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aTyr Pharma, Inc., a biotherapeutics company, engages in the discovery and development of medicines based on novel immunological pathways in the United States. Its lead therapeutic candidate is efzofitimod, a selective modulator of NRP2 that is in Phase III clinical trial for pulmonary sarcoidosis; and in Phase 1b/2a clinical trial for treatment of other interstitial lung diseases (ILDs), such as chronic hypersensitivity pneumonitis and connective tissue disease related ILD. The company is developing ATYR0101, a fusion protein derived from a domain of aspartyl-tRNA synthetase that is in preclinical development for the treatment of fibrosis; and ATYR0750, a domain of alanyl-tRNA synthetase for the treatment of liver disorders. It has collaboration and license agreement with Kyorin Pharmaceutical Co., Ltd. for the development and commercialization of efzofitimod for ILDs in Japan. aTyr Pharma, Inc. was incorporated in 2005 and is headquartered in San Diego, California.
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| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Income before tax | -45.34M | -33.78M | -16.23M | -23.76M | -34.52M |
| Minority interest | 0.01M | 0.01M | -0.17M | -0.16M | -0.16M |
| Net income | -44.28M | -32.46M | -14.96M | -22.24M | -34.52M |
| Selling general administrative | 13.98M | 10.75M | 9.07M | 9.35M | 12.44M |
| Gross profit | 10.39M | - | 10.46M | 0.42M | 0.00M |
| Reconciled depreciation | 1.70M | 1.30M | 1.27M | 1.37M | 0.75M |
| Ebit | -48.10M | -35.32M | -17.18M | -24.34M | -33.57M |
| Ebitda | -46.40M | -34.02M | -15.91M | -22.98M | -32.82M |
| Depreciation and amortization | 1.70M | 1.30M | 1.27M | 1.37M | 0.75M |
| Operating income | -46.40M | -34.02M | -15.91M | -22.98M | -32.82M |
| Other operating expenses | 56.79M | 34.02M | 26.37M | 23.40M | 32.82M |
| Interest expense | -1.70M | 0.24M | 0.00M | 0.00M | 0.00M |
| Tax provision | - | - | - | - | 0.00M |
| Income tax expense | -1.07M | -1.31M | -1.27M | -1.53M | -1.70M |
| Total revenue | 10.39M | 0.01M | 10.46M | 0.42M | 0.00M |
| Total operating expenses | 56.79M | 34.02M | 26.37M | 23.40M | 32.82M |
| Cost of revenue | - | - | - | - | 0.00M |
| Total other income expense net | 1.06M | 0.24M | -0.32M | -0.79M | -1.70M |
| Net income from continuing ops | -45.34M | -33.78M | -16.23M | -23.76M | -34.52M |
| Net income applicable to common shares | -45.34M | -33.77M | -16.22M | -23.60M | -34.52M |
| Breakdown | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Total assets | 122.07M | 95.79M | 115.54M | 38.73M | 36.19M |
| Other current assets | 2.39M | 2.95M | 5.38M | 2.02M | 0.78M |
| Total liab | 31.60M | 24.50M | 6.41M | 7.24M | 15.16M |
| Total stockholder equity | 90.66M | 71.28M | 109.13M | 31.48M | 21.03M |
| Other current liab | 23.12M | 9.86M | 4.00M | 3.57M | 2.38M |
| Common stock | 0.06M | 0.03M | 0.03M | 0.01M | 0.00M |
| Capital stock | 0.06M | 0.03M | 0.03M | 0.01M | 0.01M |
| Retained earnings | -468.02M | -417.63M | -372.30M | -338.53M | -322.30M |
| Other assets | 0.00M | 3.36M | 0.16M | 0.00M | 0.17M |
| Cash | 22.54M | 9.98M | 2.34M | 16.95M | 9.21M |
| Total current liabilities | 16.42M | 13.86M | 6.01M | 5.86M | 12.92M |
| Current deferred revenue | -11.56M | - | - | - | 0.21M |
| Net debt | -7.45M | 1.55M | -0.96M | -14.71M | -6.22M |
| Short term debt | 1.33M | 0.89M | 0.98M | 0.86M | 9.49M |
| Short long term debt | - | - | - | - | 8.74M |
| Short long term debt total | 15.10M | 11.53M | 1.38M | 2.24M | 2.99M |
| Other stockholder equity | 558.69M | 489.32M | 481.66M | 370.04M | 343.36M |
| Property plant equipment | - | 11.56M | 1.81M | 2.98M | 4.09M |
| Total current assets | 102.99M | 81.09M | 113.73M | 35.74M | 31.93M |
| Net tangible assets | - | 71.46M | 109.13M | 31.65M | 21.18M |
| Short term investments | 75.62M | 56.16M | 105.58M | 14.74M | 21.93M |
| Net receivables | 2.44M | 11.78M | 0.43M | 2.04M | 0.10M |
| Inventory | -78.01M | -2.95M | - | - | - |
| Accounts payable | 3.53M | 3.11M | 1.03M | 1.43M | 0.85M |
| Accumulated other comprehensive income | -0.07M | -0.43M | -0.26M | -0.04M | -0.04M |
| Common stock total equity | - | - | - | 0.01M | 0.00M |
| Non currrent assets other | 0.13M | 3.14M | 0.16M | 0.21M | 0.17M |
| Non current assets total | 19.07M | 14.70M | 1.81M | 2.98M | 4.26M |
| Capital lease obligations | 15.10M | 11.53M | 1.38M | 2.24M | 2.99M |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Investments | 47.24M | -91.42M | 6.90M | 4.92M | 37.17M |
| Change to liabilities | 6.74M | 0.05M | 1.55M | 0.37M | -2.06M |
| Total cashflows from investing activities | 47.24M | -91.57M | 6.90M | 4.92M | 37.17M |
| Net borrowings | -0.07M | -0.07M | -9.08M | -8.00M | -4.67M |
| Total cash from financing activities | 5.45M | 110.03M | 16.14M | 1.34M | -4.24M |
| Change to operating activities | 4.35M | -4.24M | -1.88M | -0.22M | 0.66M |
| Net income | -45.34M | -33.78M | -16.23M | -23.76M | -34.52M |
| Change in cash | 10.81M | -14.62M | 7.74M | -13.75M | 1.87M |
| Begin period cash flow | 2.34M | 16.95M | 9.21M | 22.96M | 21.09M |
| End period cash flow | 13.15M | 2.34M | 16.95M | 9.21M | 22.96M |
| Total cash from operating activities | -41.89M | -33.08M | -15.30M | -20.01M | -31.06M |
| Issuance of capital stock | 5.47M | 109.95M | 25.22M | 9.32M | 0.38M |
| Depreciation | 1.70M | 1.30M | 1.27M | 1.37M | 0.75M |
| Other cashflows from investing activities | - | - | - | 5.00M | 37.77M |
| Dividends paid | - | - | -0.01M | -0.01M | 0.04M |
| Change to account receivables | -11.92M | 1.60M | -1.94M | 0.06M | -0.05M |
| Sale purchase of stock | 0.04M | - | 0.01M | 0.01M | 0.04M |
| Other cashflows from financing activities | 0.00M | 0.07M | 0.01M | 0.01M | 0.05M |
| Change to netincome | 2.59M | 1.98M | 1.57M | 1.31M | 3.19M |
| Capital expenditures | 1.64M | 0.19M | 0.20M | 0.08M | 0.59M |
| Change in working capital | -0.83M | -2.59M | -2.26M | 0.21M | -1.45M |
| Stock based compensation | 2.15M | 1.61M | 1.47M | 1.78M | 3.43M |
| Other non cash items | 0.44M | 0.37M | 0.35M | 0.71M | 0.97M |
| Free cash flow | -43.53M | -33.27M | -15.50M | -20.09M | -31.66M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| LIFE Ethos Technologies Inc. Class A Common Stock |
-3.75 9.17% |
37.13 | - | - | 334.89 | 1.30 | 99.56 | -0.67 |
| NVO Novo Nordisk A/S |
1.99 4.95% |
42.18 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
18.28 3.44% |
549.04 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
-41.91 4.31% |
931.45 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
aTyr Pharma, Inc., a biotherapeutics company, engages in the discovery and development of medicines based on novel immunological pathways in the United States. Its lead therapeutic candidate is efzofitimod, a selective modulator of NRP2 that is in Phase III clinical trial for pulmonary sarcoidosis; and in Phase 1b/2a clinical trial for treatment of other interstitial lung diseases (ILDs), such as chronic hypersensitivity pneumonitis and connective tissue disease related ILD. The company is developing ATYR0101, a fusion protein derived from a domain of aspartyl-tRNA synthetase that is in preclinical development for the treatment of fibrosis; and ATYR0750, a domain of alanyl-tRNA synthetase for the treatment of liver disorders. It has collaboration and license agreement with Kyorin Pharmaceutical Co., Ltd. for the development and commercialization of efzofitimod for ILDs in Japan. aTyr Pharma, Inc. was incorporated in 2005 and is headquartered in San Diego, California.
10240 Sorrento Valley Road, San Diego, CA, United States, 92121
858 731 8389
56
| Name | Title | Year Born |
|---|---|---|
| Dr. Sanjay S. Shukla M.D., M.S. | Pres, CEO & Director | 1972 |
| Ms. Jill M. Broadfoot | Chief Financial Officer | 1962 |
| Ms. Nancy E. Denyes Krueger | Gen. Counsel & Corp. Sec. | 1968 |
| Xiang-Lei Yang Ph.D. | Founder | NA |
| Ms. Ashlee Dunston | Director of Investor Relations & Corp. Communications | NA |
| Mr. Peter Villiger | VP of Corp. Devel. | NA |
| Ms. Danielle Campbell | VP of Human Resource | NA |
| Dr. Leslie Nangle Ph.D. | VP of Research | NA |
| Dr. Ying J. Buechler Ph.D. | Exec. Director of Biologics Devel. & Manufacturing | NA |
| Dr. Melissa A. Ashlock | Sr. Advisor | 1958 |
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