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Neuren Pharmaceuticals Limited, a biopharmaceutical company, develops drugs for the treatment of neurological disorders. It develops and commercializes DAYBUE (trofinetide) for the treatment of Rett syndrome in adults and pediatric patients 2 years of age and older, as well as in Phase 2 clinical trial to treat Fragile X syndrome. The company also develops NNZ-2591, which has completed Phase 2 clinical trial for the treatment of Phelan-McDermid; and in Phase 2 clinical trial for the treatment of Angelman and Pitt Hopkins. In addition, it develops NNZ-2591, which is in preclinical trial stage for the treatment of Prader-Willi syndrome, Hypoxic Ischemic Encephalopathy, and SYNGAP1. The company was incorporated in 2001 and is based in Hawthorn East, Australia.
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Neuren Pharmaceuticals (ASX: NEU) is a clinical-stage biotech developing peptide therapies for neurodevelopmental disorders, notably NNZ-2566 (trofinetide) licensed to a commercial partner and NNZ-2591 advancing in clinical development. Long-term growth may be supported by royalty and milestone revenue from trofinetide, potential partnering or label expansion for NNZ-2591, and adoption in rare pediatric neurology.
Principal risks are concentration on a single royalty-bearing product and reliance on a partner for commercialization, clinical and regulatory uncertainty for NNZ-2591, limited internal resources and the potential need for additional funding, and challenges with market access.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | 38.93M | 182.94M | 205.14M | 0.18M | -7.79M |
| Net income | 30.44M | 142.04M | 157.08M | 2.37M | -7.75M |
| Selling general administrative | - | 4.70M | 5.95M | 3.44M | 1.91M |
| Selling and marketing expenses | - | - | 0.02M | - | - |
| Gross profit | 64.61M | 213.22M | 205.17M | 14.55M | - |
| Reconciled depreciation | - | 0.02M | 0.02M | 0.01M | 0.01M |
| Ebit | 22.02M | 175.55M | 199.25M | -1.61M | -11.44M |
| Ebitda | 22.05M | 175.57M | 199.26M | -1.60M | -11.43M |
| Depreciation and amortization | 0.02M | 0.02M | 0.02M | 0.01M | 0.01M |
| Operating income | 22.02M | 175.55M | 172.49M | -1.61M | -11.44M |
| Other operating expenses | 42.61M | 37.69M | 59.45M | 16.16M | 11.44M |
| Interest expense | - | - | - | 0.39M | 3.64M |
| Tax provision | - | 40.90M | 48.06M | 0.00M | 0.00M |
| Interest income | - | 11.01M | 5.69M | 0.39M | 0.40M |
| Net interest income | - | 11.01M | 5.69M | 0.39M | 0.04M |
| Income tax expense | 8.49M | 40.90M | 48.06M | -2.18M | -0.05M |
| Total revenue | 64.63M | 213.24M | 231.93M | 14.55M | 0.04M |
| Total operating expenses | 42.59M | 37.67M | 32.70M | 16.16M | 11.44M |
| Cost of revenue | 0.02M | 0.02M | 26.75M | - | - |
| Total other income expense net | 16.91M | 7.39M | 32.65M | 1.79M | 3.64M |
| Net income from continuing ops | - | 142.04M | 157.08M | 0.18M | -7.79M |
| Net income applicable to common shares | - | 142.04M | 157.08M | 0.18M | -7.79M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 342.86M | 409.71M | 247.97M | 43.27M | 40.06M |
| Other current assets | 9.57M | 4.17M | 4.21M | 1.98M | 1.84M |
| Total liab | 4.41M | 45.80M | 42.76M | 1.68M | 0.80M |
| Total stockholder equity | 338.45M | 363.90M | 205.21M | 41.59M | 39.25M |
| Other current liab | 3.46M | 44.31M | 42.09M | 1.42M | 0.56M |
| Common stock | 134.94M | 165.27M | 173.13M | 167.74M | 167.58M |
| Capital stock | - | - | 173.13M | 167.74M | 167.58M |
| Retained earnings | 210.87M | 180.43M | 38.39M | -118.69M | -118.88M |
| Other assets | - | - | 0.00M | - | - |
| Cash | 4.23M | 3.15M | 17.09M | 40.18M | 36.78M |
| Cash and equivalents | - | - | - | 37.88M | 29.87M |
| Total current liabilities | 4.34M | 45.76M | 42.76M | 1.68M | 0.80M |
| Net debt | -4.23M | -3.15M | -17.09M | -40.18M | -36.78M |
| Short term debt | - | - | - | 0.00M | 0.00M |
| Other stockholder equity | - | 0.00M | - | -10.68M | -9.45M |
| Property plant equipment | - | - | - | 0.02M | 0.01M |
| Total current assets | 332.23M | 399.33M | 247.16M | 43.25M | 40.04M |
| Net tangible assets | - | - | - | 41.59M | 39.25M |
| Short term investments | 291.89M | 219.09M | 211.44M | - | - |
| Net receivables | 26.54M | 172.91M | 14.41M | 1.09M | 1.42M |
| Accounts payable | 0.88M | 1.45M | 0.68M | 0.26M | 0.24M |
| Accumulated other comprehensive income | -7.36M | 18.20M | -6.31M | -7.46M | -9.45M |
| Non currrent assets other | - | 10.35M | -0.00M | - | - |
| Non current assets total | 10.63M | 10.38M | 0.81M | 0.02M | 0.01M |
| Long term debt total | - | - | - | 0.00M | 0.00M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | - | 4.13M | -211.49M | -0.02M | -0.01M |
| Change to liabilities | - | - | - | 0.34M | -0.11M |
| Total cashflows from investing activities | -88.01M | 4.13M | -211.49M | -0.02M | -0.01M |
| Total cash from financing activities | -33.22M | -8.78M | 3.62M | -0.00M | 22.18M |
| Net income | 30.44M | 142.04M | 157.08M | 2.37M | -7.79M |
| Change in cash | 1.07M | -13.94M | -23.09M | 3.40M | 12.60M |
| Begin period cash flow | 3.15M | 17.09M | 40.18M | 36.78M | 24.19M |
| End period cash flow | 4.23M | 3.15M | 17.09M | 40.18M | 36.78M |
| Total cash from operating activities | 125.42M | -11.27M | 184.93M | 2.38M | -9.97M |
| Issuance of capital stock | - | 1.66M | 3.64M | - | 23.28M |
| Depreciation | 0.02M | 0.02M | 0.02M | 0.01M | 0.01M |
| Other cashflows from investing activities | - | 4.14M | -211.44M | - | - |
| Change to account receivables | 154.59M | -157.11M | -15.55M | 0.19M | -2.51M |
| Sale purchase of stock | -39.57M | -10.43M | -0.02M | -0.00M | -1.11M |
| Other cashflows from financing activities | - | 1.65M | -211.49M | -0.02M | -0.01M |
| Change to netincome | - | - | - | 2.87M | 0.44M |
| Capital expenditures | 0.04M | 0.01M | 0.04M | 0.02M | 0.01M |
| Change in working capital | 96.02M | -157.59M | 23.24M | -1.23M | 0.82M |
| Stock based compensation | - | 1.23M | 2.93M | - | - |
| Other non cash items | -1.06M | 4.27M | 7.52M | -2.38M | 7.79M |
| Free cash flow | 125.39M | -11.28M | 184.88M | 2.36M | -9.98M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(AUD) |
Price
(AUD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| NEU Neuren Pharmaceuticals Ltd |
- -% |
23.24 | 154.93 | 36.36 | 42.38 | 7.52 | 31.95 | 160.40 |
| CSL CSL Ltd |
-0.36 0.18% |
202.04 | - | 22.57 | 6.15 | 4.48 | 4.82 | 10.06 |
| TLX TELIX Pharmaceuticals Ltd |
-0.41 2.91% |
13.67 | 93.87 | 166.67 | 5.37 | 6.37 | 3.85 | 47.29 |
| MSB Mesoblast Ltd |
-0.14 6.45% |
2.03 | - | 454.55 | 23.43 | 3.36 | 18.28 | -9.86 |
| PYC PYC Therapeutics Ltd |
-0.05 2.59% |
1.88 | - | 12.00 | 73.11 | 2.63 | 25.02 | -8.41 |
Neuren Pharmaceuticals Limited, a biopharmaceutical company, develops drugs for the treatment of neurological disorders. It develops and commercializes DAYBUE (trofinetide) for the treatment of Rett syndrome in adults and pediatric patients 2 years of age and older, as well as in Phase 2 clinical trial to treat Fragile X syndrome. The company also develops NNZ-2591, which has completed Phase 2 clinical trial for the treatment of Phelan-McDermid; and in Phase 2 clinical trial for the treatment of Angelman and Pitt Hopkins. In addition, it develops NNZ-2591, which is in preclinical trial stage for the treatment of Prader-Willi syndrome, Hypoxic Ischemic Encephalopathy, and SYNGAP1. The company was incorporated in 2001 and is based in Hawthorn East, Australia.
117 Camberwell Road, Hawthorn East, VIC, Australia, 3123
61 3 9092 0480
| Name | Title | Year Born |
|---|---|---|
| Mr. Jonathan Charles Pilcher A.C.A., ACA, B.Sc., BSc (Hons) | CEO, MD & Director | NA |
| Ms. Lauren Frazer C.A. | CFO & Company Sec. | NA |
| Mr. Lawrence Glass | Chief Science Officer | NA |
| Mr. Gerry Zhao | VP of Corp. Devel. | NA |
| Dr. Liza A. Squires M.D. | Chief Medical Officer | NA |
| Mr. Jonathan Charles Pilcher A.C.A., ACA, B.Sc., BSc (Hons), F.C.A. | CEO, MD & Executive Director | NA |
| Ms. Lauren Frazer C.A. | CFO & Company Secretary | NA |
| Mr. Lawrence Glass BA (Biology) | Chief Science Officer | NA |
| Mr. Gerry Zhao | Vice President of Corporate Development | NA |
| Mr. Jonathan Charles Pilcher A.C.A., ACA, B.Sc., BSc (Hons), F.C.A. | CEO, MD & Executive Director | NA |
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