bus. Devel. & Alliance Management | NA |
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