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BioNTech SE, together with its subsidiaries, engages in the development and commercialization of immunotherapies in Germany. The company offers BNT162, an mRNA vaccine for the treatment of SARS-CoV-2 virus. It also develops oncology drugs under Phase III clinical trial, including Gotistobart for metastatic non-small cell lung cancer, Pumitamig for small cell lung cancer and advanced/metastatic triple-negative breast cancer, and Trastuzumab pamirtecan for metastatic breast cancer and epirubicin and cyclophosphamide; and drugs under Phase 2/3 clinical trial, such as BNT113 for human papillomavirus and head and neck squamous cell carcinoma, as well as Pumitamig for metastatic colorectal and non-small cell lung cancer. In addition, the company engages in the development of oncology drugs under Phase II clinical trial comprising BNT116 for advance non-small cell lung cancer, BNT326/YL202 for multiple solid tumors and advanced/metastatic breast cancer, Autogene cevumeran for advance colorectal cancer, and Gotistobart for platinum-resistant ovarian cancer, as well as Pumitamig for glioblastoma, hepatocellular carcinoma, malignant pleural mesothelioma, neuroendocrine neoplasms, and metastatic pancreatic ductal adenocarcinoma. Further, it develops BNT166 which is Phase II clinical trial for mpox virus; and infectious diseases drugs under Phase 1/2 clinical trial, which include BNT162 + BNT161 for SARS-CoV-2 and influenza, BNT164 for tuberculosis, BNT165 for malaria, and BNT166 for mpox. The company was incorporated in 2008 and is headquartered in Mainz, Germany.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
BioNTech SE develops mRNA-based vaccines and immunotherapies and is known for its COVID-19 vaccine co-developed with Pfizer. Long-term growth drivers include its mRNA platform applied to oncology and infectious diseases, a broad clinical pipeline, and manufacturing and partner network. It may attract investors seeking exposure to an established mRNA technology with multiple late-stage programs and global commercialization experience.
Material risks include reliance on COVID-19 vaccine revenue, clinical and regulatory setbacks, strong competition in mRNA and oncology, and manufacturing or pricing pressures.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -1009.33M | -677.70M | 1186.10M | 12954.10M | 15046.40M |
| Minority interest | - | - | - | - | 0.00M |
| Net income | -1091.26M | -665.30M | 930.30M | 9434.40M | 10292.50M |
| Selling general administrative | 588.20M | 531.10M | 495.00M | 484.70M | 278.50M |
| Selling and marketing expenses | 110.00M | 67.90M | 62.70M | 59.50M | 50.40M |
| Gross profit | 2140.16M | 2209.80M | 3219.20M | 12778.60M | 15116.00M |
| Reconciled depreciation | 382.80M | 298.00M | 183.40M | 123.30M | 75.20M |
| Ebit | -623.87M | -665.10M | 972.00M | 12642.70M | 15283.80M |
| Ebitda | -256.17M | -367.10M | 1155.40M | 13096.30M | 14970.70M |
| Depreciation and amortization | 367.69M | 298.00M | 183.40M | 453.60M | -313.10M |
| Operating income | -623.87M | -1314.30M | 690.40M | 12642.70M | 15283.80M |
| Other operating expenses | 3380.50M | 4065.40M | 2914.80M | 4667.90M | 4060.80M |
| Interest expense | 13.64M | 13.16M | 7.74M | 18.90M | 5.40M |
| Tax provision | 85.30M | -12.40M | 255.80M | 3519.70M | 4753.90M |
| Interest income | - | 437.60M | 357.60M | 330.30M | 1.50M |
| Net interest income | -11.10M | 425.00M | 349.70M | 311.40M | -25.80M |
| Income tax expense | 81.93M | -12.40M | 255.80M | 3519.70M | 4753.90M |
| Total revenue | 2756.63M | 2751.10M | 3819.00M | 17310.60M | 18976.70M |
| Total operating expenses | 2764.03M | 3524.10M | 2315.00M | 135.90M | 200.10M |
| Cost of revenue | 616.47M | 541.30M | 599.80M | 4532.00M | 3860.70M |
| Total other income expense net | -385.46M | 636.60M | -67.80M | 311.40M | -237.40M |
| Net income from continuing ops | -1136.10M | -665.30M | 930.30M | 9434.40M | 10292.50M |
| Net income applicable to common shares | - | - | - | - | 10292.50M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 21979.24M | 22529.70M | 23006.30M | 23279.10M | 15830.80M |
| Intangible assets | 1605.32M | 790.40M | 804.10M | 158.50M | 144.60M |
| Other current assets | 210.71M | 212.70M | 280.90M | 271.90M | 64.90M |
| Total liab | 2763.22M | 3118.60M | 2760.40M | 3223.50M | 3937.10M |
| Total stockholder equity | 19216.02M | 19411.10M | 20245.90M | 20055.60M | 11893.70M |
| Deferred long term liab | - | - | - | - | 13.60M |
| Other current liab | 799.96M | 1757.60M | 1335.10M | 2633.40M | 3002.60M |
| Common stock | 258.89M | 248.60M | 248.60M | 248.60M | 246.30M |
| Capital stock | 259.00M | 248.60M | 248.60M | 248.60M | 246.30M |
| Retained earnings | 17954.26M | 19098.00M | 19763.30M | 18833.00M | 9882.90M |
| Other liab | - | - | - | - | 283.90M |
| Good will | 367.74M | 380.60M | 362.50M | 61.20M | 57.80M |
| Other assets | - | - | - | 249.20M | 22.20M |
| Cash | 7672.13M | 9761.90M | 11663.70M | 13875.10M | 1692.70M |
| Total current liabilities | 2141.39M | 2523.20M | 2070.50M | 2950.60M | 3481.60M |
| Current deferred revenue | 754.58M | 294.90M | 353.30M | 77.10M | 189.10M |
| Net debt | -7404.85M | -9507.70M | -11444.60M | -13662.90M | -1391.20M |
| Short term debt | 52.18M | 39.50M | 28.10M | 36.00M | 129.90M |
| Short long term debt | 52.20M | 39.50M | 28.10M | 36.00M | 129.90M |
| Short long term debt total | 267.29M | 254.20M | 219.10M | 212.20M | 301.50M |
| Other stockholder equity | 2464.55M | 1390.00M | 1218.60M | -5.30M | -3.80M |
| Property plant equipment | - | - | - | - | 520.40M |
| Total current assets | 16139.73M | 18803.50M | 19527.30M | 21922.00M | 15072.30M |
| Long term investments | 2554.20M | 1254.00M | 1176.10M | 80.20M | 21.30M |
| Net tangible assets | - | - | - | - | 11699.10M |
| Short term investments | 7161.75M | 7021.70M | 4885.30M | 189.40M | 381.60M |
| Net receivables | 984.48M | 1523.90M | 2339.70M | 7146.00M | 12382.10M |
| Long term debt | 215.20M | 214.70M | 191.00M | 176.20M | 171.60M |
| Inventory | 110.65M | 283.30M | 357.70M | 439.60M | 502.50M |
| Accounts payable | 534.67M | 426.70M | 354.00M | 204.10M | 160.00M |
| Accumulated other comprehensive income | -1461.68M | -1325.50M | -984.60M | 979.30M | 1768.30M |
| Non currrent assets other | 76.97M | 36.10M | 83.40M | 6.50M | 0.80M |
| Non current assets total | 5839.51M | 3726.20M | 3479.00M | 1357.10M | 758.50M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | -1910.30M | -2081.20M | -6954.50M | -35.30M | -566.10M |
| Change to liabilities | - | - | - | - | 1516.10M |
| Total cashflows from investing activities | -2371.07M | -2081.20M | - | - | -566.10M |
| Net borrowings | -50.90M | -45.90M | - | - | -66.70M |
| Total cash from financing activities | -50.81M | -45.90M | -778.60M | -1419.30M | 94.20M |
| Net income | -1091.26M | -677.70M | 1186.10M | 12954.10M | 15046.40M |
| Change in cash | -931.17M | -1901.80M | -2211.40M | 12182.40M | 482.50M |
| Begin period cash flow | 8603.30M | 11663.70M | 13875.10M | 1692.70M | 1210.20M |
| End period cash flow | 7672.13M | 9761.90M | 11663.70M | 13875.10M | 1692.70M |
| Total cash from operating activities | 438.00M | 207.70M | 5371.40M | 13577.40M | 889.70M |
| Issuance of capital stock | - | 0.00M | 0.00M | 110.50M | 160.90M |
| Depreciation | 367.69M | 298.00M | 183.40M | 123.30M | 75.20M |
| Other cashflows from investing activities | - | -164.60M | - | - | - |
| Dividends paid | - | 0.00M | 0.00M | 484.30M | 0.00M |
| Change to inventory | 170.88M | 74.50M | 81.90M | 62.90M | -438.40M |
| Change to account receivables | 1040.93M | 387.70M | 5263.84M | 4369.90M | -11808.10M |
| Sale purchase of stock | 0.00M | 0.00M | -738.50M | -986.40M | 0.00M |
| Other cashflows from financing activities | -39.96M | -43.50M | 0.30M | 0.80M | -566.10M |
| Change to netincome | - | - | - | - | 1252.40M |
| Capital expenditures | 168.19M | 452.30M | 705.50M | 363.30M | 154.00M |
| Change in working capital | 516.57M | 1220.60M | 5574.80M | 4518.50M | -10730.40M |
| Stock based compensation | 106.20M | 100.90M | 51.40M | 108.60M | 93.90M |
| Other non cash items | 574.01M | -734.10M | -1275.50M | -4127.10M | 212.50M |
| Free cash flow | 269.81M | -244.60M | 4665.90M | 13214.10M | 735.70M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| BNTX BioNTech SE |
- -% |
87.51 | - | 7.04 | 9.83 | 1.18 | 2.81 | 32.70 |
| NVO Novo Nordisk A/S |
0.01 0.02% |
40.31 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
4.59 0.85% |
547.09 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
1.45 0.16% |
904.35 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
BioNTech SE, together with its subsidiaries, engages in the development and commercialization of immunotherapies in Germany. The company offers BNT162, an mRNA vaccine for the treatment of SARS-CoV-2 virus. It also develops oncology drugs under Phase III clinical trial, including Gotistobart for metastatic non-small cell lung cancer, Pumitamig for small cell lung cancer and advanced/metastatic triple-negative breast cancer, and Trastuzumab pamirtecan for metastatic breast cancer and epirubicin and cyclophosphamide; and drugs under Phase 2/3 clinical trial, such as BNT113 for human papillomavirus and head and neck squamous cell carcinoma, as well as Pumitamig for metastatic colorectal and non-small cell lung cancer. In addition, the company engages in the development of oncology drugs under Phase II clinical trial comprising BNT116 for advance non-small cell lung cancer, BNT326/YL202 for multiple solid tumors and advanced/metastatic breast cancer, Autogene cevumeran for advance colorectal cancer, and Gotistobart for platinum-resistant ovarian cancer, as well as Pumitamig for glioblastoma, hepatocellular carcinoma, malignant pleural mesothelioma, neuroendocrine neoplasms, and metastatic pancreatic ductal adenocarcinoma. Further, it develops BNT166 which is Phase II clinical trial for mpox virus; and infectious diseases drugs under Phase 1/2 clinical trial, which include BNT162 + BNT161 for SARS-CoV-2 and influenza, BNT164 for tuberculosis, BNT165 for malaria, and BNT166 for mpox. The company was incorporated in 2008 and is headquartered in Mainz, Germany.
| Name | Title | Year Born |
|---|---|---|
| Prof. Ugur Sahin M.D. | Co-Founder, CEO & Chair of the Management Board | 1965 |
| Dr. Ozlem Tureci M.D. | Co-Founder, Chief Medical Officer & Member of Management Board | 1967 |
| Prof. Christoph Hubert Huber M.D., Ph.D. | Co-Founder & Member of Supervisory Board | 1944 |
| Mr. Jens H. Holstein | CFO & Member of Management Board | 1963 |
| Dr. Sierk Poetting Ph.D. | MD, COO & Member of Management Board | 1973 |
| Mr. Ryan Richardson | Chief Strategy Officer, MD & Member of Management Board | 1979 |
| Mr. Sean Marett | Chief Bus. Officer, Chief Commercial Officer & Member of Management Board | 1965 |
| Sylke Maas Ph.D. | VP of Investor Relations and Bus. Strategy | NA |
| Dr. James Timothy Patrick Ryan Ph.D. | Sr. VP & Gen. Counsel | NA |
| Michael Boehler | MD & Head of Global External Communications | NA |
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