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Rakovina Therapeutics Inc. (TSX-V: RKV | FSE: 7JO0) is a biopharmaceutical company developing oncology drug candidates using proprietary AI-driven discovery platforms. The company holds exclusive licenses to Deep Docking™ and Enki™, two computational tools designed to rapidly analyze large-scale chemical libraries to identify promising compounds for further development. Rakovina integrates this computational approach with laboratory-based validation through its research collaboration with the University of British Columbia.
During the first half of 2025, Rakovina made progress across multiple research and corporate development fronts. At the American Association of Cancer Research (AACR) annual meeting, the company presented two scientific posters outlining data from its DNA damage response (DDR) inhibitor programs.
The kt-2000 series, focused on PARP1 inhibitors, showed improved metabolic stability in early testing. In vitro results demonstrated low clearance rates and extended half-life compared to peer compounds. Animal studies reported plasma exposure data consistent with central nervous system (CNS) penetration, which is being further evaluated as part of the program’s preclinical assessment.
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