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Viridian Therapeutics, Inc. engages in discovering, developing, and commercializing treatments for serious and rare diseases. It develops IGF-1R therapies to treat thyroid eye disease (TED), including Veligrotrug, a differentiated humanized monoclonal antibody targeting IGF-1R intravenously administered, and Elegrobart, a low-volume, infrequently dosed subcutaneous IGF-1R. The company also develops an anti-thyroid-stimulating hormone receptor (TSHR) candidate for the treatment of Graves' disease and TED. Its portfolio of engineered inhibitors of the neonatal Fc receptor (FcFn) includes VRDN-006, a highly selective Fc fragment, and VRDN-008, a half-life extended bispecific FcRn inhibitor comprising an GC fragment and an albumin-binding domain designed to prolong IGG suppression. The company was formerly known as Miragen Therapeutics, Inc. and changed its name to Viridian Therapeutics, Inc. in January 2021. Viridian Therapeutics, Inc. was incorporated in 2010 and is headquartered in Waltham, Massachusetts.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
Viridian Therapeutics is a clinical-stage biopharmaceutical company developing targeted therapies for thyroid eye disease and related ophthalmic and fibrotic disorders. Long-term growth may be driven by clinical trial readouts, regulatory approvals, potential label expansion and strategic collaborations. Investors may find exposure attractive because the company appears positioned to generate meaningful value from positive late-stage data.
Material investment risks include high clinical and regulatory failure risk, competition from established therapies, ongoing negative earnings with potential need for additional financing and execution risk; investors should monitor trial outcomes and cash runway.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -342.60M | -269.95M | -237.73M | -129.87M | -79.41M |
| Net income | -342.60M | -269.95M | -237.73M | -125.44M | -79.42M |
| Selling general administrative | 95.31M | 61.08M | 95.00M | 35.18M | 25.80M |
| Gross profit | 70.85M | 0.30M | 0.31M | 1.77M | 2.96M |
| Reconciled depreciation | 0.46M | 0.54M | 0.47M | 0.26M | 0.12M |
| Ebit | -337.65M | -266.90M | -235.89M | -134.30M | -79.73M |
| Ebitda | -337.19M | -265.66M | -235.37M | -129.39M | -79.29M |
| Depreciation and amortization | 0.46M | 1.24M | 0.52M | 4.92M | 0.44M |
| Non operating income net other | - | - | - | 4.68M | 0.17M |
| Operating income | -363.39M | -299.04M | -254.45M | -134.30M | -79.73M |
| Other operating expenses | 434.24M | 299.34M | 254.76M | 136.08M | 82.69M |
| Interest expense | 4.95M | 3.05M | 1.85M | 0.49M | 0.00M |
| Interest income | 27.40M | 32.13M | 16.48M | 4.92M | 0.32M |
| Net interest income | 22.45M | 29.09M | 15.38M | 4.43M | 0.32M |
| Income tax expense | - | -269.95M | 18.56M | -4.43M | 0.00M |
| Total revenue | 70.85M | 0.30M | 0.31M | 1.77M | 2.96M |
| Total operating expenses | 434.24M | 299.34M | 254.76M | 136.08M | 82.69M |
| Cost of revenue | 1.16M | 1.24M | 1.32M | - | - |
| Total other income expense net | 20.79M | 29.09M | 16.72M | 4.43M | 0.32M |
| Net income from continuing ops | -342.60M | -269.95M | -216.66M | -130.11M | -79.56M |
| Net income applicable to common shares | - | - | - | -129.87M | -79.41M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 899.42M | 742.40M | 490.42M | 435.09M | 203.71M |
| Other current assets | 19.58M | 20.88M | 9.01M | 6.52M | 2.75M |
| Total liab | 177.25M | 70.76M | 48.40M | 40.03M | 15.99M |
| Total stockholder equity | 722.17M | 671.64M | 442.02M | 395.06M | 187.72M |
| Other current liab | 60.89M | 44.93M | 23.27M | 18.21M | 10.50M |
| Common stock | 1.02M | 0.81M | 0.54M | 0.41M | 0.24M |
| Capital stock | 133.07M | 189.69M | 207.06M | 142.56M | 134.07M |
| Retained earnings | -1338.46M | -995.86M | -725.91M | -488.17M | -358.30M |
| Other liab | - | - | - | 0.93M | 2.36M |
| Other assets | - | - | - | 0.98M | 318.13M |
| Cash | 212.38M | 99.59M | 102.83M | 155.58M | 42.30M |
| Total current liabilities | 70.70M | 47.87M | 26.64M | 33.35M | 13.64M |
| Current deferred revenue | 0.37M | 0.29M | 0.29M | 0.29M | 0.29M |
| Net debt | -161.69M | -78.50M | -81.78M | -150.32M | -41.78M |
| Short term debt | 0.75M | 0.51M | 0.84M | 0.61M | 0.52M |
| Short long term debt total | 50.69M | 21.09M | 21.05M | 5.26M | 0.52M |
| Other stockholder equity | 1927.10M | 1477.81M | 960.54M | 741.07M | 412.10M |
| Property plant equipment | - | - | - | 1.33M | 0.38M |
| Total current assets | 894.23M | 738.46M | 486.48M | 424.55M | 200.16M |
| Net tangible assets | - | - | - | 252.92M | 53.88M |
| Short term investments | 662.27M | 617.99M | 374.54M | 268.97M | 154.67M |
| Net receivables | - | - | 0.10M | 0.10M | 0.45M |
| Long term debt | 49.94M | 20.58M | 20.20M | 4.64M | - |
| Inventory | - | - | - | -6.62M | - |
| Accounts payable | 8.68M | 2.14M | 2.24M | 14.23M | 2.33M |
| Accumulated other comprehensive income | 0.45M | -0.01M | 0.34M | -0.39M | -0.16M |
| Common stock total equity | - | - | - | 0.41M | 0.24M |
| Preferred stock total equity | - | - | - | 142.15M | 133.83M |
| Retained earnings total equity | - | - | - | -488.17M | -358.30M |
| Non currrent assets other | 1.54M | 0.50M | 0.60M | 7.61M | 1.49M |
| Non current assets total | 5.18M | 3.94M | 3.95M | 10.54M | 3.55M |
| Capital lease obligations | 0.75M | 0.51M | 0.84M | 0.61M | 0.52M |
| Long term debt total | - | - | - | 4.64M | - |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | -37.07M | -228.65M | -105.14M | -114.33M | -74.03M |
| Change to liabilities | - | - | - | 19.24M | 3.04M |
| Total cashflows from investing activities | -37.56M | -228.65M | -94.25M | -115.13M | -74.29M |
| Net borrowings | 28.88M | 0.00M | 15.00M | 4.55M | 5.00M |
| Total cash from financing activities | 426.74M | 457.74M | 225.67M | 322.24M | 125.28M |
| Change to operating activities | - | - | - | 4.38M | -0.12M |
| Net income | -342.60M | -269.95M | -237.73M | -129.87M | -79.41M |
| Change in cash | 112.79M | -3.23M | -52.75M | 113.28M | -3.60M |
| Begin period cash flow | 99.59M | 102.83M | 155.58M | 42.30M | 45.90M |
| End period cash flow | 212.38M | 99.59M | 102.83M | 155.58M | 42.30M |
| Total cash from operating activities | -276.39M | -232.32M | -184.17M | -93.84M | -54.58M |
| Issuance of capital stock | 352.20M | 478.66M | 25.09M | 335.87M | 131.20M |
| Depreciation | -6.76M | 0.54M | 0.52M | 0.26M | 0.12M |
| Other cashflows from investing activities | - | -228.65M | - | - | 0.08M |
| Dividends paid | - | - | 14.49M | - | - |
| Change to account receivables | - | 0.10M | - | 0.35M | -0.45M |
| Sale purchase of stock | 1.12M | - | 0.58M | 0.18M | 125.28M |
| Other cashflows from financing activities | 49.54M | 4.08M | 85.60M | 30.63M | 11.03M |
| Change to netincome | - | - | - | 19.77M | 22.04M |
| Capital expenditures | 0.49M | 0.51M | 0.90M | 0.80M | 0.34M |
| Cash flows other operating | - | - | - | -3.24M | -1.42M |
| Cash and cash equivalents changes | - | - | - | 113.28M | -3.60M |
| Change in working capital | 23.03M | 9.60M | -9.43M | 15.96M | 1.72M |
| Stock based compensation | 44.30M | 42.15M | 67.17M | 19.77M | 14.46M |
| Other non cash items | 5.63M | -14.66M | -4.71M | 0.05M | 7.49M |
| Free cash flow | -276.89M | -232.83M | -185.07M | -94.64M | -54.92M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| VRDN Viridian Therapeutics Inc |
1.49 5.21% |
29.98 | - | 1.01 | 34.77 | 4.46 | 26.37 | -3.18 |
| NVO Novo Nordisk A/S |
1.09 2.72% |
41.41 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
3.78 0.69% |
550.87 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
15.61 1.73% |
919.96 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Viridian Therapeutics, Inc. engages in discovering, developing, and commercializing treatments for serious and rare diseases. It develops IGF-1R therapies to treat thyroid eye disease (TED), including Veligrotrug, a differentiated humanized monoclonal antibody targeting IGF-1R intravenously administered, and Elegrobart, a low-volume, infrequently dosed subcutaneous IGF-1R. The company also develops an anti-thyroid-stimulating hormone receptor (TSHR) candidate for the treatment of Graves' disease and TED. Its portfolio of engineered inhibitors of the neonatal Fc receptor (FcFn) includes VRDN-006, a highly selective Fc fragment, and VRDN-008, a half-life extended bispecific FcRn inhibitor comprising an GC fragment and an albumin-binding domain designed to prolong IGG suppression. The company was formerly known as Miragen Therapeutics, Inc. and changed its name to Viridian Therapeutics, Inc. in January 2021. Viridian Therapeutics, Inc. was incorporated in 2010 and is headquartered in Waltham, Massachusetts.
221 Crescent Street, Waltham, MA, United States, 02453
617 272 4600
252
| Name | Title | Year Born |
|---|---|---|
| Dr. Jonathan Violin M.B.A., Ph.D. | Co-Founder, CEO, Pres & Director | 1975 |
| Mr. Kristian Humer M.B.A. | CFO, Chief Bus. Officer, Principal Financial Officer & Principal Accounting Officer | 1975 |
| Dr. Barrett Katz CMO, M.B.A., M.D., MBA | Chief Medical Officer | 1950 |
| Dr. Eric N. Olson Ph.D. | Co-Founder & Chairman of Scientific Advisory Board | NA |
| Dr. Michael R. Bristow M.D., Ph.D. | Co-Founder & Member of the Scientific Advisory Board | 1945 |
| Dr. Marvin H. Caruthers Ph.D. | Co-Founder & Scientific Advisory Board Member | 1940 |
| Mr. Vahe Bedian Ph.D. | Co-Founder & Scientific Advisor | NA |
| Ms. Carrie Melvin M.B.A. | Chief Operating Officer | NA |
| Dr. Rob Henderson Ph.D. | Chief Scientific Officer | NA |
| Mr. Todd James IRC | Sr. VP of Corp. Affairs & Investor Relations | NA |
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