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Omeros Corporation, a clinical-stage biopharmaceutical company, discovers, develops, and commercializes small-molecule and protein therapeutics, and orphan indications targeting immunologic diseases. The company's lead products candidate is the Narsoplimab (OMS721/MASP-2) for the treatment of hematopoietic stem-cell transplant-associated thrombotic microangiopathy (TA-TMA); and in Phase II clinical trial to treat COVID-19 and acute respiratory distress syndrome. It also develops OMS1029 that has completed phase I clinical trials for mannan-binding lectin-associated serine protease 2 (MASP-2) and lectin pathway disorders; and OMS527 that is in phase I clinical trials for addictions and compulsive disorders, and movement disorders, as well as cocaine use disorder. In addition, the company's products under preclinical development comprise MASP-2, a pro-inflammatory protein target for the treatment of lectin pathway disorders; MASP-3 small-molecule inhibitors for alternative pathway disorders; OncotoX-AML, to treat acute myeloid leukemia; and Targeted Complement Activating Therapy, for Multidrug-resistant organisms. Omeros Corporation was incorporated in 1994 and is headquartered in Seattle, Washington.
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| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -2.80M | -182.63M | -174.92M | -182.03M | -191.55M |
| Net income | -3.35M | -156.81M | -117.81M | 28.78M | 194.24M |
| Selling general administrative | 41.50M | 49.73M | 49.66M | 50.67M | 54.84M |
| Gross profit | - | -0.95M | -69.78M | - | 0.00M |
| Reconciled depreciation | 0.96M | 0.95M | 0.88M | 0.95M | 1.39M |
| Ebit | -2.80M | -157.95M | -144.08M | -163.39M | -173.62M |
| Ebitda | -1.83M | -157.00M | -143.16M | -159.33M | -171.88M |
| Depreciation and amortization | 0.96M | 0.95M | 0.92M | 4.06M | 1.74M |
| Non operating income net other | - | - | - | 4.06M | 1.74M |
| Operating income | -122.80M | -169.26M | -164.53M | -163.39M | -173.62M |
| Other operating expenses | 122.80M | 169.26M | 164.53M | 163.39M | 173.62M |
| Interest expense | 0.96M | 24.68M | 30.84M | 22.70M | 19.67M |
| Tax provision | 2.01M | 2.31M | 0.00M | 0.00M | 0.00M |
| Interest income | 5.06M | 11.30M | 14.91M | 4.06M | - |
| Net interest income | 5.06M | -13.37M | -16.78M | -18.64M | -19.67M |
| Income tax expense | 2.01M | 25.81M | -57.11M | -210.81M | -365.76M |
| Total revenue | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 122.80M | 169.26M | 164.53M | 163.39M | 173.62M |
| Cost of revenue | - | 0.95M | 69.78M | - | 0.00M |
| Total other income expense net | 120.00M | -13.37M | -10.39M | -18.64M | -17.93M |
| Discontinued operations | - | - | - | 229.45M | 385.78M |
| Net income from continuing ops | -4.81M | -182.63M | -181.68M | -182.03M | -191.55M |
| Net income applicable to common shares | - | - | - | 47.42M | 194.24M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 325.63M | 277.08M | 378.27M | 590.97M | 419.27M |
| Other current assets | 7.59M | 7.17M | 8.58M | 6.30M | 8.15M |
| Total liab | 446.86M | 459.69M | 403.25M | 505.29M | 395.49M |
| Total stockholder equity | -121.23M | -182.61M | -24.98M | 85.68M | 23.78M |
| Other current liab | 47.46M | 46.65M | 31.87M | 32.00M | 33.13M |
| Common stock | 0.72M | 0.58M | 0.61M | 721.40M | 0.63M |
| Capital stock | 0.72M | 0.58M | - | 0.63M | 0.63M |
| Retained earnings | -913.70M | -910.35M | -753.53M | -635.72M | -683.13M |
| Other liab | - | - | - | 0.44M | 1.11M |
| Other assets | - | - | - | 124.48M | 141.37M |
| Cash | 9.66M | 3.40M | 7.11M | 11.01M | 100.81M |
| Total current liabilities | 78.06M | 79.53M | 53.32M | 136.68M | 51.79M |
| Current deferred revenue | 2.47M | - | - | - | - |
| Net debt | 229.48M | 203.62M | 354.48M | 331.01M | 247.03M |
| Short term debt | 23.36M | 26.97M | 13.74M | 98.69M | 5.25M |
| Short long term debt | 17.06M | 21.00M | - | 94.38M | - |
| Short long term debt total | 239.14M | 207.02M | 361.58M | 342.02M | 347.84M |
| Other stockholder equity | 791.75M | 727.16M | 727.94M | 720.77M | 706.29M |
| Property plant equipment | - | - | - | 23.25M | 30.01M |
| Total current assets | 215.67M | 134.12M | 217.90M | 443.24M | 247.89M |
| Net tangible assets | - | - | - | 233.24M | 52.91M |
| Short term investments | 162.14M | 86.73M | 164.74M | 183.91M | 56.46M |
| Net receivables | 36.27M | 36.82M | 37.47M | 242.02M | 82.47M |
| Long term debt | 208.53M | 166.58M | - | 220.91M | 313.46M |
| Accounts payable | 4.76M | 5.91M | 7.71M | 5.99M | 13.40M |
| Accumulated other comprehensive income | - | - | 0.00M | - | - |
| Common stock total equity | - | - | - | 0.63M | 0.63M |
| Retained earnings total equity | - | - | - | -635.72M | -683.13M |
| Non currrent assets other | 97.49M | 125.32M | 139.79M | 124.48M | 141.37M |
| Non current assets total | 109.97M | 142.96M | 160.37M | 147.73M | 171.38M |
| Capital lease obligations | 13.54M | 19.44M | - | 26.74M | 34.38M |
| Long term debt total | - | - | - | 220.91M | 313.46M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | -75.41M | 82.22M | -197.28M | -127.45M | 67.99M |
| Change to liabilities | - | - | - | -10.66M | 15.31M |
| Total cashflows from investing activities | 164.52M | 82.22M | 27.45M | -127.56M | 193.71M |
| Net borrowings | -89.16M | -41.34M | -101.58M | 0.04M | 0.29M |
| Total cash from financing activities | -42.17M | 62.88M | -106.08M | 124.25M | 6.32M |
| Change to operating activities | - | - | - | 66.76M | 5.57M |
| Net income | -3.35M | -156.81M | -117.81M | 47.42M | 194.24M |
| Change in cash | 6.26M | -3.71M | -3.90M | -89.80M | 90.31M |
| Begin period cash flow | 3.40M | 7.11M | 11.01M | 100.81M | 10.50M |
| End period cash flow | 9.66M | 3.40M | 7.11M | 11.01M | 100.81M |
| Total cash from operating activities | -116.09M | -148.80M | 74.73M | -86.48M | -109.72M |
| Issuance of capital stock | 39.34M | 0.00M | 0.00M | 0.00M | 0.00M |
| Depreciation | 0.96M | 0.95M | 0.92M | 0.95M | 1.39M |
| Other cashflows from investing activities | 240.00M | - | - | - | 125.99M |
| Change to inventory | - | - | - | - | 34.31M |
| Change to account receivables | 30.45M | 40.01M | 245.72M | -175.07M | -34.31M |
| Sale purchase of stock | 0.00M | -11.85M | -4.65M | 0.41M | 8.14M |
| Other cashflows from financing activities | -42.17M | 116.07M | 0.15M | 125.00M | 8.14M |
| Change to netincome | - | - | - | 14.07M | -292.93M |
| Capital expenditures | 0.07M | 0.17M | 0.43M | 0.11M | 0.28M |
| Change receivables | - | - | - | -175.07M | -34.31M |
| Cash flows other operating | - | - | - | 34.98M | 4.90M |
| Cash and cash equivalents changes | - | - | - | -89.80M | 90.31M |
| Change in working capital | 33.72M | 29.74M | 247.42M | -118.97M | -14.11M |
| Stock based compensation | 8.19M | 10.49M | 11.65M | 14.07M | 17.63M |
| Other non cash items | -155.62M | -33.17M | -67.45M | -29.96M | 1.70M |
| Free cash flow | -116.16M | -148.97M | 74.30M | -86.60M | -110.00M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| OMER Omeros Corporation |
0.56 3.31% |
17.48 | 10.41 | 72.99 | 32.35 | 8.44 | 33.07 | 135.92 |
| NVO Novo Nordisk A/S |
0.47 1.18% |
40.78 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
0.34 0.06% |
547.43 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
8.76 0.97% |
913.11 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Omeros Corporation, a clinical-stage biopharmaceutical company, discovers, develops, and commercializes small-molecule and protein therapeutics, and orphan indications targeting immunologic diseases. The company's lead products candidate is the Narsoplimab (OMS721/MASP-2) for the treatment of hematopoietic stem-cell transplant-associated thrombotic microangiopathy (TA-TMA); and in Phase II clinical trial to treat COVID-19 and acute respiratory distress syndrome. It also develops OMS1029 that has completed phase I clinical trials for mannan-binding lectin-associated serine protease 2 (MASP-2) and lectin pathway disorders; and OMS527 that is in phase I clinical trials for addictions and compulsive disorders, and movement disorders, as well as cocaine use disorder. In addition, the company's products under preclinical development comprise MASP-2, a pro-inflammatory protein target for the treatment of lectin pathway disorders; MASP-3 small-molecule inhibitors for alternative pathway disorders; OncotoX-AML, to treat acute myeloid leukemia; and Targeted Complement Activating Therapy, for Multidrug-resistant organisms. Omeros Corporation was incorporated in 1994 and is headquartered in Seattle, Washington.
| Name | Title | Year Born |
|---|---|---|
| Dr. Gregory A. Demopulos M.D. | Co-Founder, Chairman, CEO & Pres | 1959 |
| Mr. Michael A. Jacobsen | Chief Accounting Officer, VP of Fin. & Treasurer | 1958 |
| Mr. Peter B. Cancelmo J.D. | VP, Gen. Counsel & Corp. Sec. | 1979 |
| Dr. Pamela Pierce Palmer M.D., Ph.D. | Co-Founder | 1963 |
| Dr. George A. Gaitanaris M.D., Ph.D. | Chief Scientific Officer & VP of Science | 1957 |
| Mr. Peter W. Williams | VP of HR | 1968 |
| Dr. J. Steven Whitaker J.D., M.D. | VP of Clinical Devel. & Chief Medical Officer | 1956 |
| Dr. Catherine A. Melfi Ph.D. | Chief Regulatory Officer & VP of Regulatory Affairs and Quality Systems | 1959 |
| Ms. Nadia Dac | VP & Chief Commercial Officer | 1970 |
| Ms. Debra K. Bowes M.T | Chief Bus. Devel. Officer | NA |
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