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Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on developing product candidates for cancer treatment. The company's lead product candidate is IBTROZI (taletrectinib), a ROS1 inhibitor for the treatment of patients with ROS1+ non-small cell lung cancer. It is also developing Safusidenib, an inhibitor of mutant isocitrate dehydrogenase 1 in phase 3 clinical trials for the maintenance treatment of high-risk or high-grade IDH1-mutant astrocytoma with safusidenib against placebo. The company was founded in 2018 and is headquartered in New York, New York.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
Nuvation Bio Inc is a clinical-stage biopharmaceutical company developing targeted therapies for cancer. Long-term growth may be driven by progress in its clinical pipeline, regulatory approvals and strategic partnerships, and investors may find upside if programs achieve positive trial readouts addressing unmet oncology needs.
Key risks include clinical trial failures and regulatory setbacks, substantial financing requirements that could dilute shareholders, and intense competition in oncology drug development.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -204.63M | -567.94M | -75.80M | -104.20M | -86.85M |
| Net income | -204.63M | -567.94M | -75.80M | -88.66M | -79.73M |
| Selling general administrative | 151.56M | 66.73M | 28.53M | 31.92M | 24.28M |
| Selling and marketing expenses | - | 2.50M | 1.70M | - | 0.64M |
| Gross profit | 54.46M | 0.80M | -0.22M | - | - |
| Reconciled depreciation | 1.74M | 0.68M | 0.22M | 0.20M | 0.18M |
| Ebit | -190.94M | -567.60M | -75.80M | -119.73M | -93.32M |
| Ebitda | -189.21M | -566.91M | -75.58M | -128.69M | -97.28M |
| Depreciation and amortization | 1.74M | 0.68M | 0.22M | -8.96M | -3.97M |
| Non operating income net other | - | - | - | 15.54M | 6.63M |
| Operating income | -213.06M | -592.63M | -99.82M | -119.73M | -93.32M |
| Other operating expenses | 275.97M | 600.50M | 99.82M | 119.73M | 93.32M |
| Interest expense | 13.68M | 0.34M | 0.00M | -9.16M | 0.64M |
| Tax provision | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Interest income | 21.43M | 27.06M | 24.61M | 7.45M | 2.96M |
| Net interest income | 7.75M | 26.72M | 24.61M | 7.45M | 2.96M |
| Income tax expense | - | - | - | -15.54M | -7.11M |
| Total revenue | 62.90M | 7.87M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 267.52M | 593.42M | 99.82M | 119.73M | 93.32M |
| Cost of revenue | 8.44M | 7.08M | 0.22M | - | - |
| Total other income expense net | 8.44M | 24.69M | 24.02M | 15.54M | 6.47M |
| Net income from continuing ops | -204.63M | -567.94M | -75.80M | -104.20M | -86.85M |
| Net income applicable to common shares | - | - | - | -104.20M | -86.85M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 594.82M | 540.63M | 621.48M | 672.14M | 776.15M |
| Intangible assets | 11.21M | 4.62M | - | - | - |
| Other current assets | 11.54M | 7.27M | 1.52M | 3.82M | 3.64M |
| Total liab | 289.11M | 76.84M | 16.36M | 17.07M | 30.15M |
| Total stockholder equity | 305.72M | 463.79M | 605.12M | 655.08M | 746.00M |
| Other current liab | 65.15M | 32.15M | 9.65M | 9.82M | 12.14M |
| Common stock | 1421.27M | 1373.96M | 947.75M | 927.60M | 909.99M |
| Capital stock | 1421.27M | 1373.96M | 947.75M | 927.60M | 909.99M |
| Retained earnings | -1115.37M | -910.74M | -342.80M | -267.00M | -162.80M |
| Other liab | - | - | - | 0.85M | 11.04M |
| Other assets | - | - | 0.00M | 0.14M | 0.42M |
| Cash | 164.09M | 35.72M | 42.65M | 101.10M | 132.42M |
| Total current liabilities | 82.23M | 58.24M | 13.97M | 13.16M | 16.93M |
| Current deferred revenue | - | 11.12M | - | - | - |
| Net debt | -153.94M | -26.81M | -38.64M | -96.84M | -129.37M |
| Short term debt | 7.60M | 7.95M | 1.97M | 1.21M | 0.86M |
| Short long term debt | 5.72M | 6.28M | - | - | - |
| Short long term debt total | 10.15M | 8.91M | 4.01M | 4.26M | 3.06M |
| Other stockholder equity | - | - | - | -5.53M | -745.25M |
| Property plant equipment | - | - | - | 0.89M | 3.66M |
| Total current assets | 571.52M | 526.25M | 616.43M | 667.32M | 772.07M |
| Net tangible assets | - | - | - | 655.08M | 746.00M |
| Short term investments | 365.12M | 466.97M | 568.56M | 559.91M | 632.97M |
| Net receivables | 19.36M | 16.29M | 3.70M | 2.48M | 3.04M |
| Long term debt | 47.21M | - | - | - | - |
| Inventory | 11.41M | 0.00M | - | - | 643.08M |
| Accounts payable | 9.48M | 6.35M | 2.21M | 2.14M | 3.92M |
| Accumulated other comprehensive income | -0.19M | 0.57M | 0.18M | -5.53M | -1.19M |
| Common stock total equity | - | - | - | 927.60M | 909.99M |
| Retained earnings total equity | - | - | - | -267.00M | -162.80M |
| Non currrent assets other | 7.61M | 6.76M | 0.73M | 559.49M | 0.42M |
| Non current assets total | 23.30M | 14.37M | 5.05M | 4.82M | 4.08M |
| Capital lease obligations | 4.42M | 2.63M | 4.01M | 4.26M | 3.06M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | 107.87M | 122.70M | 8.92M | 63.81M | -454.39M |
| Change to liabilities | - | - | - | -4.11M | 1.86M |
| Total cashflows from investing activities | 99.52M | 122.70M | 8.92M | 63.46M | -454.67M |
| Net borrowings | 48.20M | -4.55M | 0.00M | - | - |
| Total cash from financing activities | 202.53M | 0.33M | 0.63M | 1.33M | 625.53M |
| Change to operating activities | - | - | - | -1.66M | 2.93M |
| Net income | -204.63M | -567.94M | -75.80M | -104.20M | -86.85M |
| Change in cash | 128.36M | -6.93M | -58.45M | -31.32M | 102.67M |
| Begin period cash flow | 35.72M | 42.65M | 101.10M | 132.42M | 29.75M |
| End period cash flow | 164.09M | 35.72M | 42.65M | 101.10M | 132.42M |
| Total cash from operating activities | -173.43M | -130.41M | -68.00M | -96.11M | -68.19M |
| Issuance of capital stock | - | - | - | - | 0.00M |
| Depreciation | 1.74M | 0.68M | 0.22M | 0.20M | 0.18M |
| Other cashflows from investing activities | 99.52M | 110.44M | 0.01M | 0.01M | - |
| Change to inventory | -11.41M | 0.00M | - | - | - |
| Change to account receivables | -3.07M | -12.59M | -1.22M | - | - |
| Sale purchase of stock | - | - | - | 0.94M | 0.76M |
| Other cashflows from financing activities | 202.53M | 4.88M | 0.63M | 1.33M | 625.53M |
| Change to netincome | - | - | - | 7.38M | 13.68M |
| Capital expenditures | 0.35M | 0.16M | 0.07M | 0.37M | 0.28M |
| Change receivables | - | - | - | 0.55M | -1.95M |
| Cash flows other operating | - | - | - | 0.39M | -10.77M |
| Cash and cash equivalents changes | - | - | - | -31.32M | 102.67M |
| Change in working capital | -11.98M | -12.51M | 0.54M | -3.45M | 4.79M |
| Stock based compensation | 35.89M | 32.27M | 19.51M | 16.29M | 9.27M |
| Other non cash items | 5.55M | 417.07M | -12.47M | -4.95M | 3.97M |
| Free cash flow | -173.78M | -130.57M | -68.07M | -96.48M | -68.47M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| NUVB Nuvation Bio Inc |
0.12 2.88% |
4.28 | - | - | 11.99 | 8.22 | 9.87 | 2.23 |
| NVO Novo Nordisk A/S |
1.03 2.56% |
41.34 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
1.49 0.27% |
548.58 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
18.16 2.01% |
922.51 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on developing product candidates for cancer treatment. The company's lead product candidate is IBTROZI (taletrectinib), a ROS1 inhibitor for the treatment of patients with ROS1+ non-small cell lung cancer. It is also developing Safusidenib, an inhibitor of mutant isocitrate dehydrogenase 1 in phase 3 clinical trials for the maintenance treatment of high-risk or high-grade IDH1-mutant astrocytoma with safusidenib against placebo. The company was founded in 2018 and is headquartered in New York, New York.
| Name | Title | Year Born |
|---|---|---|
| Dr. David T. Hung M.D. | Founder, Pres, CEO & Director | 1958 |
| Ms. Jennifer A. Fox | CFO & Sec. | 1972 |
| Dr. David C. Hanley Ph.D. | Chief Technical Operations Officer | 1970 |
| Dr. Gary Hattersley Ph.D. | Chief Scientific Officer | 1967 |
| Ms. Stacy Markel | Chief People Officer | 1965 |
| Ms. Kerry A. Wentworth | Chief Regulatory Officer | 1973 |
| Dr. David Liu M.D., Ph.D. | Chief Medical Officer | NA |
| Dr. David T. Hung M.D. | Founder, President, CEO & Chairman | 1958 |
| Mr. Philippe Pierre Sauvage | CFO & Principal Financial Officer | 1978 |
| Mr. Moses Makunje CPA | VP of Finance and Principal Accounting & Financial Officer | 1979 |
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