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MBX Biosciences, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of precision peptide therapies for the treatment of endocrine and metabolic disorders. Its lead product candidate is Canvuparatide (MBX 2109), a parathyroid hormone peptide prodrug, which is in Phase 3 clinical trial for the treatment of chronic hypoparathyroidism. The company is also developing Imapextide (MBX 1416), a long-acting glucagon-like peptide-1 (GLP-1) receptor antagonist that is in Phase 2 clinical trial a potential therapy for post-bariatric hypoglycemia, a chronic complication of bariatric surgery. In addition, it is developing MBX 4291, a lead obesity product candidate, which is in investigational new drug-enabling studies for the treatment of obesity and co-morbidities. The company was founded in 2018 and is based in Carmel, Indiana.
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| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
| Income before tax | -86.97M | -61.92M | -32.56M | -26.14M |
| Net income | -86.97M | -61.92M | -32.56M | -26.14M |
| Selling general administrative | 18.90M | 10.78M | 6.78M | 3.76M |
| Gross profit | -0.25M | -0.24M | -0.16M | -0.06M |
| Reconciled depreciation | 0.25M | 0.24M | 0.16M | 0.06M |
| Ebit | -86.97M | -61.92M | -32.56M | -25.76M |
| Ebitda | -86.72M | -61.68M | -32.41M | -25.70M |
| Depreciation and amortization | 0.25M | 0.24M | 0.16M | 0.06M |
| Operating income | -98.06M | -68.19M | -35.31M | -25.16M |
| Other operating expenses | 98.06M | 68.19M | 35.31M | 25.16M |
| Interest expense | - | - | 0.00M | 0.37M |
| Interest income | 11.08M | 6.27M | 2.75M | 0.37M |
| Net interest income | 11.08M | 6.27M | 2.75M | -0.00M |
| Total revenue | 0.00M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 98.06M | 68.19M | 35.31M | 25.16M |
| Cost of revenue | 0.25M | 0.24M | 0.16M | 0.06M |
| Total other income expense net | 11.08M | 6.27M | 2.75M | -0.97M |
| Net income from continuing ops | -86.97M | -61.92M | -32.56M | -26.14M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
| Total assets | 385.14M | 268.54M | 84.18M | 45.09M |
| Other current assets | 5.71M | 4.46M | 2.58M | 1.61M |
| Total liab | 15.92M | 11.09M | 156.65M | 87.70M |
| Total stockholder equity | 369.22M | 257.44M | -72.47M | -42.60M |
| Other current liab | 12.35M | 5.54M | 2.38M | 2.32M |
| Common stock | 0.01M | 0.01M | 0.00M | 0.00M |
| Capital stock | 0.01M | 0.01M | 0.00M | 0.00M |
| Retained earnings | -224.48M | -137.50M | -75.58M | -43.02M |
| Cash | 75.29M | 49.35M | 30.52M | 24.21M |
| Total current liabilities | 15.49M | 11.05M | 3.93M | 3.43M |
| Net debt | -74.69M | -49.18M | -30.20M | -23.75M |
| Short term debt | 0.17M | 0.17M | 0.15M | 0.14M |
| Short long term debt total | 0.60M | 0.17M | 0.32M | 0.46M |
| Other stockholder equity | 593.41M | 394.89M | 3.05M | 0.41M |
| Total current assets | 381.54M | 267.29M | 83.47M | 44.21M |
| Short term investments | 298.42M | 212.80M | 50.15M | 18.25M |
| Net receivables | 2.12M | 0.68M | 0.21M | 0.14M |
| Accounts payable | 2.98M | 5.33M | 1.39M | 0.98M |
| Accumulated other comprehensive income | 0.29M | 0.06M | 0.06M | 0.00M |
| Non currrent assets other | 0.38M | 0.05M | 0.05M | 0.04M |
| Non current assets total | 3.60M | 1.25M | 0.71M | 0.88M |
| Capital lease obligations | 0.60M | 0.17M | 0.32M | 0.46M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
| Investments | -81.78M | -160.59M | -30.93M | -11.41M |
| Total cashflows from investing activities | -83.70M | -160.59M | -30.93M | -11.41M |
| Net borrowings | - | - | 0.00M | 10.00M |
| Total cash from financing activities | 189.59M | 234.10M | 69.22M | 46.06M |
| Net income | -86.97M | -61.92M | -32.56M | -26.14M |
| Change in cash | 25.94M | 18.83M | 6.31M | 11.53M |
| Begin period cash flow | 49.35M | 30.52M | 24.21M | 12.68M |
| End period cash flow | 75.29M | 49.35M | 30.52M | 24.21M |
| Total cash from operating activities | -79.95M | -54.68M | -31.98M | -23.12M |
| Issuance of capital stock | 187.95M | 238.04M | 68.51M | 36.49M |
| Depreciation | -3.61M | 0.24M | 0.16M | 0.06M |
| Other cashflows from investing activities | 8.50M | - | - | - |
| Other cashflows from financing activities | 189.59M | 59.56M | 68.48M | 36.06M |
| Capital expenditures | 1.93M | 0.87M | 0.13M | 0.44M |
| Change in working capital | 1.57M | 4.60M | -0.73M | 1.29M |
| Stock based compensation | 8.68M | 5.22M | 2.04M | 0.31M |
| Other non cash items | 0.38M | -2.82M | -0.88M | 1.36M |
| Free cash flow | -81.88M | -55.55M | -32.11M | -23.56M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
|---|---|---|---|---|---|---|
| MBX MBX Biosciences, Inc. Common Stock |
2.63 5.12% |
53.98 | - | - | - | 7.00 |
| NVO Novo Nordisk A/S |
0.47 1.18% |
40.78 | 41.58 | 31.15 | 2.13 | 32.99 |
| VRTX Vertex Pharmaceuticals Inc |
0.34 0.06% |
547.43 | 30.22 | 24.27 | 10.36 | 6.50 |
| REGN Regeneron Pharmaceuticals Inc |
8.76 0.97% |
913.11 | 29.07 | 20.12 | 7.57 | 3.82 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 |
MBX Biosciences, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of precision peptide therapies for the treatment of endocrine and metabolic disorders. Its lead product candidate is Canvuparatide (MBX 2109), a parathyroid hormone peptide prodrug, which is in Phase 3 clinical trial for the treatment of chronic hypoparathyroidism. The company is also developing Imapextide (MBX 1416), a long-acting glucagon-like peptide-1 (GLP-1) receptor antagonist that is in Phase 2 clinical trial a potential therapy for post-bariatric hypoglycemia, a chronic complication of bariatric surgery. In addition, it is developing MBX 4291, a lead obesity product candidate, which is in investigational new drug-enabling studies for the treatment of obesity and co-morbidities. The company was founded in 2018 and is based in Carmel, Indiana.
| Name | Title | Year Born |
|---|---|---|
| Mr. Steven L. Hoerter | Executive Chairperson, CEO & President | 1971 |
| Dr. Salomon Azoulay M.D. | Chief Medical Officer | 1958 |
| Mr. John W. Smither CPA | Chief Financial Officer | 1953 |
| Mr. Pete De Spain | Senior Vice President of Investor Relations & Corporate Communications | NA |
| Ms. Michelle Graham | Chief Human Resources Officer | 1967 |
| Dr. Michael A. Dorato DABT, Ph.D. | Sr. Vice President of Discovery & Non-Clinical Development | NA |
| Dr. Chatan Charan Ph.D. | Senior VP of Pharmaceutical Development & Chemistry, Manufacturing and Controls | NA |
| Mr. Mark Hope | Senior Vice President of Regulatory & Quality | NA |
| Dr. Andreas Moraitis M.D. | Senior Vice President of Clinical Development | NA |
| Ms. Karen Basbaum M.B.A. | Chief Business Officer | NA |
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