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Humanigen, Inc., a clinical-stage biopharmaceutical company, focuses on preventing and treating an immune hyper-response. The company is developing lenzilumab, an antibody that binds to and neutralizes granulocyte-macrophage colony-stimulating factor (GM-CSF), to treat cytokine storm associated with COVID-19 for which it has completed a Phase 3 study and is the focus of a Phase 2/3 study sponsored by the NIH. It is also developing lenzilumab, which is associated with CD19-targeted CAR-T cell therapies, as well as exploring the effectiveness of lenzilumab in other inflammatory conditions, such as acute Graft versus Host Disease in patients undergoing allogeneic hematopoietic stem cell transplantation and in eosinophilic asthma, and rheumatoid arthritis. In addition, the company focuses on studying lenzilumab for patients with chronic myelomonocytic leukemia exhibiting RAS pathway mutations. Its pipeline also includes two other Humaneered monoclonal antibodies, ifabotuzumab, which binds to EphA3, and HGEN005, which targets EMR1, as well as treats a range of eosinophilic diseases, including eosinophilic leukemia as an optimized naked antibody and as the backbone for a novel CAR-T construct. Humanigen, Inc. was incorporated in 2000 and is headquartered in Short Hills, New Jersey.
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| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Income before tax | -70.73M | -236.65M | -89.53M | -10.29M | -12.00M |
| Net income | -70.24M | -238.91M | -90.87M | -11.64M | -12.00M |
| Selling general administrative | 15.61M | 23.25M | 15.80M | 6.33M | 9.11M |
| Gross profit | 2.51M | 3.60M | 0.31M | -2.15M | -1.77M |
| Reconciled depreciation | - | - | - | 0.00M | 0.02M |
| Ebit | -68.30M | -232.77M | -88.20M | -8.94M | -11.01M |
| Ebitda | -67.81M | -234.38M | -88.20M | -8.95M | -10.99M |
| Depreciation and amortization | 0.49M | -1.61M | -0.00M | -0.00M | 0.02M |
| Non operating income net other | - | -1.61M | -0.00M | -0.00M | 0.18M |
| Operating income | -68.30M | -232.77M | -88.20M | -8.94M | -11.33M |
| Other operating expenses | 70.82M | 236.37M | 88.51M | 8.94M | 11.33M |
| Interest expense | 2.92M | 2.26M | 1.34M | 1.35M | 0.85M |
| Net interest income | -2.92M | -2.26M | -1.34M | -1.35M | -0.85M |
| Income tax expense | -0.49M | 2.26M | 1.34M | 1.35M | 0.18M |
| Total revenue | 2.51M | 3.60M | 0.31M | 0.00M | 0.00M |
| Total operating expenses | 70.82M | 236.37M | 88.51M | 8.94M | 11.33M |
| Cost of revenue | - | - | - | 2.15M | 1.77M |
| Total other income expense net | -2.43M | -3.88M | -1.34M | -1.35M | 0.18M |
| Net income from continuing ops | -70.73M | -236.65M | -89.53M | -10.29M | -12.00M |
| Net income applicable to common shares | - | -236.65M | -89.53M | -10.29M | -12.00M |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Total assets | 11.20M | 71.06M | 68.30M | 0.52M | 1.37M |
| Intangible assets | - | - | 0.02M | - | - |
| Other current assets | 0.95M | 0.95M | 0.47M | 0.31M | 0.48M |
| Total liab | 57.96M | 94.75M | 22.76M | 14.84M | 9.48M |
| Total stockholder equity | -46.77M | -23.69M | 45.55M | -14.32M | -8.11M |
| Deferred long term liab | - | 1.02M | 2.34M | - | - |
| Other current liab | 14.79M | 19.88M | 5.46M | 3.31M | 3.13M |
| Common stock | 0.12M | 0.06M | 0.05M | 0.11M | 0.11M |
| Capital stock | 0.12M | 0.06M | 0.05M | 0.11M | 0.11M |
| Retained earnings | -681.81M | -611.08M | -374.43M | -284.89M | -274.60M |
| Other liab | - | 1.02M | 2.34M | - | - |
| Other assets | - | 0.09M | 0.07M | 0.07M | 0.07M |
| Cash | 10.15M | 70.02M | 67.74M | 0.14M | 0.81M |
| Total current liabilities | 56.19M | 68.72M | 20.41M | 13.59M | 8.26M |
| Current deferred revenue | 0.88M | 4.14M | 1.87M | - | - |
| Net debt | -10.15M | -45.01M | -67.74M | 6.34M | 2.68M |
| Short term debt | - | - | 5.24M | 5.24M | 2.28M |
| Short long term debt | - | - | - | 5.24M | 2.28M |
| Short long term debt total | - | 25.01M | - | 6.49M | 3.50M |
| Other stockholder equity | 634.92M | 587.33M | 419.92M | 270.46M | 266.38M |
| Total current assets | 11.11M | 70.97M | 68.21M | 0.45M | 1.30M |
| Net tangible assets | - | -23.69M | 45.52M | -14.32M | -8.11M |
| Long term debt | - | 25.01M | - | 1.25M | 1.22M |
| Accounts payable | 40.52M | 44.70M | 13.08M | 5.05M | 2.86M |
| Common stock total equity | - | 0.06M | 0.05M | 0.11M | 0.11M |
| Retained earnings total equity | - | -611.08M | -374.43M | -284.89M | -274.60M |
| Non currrent assets other | 0.09M | 0.09M | 0.07M | 0.07M | 0.07M |
| Non current assets total | 0.09M | 0.09M | 0.09M | 0.07M | 0.07M |
| Long term debt total | - | 25.01M | - | 1.25M | 1.22M |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Investments | - | 0.00M | -0.02M | - | - |
| Change to liabilities | - | 30.28M | 17.36M | 2.58M | -0.07M |
| Total cashflows from investing activities | - | - | -0.02M | -0.02M | -0.02M |
| Net borrowings | - | 24.44M | -0.83M | 2.82M | 3.48M |
| Total cash from financing activities | 16.84M | 186.32M | 137.47M | 3.33M | 6.26M |
| Change to operating activities | - | 16.39M | 9.16M | 0.56M | 0.45M |
| Net income | -70.73M | -236.65M | -89.53M | -10.29M | -12.00M |
| Change in cash | -59.86M | 2.28M | 67.59M | -0.67M | 0.05M |
| Begin period cash flow | 70.02M | 67.74M | 0.21M | 0.89M | 0.84M |
| End period cash flow | 10.15M | 70.02M | 67.81M | 0.21M | 0.89M |
| Total cash from operating activities | -76.70M | -184.04M | -69.85M | -4.00M | -6.21M |
| Issuance of capital stock | 41.84M | 159.91M | 139.76M | 0.18M | 2.78M |
| Depreciation | - | 0.56M | - | 1.29M | 0.02M |
| Other cashflows from investing activities | - | - | -0.02M | - | - |
| Sale purchase of stock | - | 161.88M | 140.34M | 0.51M | 2.78M |
| Other cashflows from financing activities | - | 26.41M | 1.48M | 3.65M | 3.48M |
| Change to netincome | - | 5.93M | 2.11M | 2.02M | 4.54M |
| Capital expenditures | 0.00M | 0.00M | 0.02M | 0.00M | 0.00M |
| Cash flows other operating | - | -0.48M | 0.21M | 0.40M | 0.49M |
| Cash and cash equivalents changes | - | 2.28M | 67.59M | -0.67M | 0.05M |
| Change in working capital | -11.78M | 46.67M | 17.19M | 2.75M | 0.26M |
| Stock based compensation | 5.81M | 5.37M | 2.11M | 2.02M | 4.81M |
| Other non cash items | - | 0.56M | 0.38M | 1.51M | 0.98M |
| Free cash flow | -76.70M | -184.04M | -69.87M | -4.00M | -6.21M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| NVO Novo Nordisk A/S |
0.01 0.02% |
40.31 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
4.59 0.85% |
547.09 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
1.45 0.16% |
904.35 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Humanigen, Inc., a clinical-stage biopharmaceutical company, focuses on preventing and treating an immune hyper-response. The company is developing lenzilumab, an antibody that binds to and neutralizes granulocyte-macrophage colony-stimulating factor (GM-CSF), to treat cytokine storm associated with COVID-19 for which it has completed a Phase 3 study and is the focus of a Phase 2/3 study sponsored by the NIH. It is also developing lenzilumab, which is associated with CD19-targeted CAR-T cell therapies, as well as exploring the effectiveness of lenzilumab in other inflammatory conditions, such as acute Graft versus Host Disease in patients undergoing allogeneic hematopoietic stem cell transplantation and in eosinophilic asthma, and rheumatoid arthritis. In addition, the company focuses on studying lenzilumab for patients with chronic myelomonocytic leukemia exhibiting RAS pathway mutations. Its pipeline also includes two other Humaneered monoclonal antibodies, ifabotuzumab, which binds to EphA3, and HGEN005, which targets EMR1, as well as treats a range of eosinophilic diseases, including eosinophilic leukemia as an optimized naked antibody and as the backbone for a novel CAR-T construct. Humanigen, Inc. was incorporated in 2000 and is headquartered in Short Hills, New Jersey.
830 Morris Turnpike, Short Hills, NJ, United States, 07078-2625
973 200 3100
6
| Name | Title | Year Born |
|---|---|---|
| Dr. Cameron Durrant M.D., MBA | Chairman, CEO, Principal Financial & Accounting Officer | 1960 |
| Dr. Dale Chappell M.B.A., M.D., MBA | Chief Scientific Officer & Director | 1970 |
| Mr. Robert Atwill M.B.A. | Sr. VP and Head of Asia-Pacific Region & Bus. Devel. | NA |
| Mr. Edward P. Jordan M.B.A. | Chief Commercial Officer | 1968 |
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