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Kazia Therapeutics Limited, together with its subsidiaries, operates as an oncology-focused biotechnology company in South Korea. Its lead development candidate is paxalisib, a small molecule, brain-penetrant inhibitor of the phosphoinositide-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, which is in Phase 3 clinical trial, for the treatment of glioblastoma, isocitrate dehydrogenase-mutant glioma, diffuse intrinsic pontine glioma, atypical teratoid/rhabdoid tumor, brain metastases, primary central nervous system (CNS) lymphoma, triple negative breast cancer, and ovarian cancer. The company also develops EVT801, a small-molecule selective inhibitor of vascular endothelial growth factor receptor 3, which is in Phase 1 clinical trial, to treat advanced solid tumors. It has collaborations with the Australian and New Zealand Children's Haematology/Oncology Group, OIMR Berghofer Medical Research Institute, Genentech Inc., Global Coalition for Adaptive Research, Vivesto AB, Simcere Pharmaceutical Group Ltd, Evotec SE, and Sovargen Co., Ltd. The company was formerly known as Novogen Limited and changed its name to Kazia Therapeutics Limited in November 2017. Kazia Therapeutics Limited was incorporated in 1994 and is based in Sydney, Australia.
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Kazia Therapeutics is a clinical-stage oncology company developing therapies for brain cancers; its lead candidate, paxalisib, is an oral small-molecule PI3K/Akt/mTOR pathway inhibitor designed to cross the blood–brain barrier. Long-term growth drivers include favorable clinical trial outcomes, regulatory approvals, and successful commercialization or licensing of lead programs, which could support broader use in glioblastoma and brain metastases.
Material risks include high clinical and regulatory uncertainty, dependence on a single lead asset, and the likelihood of additional capital raising that could dilute shareholders.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2023-06-30 | 2022-06-30 | 2021-06-30 | 2020-06-30 | 2019-06-30 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2023-06-30 | 2022-06-30 | 2021-06-30 | 2020-06-30 | 2019-06-30 |
| Income before tax | -20.74M | -25.02M | -8.91M | -12.77M | -10.57M |
| Minority interest | - | - | - | - | 0.00M |
| Net income | -20.47M | -24.65M | -8.42M | -12.47M | -10.27M |
| Selling general administrative | 8.58M | 4.51M | 7.02M | 3.69M | 3.79M |
| Selling and marketing expenses | - | 0.13M | - | - | - |
| Gross profit | - | 0.00M | 15.18M | 0.00M | 0.00M |
| Reconciled depreciation | 1.87M | 1.95M | 1.26M | 1.08M | 1.08M |
| Ebit | -24.12M | -26.70M | -3.81M | -12.53M | -8.38M |
| Ebitda | -27.53M | -24.74M | -2.54M | -11.44M | -7.30M |
| Depreciation and amortization | -3.41M | 1.95M | 1.26M | 1.08M | 1.08M |
| Non operating income net other | - | - | - | - | 0.00M |
| Operating income | -24.12M | -26.70M | -3.81M | -12.53M | -8.38M |
| Other operating expenses | 24.15M | 24.88M | 21.56M | 13.16M | 10.25M |
| Interest expense | - | 0.00M | 5.10M | 0.24M | 2.19M |
| Tax provision | -0.27M | -0.37M | -0.48M | -0.30M | -0.30M |
| Interest income | 0.02M | 0.00M | 0.04M | 0.07M | 0.10M |
| Net interest income | 0.02M | 0.00M | 0.04M | 0.07M | 0.10M |
| Extraordinary items | - | - | - | - | 0.00M |
| Non recurring | - | - | - | - | 0.00M |
| Other items | - | - | - | - | 0.00M |
| Income tax expense | -0.27M | -0.37M | -0.48M | -0.30M | -0.30M |
| Total revenue | 0.00M | 0.00M | 15.18M | 0.00M | 0.00M |
| Total operating expenses | 24.15M | 24.88M | 21.56M | 13.16M | 10.25M |
| Cost of revenue | - | - | - | - | 0.00M |
| Total other income expense net | 3.39M | 1.68M | -5.10M | -0.24M | -2.19M |
| Discontinued operations | - | - | - | - | 0.00M |
| Net income from continuing ops | -20.47M | -24.65M | -8.42M | -12.47M | -10.27M |
| Net income applicable to common shares | -20.47M | -24.65M | -8.42M | -12.47M | -10.27M |
| Preferred stock and other adjustments | - | - | - | - | 0.00M |
| Breakdown | 2024-06-30 | 2023-06-30 | 2022-06-30 | 2021-06-30 | 2020-06-30 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2024-06-30 | 2023-06-30 | 2022-06-30 | 2021-06-30 | 2020-06-30 |
| Total assets | 21.59M | 28.09M | 34.96M | 58.09M | 23.06M |
| Intangible assets | 15.40M | 17.27M | 20.05M | 22.00M | 12.41M |
| Other current assets | 0.59M | 3.79M | 0.20M | 1.73M | 0.69M |
| Total liab | 31.60M | 16.03M | 16.32M | 20.24M | 8.94M |
| Total stockholder equity | -10.02M | 12.05M | 18.64M | 37.85M | 14.12M |
| Other current liab | 20.61M | 0.75M | 3.16M | 6.43M | 3.37M |
| Common stock | 101.64M | 97.45M | 84.48M | 80.29M | 48.78M |
| Capital stock | 101.64M | 97.45M | 84.48M | 80.29M | 48.78M |
| Retained earnings | -115.13M | -89.08M | -68.25M | -44.20M | -36.19M |
| Other liab | - | 8.47M | 11.64M | 11.91M | 3.87M |
| Other assets | - | 0.04M | 7.30M | 6.69M | - |
| Cash | 1.66M | 5.24M | 7.36M | 27.59M | 8.76M |
| Total current liabilities | 25.80M | 7.57M | 4.69M | 8.33M | 5.07M |
| Current deferred revenue | - | 4.16M | - | - | - |
| Net debt | -1.02M | -3.44M | -7.36M | -27.59M | -8.76M |
| Short term debt | 0.63M | 1.80M | - | - | - |
| Short long term debt | 0.63M | 1.80M | - | - | - |
| Short long term debt total | 0.63M | 1.80M | - | - | - |
| Other stockholder equity | 0.00M | 4.42M | 0.00M | 0.46M | 0.46M |
| Total current assets | 6.14M | 10.77M | 7.61M | 29.39M | 10.65M |
| Long term investments | - | - | - | - | 0.00M |
| Net tangible assets | - | -5.22M | -1.41M | 15.85M | 1.72M |
| Net receivables | 0.13M | 0.11M | 0.05M | 0.08M | 1.19M |
| Accounts payable | 4.55M | 0.86M | 1.52M | 1.89M | 1.69M |
| Accumulated other comprehensive income | 3.48M | -0.74M | 2.41M | 1.30M | 1.07M |
| Common stock total equity | - | - | - | 80.29M | 48.78M |
| Non currrent assets other | 0.04M | 0.04M | 7.30M | 6.69M | - |
| Non current assets total | 15.44M | 17.31M | 27.35M | 28.70M | 12.41M |
| Breakdown | 2023-06-30 | 2022-06-30 | 2021-06-30 | 2020-06-30 | 2019-06-30 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2023-06-30 | 2022-06-30 | 2021-06-30 | 2020-06-30 | 2019-06-30 |
| Investments | 0.00M | -2.36M | 0.00M | 0.00M | 2.36M |
| Change to liabilities | 0.30M | -1.86M | 0.53M | 1.42M | -0.71M |
| Total cashflows from investing activities | - | -2.36M | -2.36M | -2.36M | 2.36M |
| Net borrowings | - | - | - | - | 0.00M |
| Total cash from financing activities | 12.97M | 3.73M | 28.11M | 12.14M | 3.82M |
| Change to operating activities | 0.58M | 1.76M | -1.09M | -0.11M | 0.37M |
| Net income | -20.46M | -24.65M | -8.42M | -12.47M | -10.27M |
| Change in cash | -2.12M | -20.23M | 18.82M | 3.33M | -0.52M |
| Begin period cash flow | 7.36M | 27.59M | 8.76M | 5.43M | 5.96M |
| End period cash flow | 5.24M | 7.36M | 27.59M | 8.76M | 5.43M |
| Total cash from operating activities | -15.16M | -22.76M | -9.11M | -8.81M | -6.71M |
| Issuance of capital stock | 12.97M | 3.73M | 28.11M | 12.14M | 3.82M |
| Depreciation | 1.87M | 1.95M | 1.26M | 1.08M | 1.08M |
| Other cashflows from investing activities | - | -2.36M | -2.36M | -2.36M | 2.36M |
| Dividends paid | - | - | - | - | 0.00M |
| Change to inventory | - | - | - | - | 0.00M |
| Change to account receivables | 3.45M | -0.01M | -5.03M | 0.36M | 0.82M |
| Sale purchase of stock | - | - | - | - | 3.82M |
| Other cashflows from financing activities | -0.00M | -2.36M | -1.67M | -0.83M | 2.36M |
| Change to netincome | -0.89M | 0.04M | 3.64M | 0.90M | 2.12M |
| Capital expenditures | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Change receivables | - | - | - | - | 0.00M |
| Cash flows other operating | - | - | - | - | 0.00M |
| Exchange rate changes | - | - | - | - | 0.00M |
| Cash and cash equivalents changes | - | - | - | - | 0.00M |
| Change in working capital | 4.33M | -0.10M | -5.59M | 1.67M | 0.35M |
| Stock based compensation | 1.16M | 1.68M | 0.64M | 0.26M | 0.25M |
| Other non cash items | -2.10M | -1.64M | 2.57M | 0.47M | 0.06M |
| Free cash flow | -15.16M | -22.76M | -9.11M | -8.81M | -6.71M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| KZIA Kazia Therapeutics Ltd ADR |
0.03 0.37% |
8.05 | - | - | 1.97 | 3.09 | 2.86 | -0.71 |
| NVO Novo Nordisk A/S |
-0.24 0.61% |
40.20 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-21.28 3.85% |
531.87 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
12.10 1.26% |
973.36 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Kazia Therapeutics Limited, together with its subsidiaries, operates as an oncology-focused biotechnology company in South Korea. Its lead development candidate is paxalisib, a small molecule, brain-penetrant inhibitor of the phosphoinositide-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, which is in Phase 3 clinical trial, for the treatment of glioblastoma, isocitrate dehydrogenase-mutant glioma, diffuse intrinsic pontine glioma, atypical teratoid/rhabdoid tumor, brain metastases, primary central nervous system (CNS) lymphoma, triple negative breast cancer, and ovarian cancer. The company also develops EVT801, a small-molecule selective inhibitor of vascular endothelial growth factor receptor 3, which is in Phase 1 clinical trial, to treat advanced solid tumors. It has collaborations with the Australian and New Zealand Children's Haematology/Oncology Group, OIMR Berghofer Medical Research Institute, Genentech Inc., Global Coalition for Adaptive Research, Vivesto AB, Simcere Pharmaceutical Group Ltd, Evotec SE, and Sovargen Co., Ltd. The company was formerly known as Novogen Limited and changed its name to Kazia Therapeutics Limited in November 2017. Kazia Therapeutics Limited was incorporated in 1994 and is based in Sydney, Australia.
Three International Towers, Sydney, NSW, Australia, 2000
61 2 9472 4101
| Name | Title | Year Born |
|---|---|---|
| Dr. James Garner M.A.I.C.D., M.B.A., B.Sc., M.A., MBA, MBBS, B.Sc ( | CEO, MD & Exec. Director | 1973 |
| Ms. Karen R. Krumeich | Chief Financial Officer | 1954 |
| Dr. John E. Friend II, M.D. | Chief Medical Officer | 1970 |
| Ms. Catherine Jane Hill ACA, B.Sc., BSc (Hons), C.A., GAICD | Company Sec. | 1959 |
| Dr. John Edwin Friend II, M.D. | CEO, MD & Director | 1970 |
| Ms. Gabrielle Heaton BBUS (ACC), CPA | Principal Accounting Officer, VP of Finance & Administration and Principal Financial Officer | NA |
| Ms. Anna Sandham | Company Secretary | NA |
| Ms. Elissa C. Hansen ACSA, B.Com., B.Comm, FCIS, Gad Dip ACG, GAI, GAIC | Company Secretary | 1973 |
| Mr. Jeffrey Bonacorda | VP of Finance & Controller | NA |
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