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Mesoblast Limited, together with its subsidiaries, engages in the development of regenerative medicine products in Australia. The company's proprietary regenerative medicine technology platform is based on specialized cells known as mesenchymal lineage cells. It offers Ryoncil for the treatment of systemic inflammatory diseases, including steroid refractory acute graft versus host disease, Duchenne muscular dystrophy, and biologic refractory inflammatory bowel disease, as well as ulcerative colitis and Crohn's disease; Remestemcel-L, which is in Phase III clinical trials to treat chronic heart failure and chronic low back pain due to degenerative disc disease; and Revascor for the treatment of hypoplastic left heart syndrome. The company is also developing MPC-300-IV to treat biologic refractory rheumatoid arthritis diabetic nephropathy; MPC-150-IM for the treatment or prevention of chronic heart failure; Ryoncil for the treatment of pediatric SR-aGVHD; and MPC-25-IC for the treatment or prevention of acute myocardial infarction. It has strategic partnerships with Tasly Pharmaceutical Group to offer MPC-150-IM; Grünenthal GmbH to develop and commercialize MPC-06-ID for the treatment of chronic low back pain due to degenerative disc disease in patients; and JCR Pharmaceuticals Co. Ltd. to treat wound healing in patients with epidermolysis bullosa and for the treatment of neonatal hypoxic ischemic encephalopathy. Mesoblast Limited was incorporated in 2004 and is headquartered in Melbourne, Australia.
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Mesoblast develops allogeneic cellular medicines derived from mesenchymal lineage cells for inflammatory, cardiovascular and orthopedic conditions, advancing multiple clinical-stage candidates and manufacturing capabilities. Long-term growth drivers include potential regulatory approvals across indications, partnering and licensing revenue, and scalable cell-manufacturing that could support commercial roll-out. The company's appeal to investors derives from exposure to novel biologic therapies that may benefit from successful trials and commercialization.
Principal risks include significant regulatory and clinical trial uncertainty, potential need for additional financing to reach commercialization, and competitive pressures in cell therapy and biologics.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2026-06-30 | 2025-06-30 | 2024-06-30 | 2023-06-30 | 2022-06-30 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2026-06-30 | 2025-06-30 | 2024-06-30 | 2023-06-30 | 2022-06-30 |
| Income before tax | -56.89M | -101.81M | -88.15M | -82.10M | -91.59M |
| Net income | -57.50M | -102.14M | -87.96M | -81.89M | -91.35M |
| Selling general administrative | 57.35M | 23.21M | 23.63M | 25.37M | 27.21M |
| Selling and marketing expenses | - | 16.10M | 15.72M | 27.73M | 30.76M |
| Gross profit | 103.58M | 12.07M | -35.17M | -47.42M | -53.36M |
| Reconciled depreciation | - | 6.40M | 4.67M | 4.11M | 4.38M |
| Ebit | - | -80.06M | -57.97M | -69.14M | -80.95M |
| Ebitda | - | -73.66M | -56.08M | -65.03M | -76.57M |
| Depreciation and amortization | - | 6.40M | 1.90M | 4.11M | 4.38M |
| Operating income | -51.25M | -62.44M | -84.15M | -69.29M | -80.57M |
| Other operating expenses | - | 79.64M | 90.05M | 76.79M | 90.78M |
| Interest expense | 19.87M | 21.75M | 20.66M | 19.44M | 16.91M |
| Tax provision | 0.61M | 0.33M | -0.19M | -0.21M | -0.24M |
| Interest income | 3.91M | 3.55M | 1.82M | 18.78M | 0.00M |
| Net interest income | -17.96M | -19.00M | -18.83M | -19.29M | -17.29M |
| Income tax expense | - | 0.33M | -0.19M | -0.21M | -0.24M |
| Total revenue | 120.25M | 17.20M | 5.90M | 7.50M | 10.21M |
| Total operating expenses | 171.50M | 74.51M | 48.98M | 76.79M | 90.78M |
| Cost of revenue | 16.67M | 5.13M | 41.07M | 54.92M | 63.57M |
| Total other income expense net | 12.32M | -39.37M | -4.00M | 6.48M | 6.27M |
| Net income from continuing ops | -57.50M | -102.14M | -87.96M | -81.89M | -91.35M |
| Net income applicable to common shares | - | -102.14M | -87.96M | -81.89M | -91.35M |
| Breakdown | 2026-06-30 | 2025-06-30 | 2024-06-30 | 2023-06-30 | 2022-06-30 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2026-06-30 | 2025-06-30 | 2024-06-30 | 2023-06-30 | 2022-06-30 |
| Total assets | 773.08M | 784.68M | 669.15M | 669.41M | 662.14M |
| Intangible assets | 431.92M | 437.37M | 441.28M | 442.73M | 444.20M |
| Other current assets | - | - | - | 0.40M | 5.40M |
| Total liab | 204.67M | 187.24M | 188.80M | 167.58M | 165.10M |
| Total stockholder equity | 568.40M | 597.44M | 480.36M | 501.84M | 497.04M |
| Other current liab | 8.91M | 16.73M | 4.65M | 5.43M | 2.19M |
| Common stock | - | - | 1310.81M | 1249.12M | 1165.31M |
| Capital stock | 1530.77M | 1508.85M | 1310.81M | 1249.12M | 1165.31M |
| Retained earnings | -1068.40M | -1010.90M | -908.76M | -820.80M | -738.92M |
| Other liab | - | - | - | 19.11M | 15.02M |
| Good will | 134.45M | 134.45M | 134.45M | 134.45M | 134.45M |
| Other assets | - | - | - | 2.33M | 1.93M |
| Cash | 47.39M | 161.16M | 62.56M | 70.92M | 60.03M |
| Cash and equivalents | - | - | - | -0.00M | 0.01M |
| Total current liabilities | 81.11M | 102.63M | 73.24M | 41.98M | 51.37M |
| Current deferred revenue | - | - | 45.04M | 6.40M | 17.91M |
| Net debt | 71.84M | - | 56.36M | 45.58M | 46.87M |
| Short term debt | - | - | 16.49M | 10.01M | 8.20M |
| Short long term debt | 10.60M | 54.16M | 13.86M | 5.95M | 5.02M |
| Short long term debt total | - | - | 118.92M | 116.50M | 106.91M |
| Other stockholder equity | - | - | - | -428.32M | -426.39M |
| Property plant equipment | - | - | - | 6.49M | 9.96M |
| Total current assets | 197.49M | 204.35M | 86.46M | 81.66M | 69.84M |
| Long term investments | 0.00M | 1.39M | 1.01M | 1.76M | 1.76M |
| Net tangible assets | - | - | - | -75.34M | -81.61M |
| Net receivables | 57.08M | 13.91M | 20.95M | 7.00M | 4.40M |
| Long term debt | 108.64M | 67.74M | 100.48M | 102.81M | 91.62M |
| Inventory | 28.11M | 22.25M | - | - | - |
| Accounts payable | 34.51M | 19.08M | 7.07M | 20.14M | 23.08M |
| Accumulated other comprehensive income | - | - | 78.30M | 73.52M | 70.65M |
| Non currrent assets other | 0.38M | 0.47M | 0.48M | 0.48M | 1.68M |
| Non current assets total | 575.59M | 580.33M | 582.69M | 587.76M | 592.30M |
| Capital lease obligations | 8.10M | 6.26M | 4.58M | 7.73M | 10.27M |
| Long term debt total | - | - | - | 106.48M | 98.70M |
| Breakdown | 2026-06-30 | 2025-06-30 | 2024-06-30 | 2023-06-30 | 2022-06-30 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2026-06-30 | 2025-06-30 | 2024-06-30 | 2023-06-30 | 2022-06-30 |
| Investments | -0.12M | 0.12M | -0.10M | -0.19M | -0.23M |
| Change to liabilities | - | - | - | -0.40M | 4.78M |
| Total cashflows from investing activities | - | 0.12M | -0.10M | -0.19M | -0.23M |
| Net borrowings | -5.94M | -9.77M | -13.52M | -2.66M | -6.33M |
| Total cash from financing activities | -15.33M | 147.34M | 40.25M | 74.50M | -9.87M |
| Change to operating activities | - | - | - | 0.43M | -0.05M |
| Net income | -57.50M | -102.14M | -87.96M | -81.89M | -91.35M |
| Change in cash | -60.18M | 98.59M | -8.36M | 10.87M | -76.43M |
| Begin period cash flow | 161.55M | 62.96M | 71.32M | 60.45M | 136.88M |
| End period cash flow | 102.91M | 161.55M | 62.96M | 71.32M | 60.45M |
| Total cash from operating activities | - | -49.95M | -48.46M | -63.27M | -65.78M |
| Issuance of capital stock | 2.60M | 161.21M | 65.41M | 88.64M | 0.21M |
| Depreciation | - | 6.40M | 4.67M | 4.11M | 4.38M |
| Other cashflows from investing activities | - | 0.56M | -0.06M | 0.07M | -0.07M |
| Dividends paid | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Change to inventory | - | 0.83M | 0.00M | - | - |
| Change to account receivables | - | 6.29M | -15.47M | -0.12M | 0.14M |
| Sale purchase of stock | - | 168.03M | 65.41M | 88.64M | 8.29M |
| Other cashflows from financing activities | - | -4.10M | -11.63M | -11.48M | 48.17M |
| Change to netincome | - | - | - | 16.98M | 16.32M |
| Capital expenditures | 0.90M | 0.73M | 0.33M | 0.31M | 0.23M |
| Change in working capital | - | -3.04M | -2.63M | -2.47M | 4.87M |
| Stock based compensation | - | 22.09M | 5.87M | 3.65M | 5.54M |
| Other non cash items | - | 26.41M | 31.78M | 13.54M | 11.02M |
| Free cash flow | -44.73M | -50.68M | -48.79M | -63.58M | -66.01M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(AUD) |
Price
(AUD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| MSB Mesoblast Ltd |
-0.14 6.45% |
2.03 | - | 454.55 | 23.43 | 3.36 | 18.28 | -9.86 |
| CSL CSL Ltd |
-0.36 0.18% |
202.04 | - | 22.57 | 6.15 | 4.48 | 4.82 | 10.06 |
| TLX TELIX Pharmaceuticals Ltd |
-0.41 2.91% |
13.67 | 93.87 | 166.67 | 5.37 | 6.37 | 3.85 | 47.29 |
| NEU Neuren Pharmaceuticals Ltd |
- -% |
23.24 | 154.93 | 36.36 | 42.38 | 7.52 | 31.95 | 160.40 |
| PYC PYC Therapeutics Ltd |
-0.05 2.59% |
1.88 | - | 12.00 | 73.11 | 2.63 | 25.02 | -8.41 |
Mesoblast Limited, together with its subsidiaries, engages in the development of regenerative medicine products in Australia. The company's proprietary regenerative medicine technology platform is based on specialized cells known as mesenchymal lineage cells. It offers Ryoncil for the treatment of systemic inflammatory diseases, including steroid refractory acute graft versus host disease, Duchenne muscular dystrophy, and biologic refractory inflammatory bowel disease, as well as ulcerative colitis and Crohn's disease; Remestemcel-L, which is in Phase III clinical trials to treat chronic heart failure and chronic low back pain due to degenerative disc disease; and Revascor for the treatment of hypoplastic left heart syndrome. The company is also developing MPC-300-IV to treat biologic refractory rheumatoid arthritis diabetic nephropathy; MPC-150-IM for the treatment or prevention of chronic heart failure; Ryoncil for the treatment of pediatric SR-aGVHD; and MPC-25-IC for the treatment or prevention of acute myocardial infarction. It has strategic partnerships with Tasly Pharmaceutical Group to offer MPC-150-IM; Grünenthal GmbH to develop and commercialize MPC-06-ID for the treatment of chronic low back pain due to degenerative disc disease in patients; and JCR Pharmaceuticals Co. Ltd. to treat wound healing in patients with epidermolysis bullosa and for the treatment of neonatal hypoxic ischemic encephalopathy. Mesoblast Limited was incorporated in 2004 and is headquartered in Melbourne, Australia.
| Name | Title | Year Born |
|---|---|---|
| Dr. Silviu Itescu FACP, FACRA, FRACP, MBBS (Hons) | Founder, CEO, MD, Chairman of Scientific Advisory Board & Exec. Director | 1957 |
| Dr. Eric A. Rose M.D. | Chief Medical Officer & Exec. Director | 1951 |
| Mr. Andrew Chaponnel B.Com. | Interim Chief Fin. Officer | NA |
| Ms. Dagmar Rosa-Bjorkeson M.B.A., M.S. | Chief Operating Officer | 1964 |
| Mr. Peter T. Howard B.Sc., L.L.B., BSc, LLB (Hons) | Gen. Counsel & Corp. Exec. | 1968 |
| Mr. Roger D. Brown BA | Head of Spinal Orthopedic Disorders | NA |
| Mr. Michael Schuster M.B.A., MS, BSc, MBA | Head of Pharma Partnering | 1977 |
| Ms. Geraldine Storton B.Sc., M.B.A., Bsc, MMS, MBA | Head of Regulatory Affairs & Quality Management | NA |
| Mr. Justin Horst B.S. | Head of Manufacturing | NA |
| Ms. Niva Sivakumar B.Com., L.L.B. | Joint Company Sec. | NA |
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