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Aura Biosciences, Inc., a clinical-stage biotechnology company, develops precision therapies to treat solid tumors. The company's proprietary platform enables the targeting of a range of solid tumors using virus-like particles conjugated with drugs or loaded with nucleic acids to create virus-like drug conjugates. Its lead candidate is bel-sar, which is in late-stage clinical development for the treatment of patients with primary choroidal melanoma and other ocular oncology indications, as well as in early-stage clinical development in bladder cancer. It focuses on assessing the safety and efficacy of bel-sar in treating a range of other solid tumors, including bladder cancer. The company was incorporated in 2009 and is headquartered in Boston, Massachusetts.
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Aura Biosciences is a clinical-stage biotechnology company developing tumor-targeted, near-infrared–activated cytolytic agents built on a proprietary virus-like particle platform, with its lead program focused on uveal (ocular) melanoma. Major long-term growth drivers include clinical trial progress toward regulatory approvals, platform extension into additional oncology indications, and strategic collaborations to commercialize novel therapies; investors may find the company attractive because its differentiated activation mechanism may provide targeted tumor cell killing with reduced systemic exposure if clinical data are positive.
The principal investment risks are clinical and regulatory failure combined with substantial cash burn and the likely need for additional financing to continue development.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -106.08M | -86.81M | -76.27M | -58.76M | -35.25M |
| Net income | -106.19M | -86.92M | -76.41M | -57.23M | -34.42M |
| Selling general administrative | 22.49M | 22.81M | 19.76M | 18.06M | 10.09M |
| Selling and marketing expenses | - | - | 19.74M | - | - |
| Gross profit | - | -1.22M | -1.29M | -60.30M | -35.25M |
| Reconciled depreciation | 1.13M | 1.22M | 1.29M | 1.18M | 0.83M |
| Ebit | -112.79M | -96.12M | -84.99M | -60.30M | -35.25M |
| Ebitda | -111.66M | -94.89M | -83.70M | -59.97M | -35.24M |
| Depreciation and amortization | 1.13M | 1.22M | 1.29M | 0.33M | 0.01M |
| Non operating income net other | - | - | - | 1.53M | -0.00M |
| Operating income | -112.79M | -96.12M | -84.99M | -60.30M | -35.25M |
| Other operating expenses | 112.79M | 96.12M | 84.99M | 60.30M | 35.25M |
| Interest expense | - | - | - | 0.85M | 0.01M |
| Tax provision | 0.11M | 0.11M | 0.14M | - | - |
| Interest income | 6.63M | 9.43M | 7.04M | 1.86M | - |
| Net interest income | 6.63M | 9.43M | 7.04M | 1.86M | 0.01M |
| Income tax expense | 0.11M | 0.11M | 0.14M | -1.53M | -0.83M |
| Total revenue | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 112.79M | 96.12M | 83.70M | 60.30M | 35.25M |
| Cost of revenue | - | 1.22M | 1.29M | 60.30M | 35.25M |
| Total other income expense net | 6.71M | 9.31M | 8.72M | 1.53M | -0.00M |
| Net income from continuing ops | -106.19M | -86.92M | -70.84M | -58.76M | -35.25M |
| Net income applicable to common shares | - | - | - | -58.76M | -35.25M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 169.43M | 182.50M | 255.07M | 223.94M | 160.03M |
| Other current assets | 5.50M | 9.53M | 5.62M | 7.87M | 4.62M |
| Total liab | 32.52M | 30.53M | 29.23M | 28.35M | 7.71M |
| Total stockholder equity | 136.91M | 151.97M | 225.85M | 195.58M | 152.31M |
| Other current liab | 13.59M | 9.46M | 7.88M | 4.57M | 0.42M |
| Capital stock | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Retained earnings | -480.42M | -374.23M | -287.31M | -210.90M | -152.14M |
| Other liab | - | - | - | - | 0.08M |
| Other assets | - | - | 0.00M | 1.19M | 0.12M |
| Cash | 59.52M | 31.69M | 41.08M | 121.58M | 149.06M |
| Total current liabilities | 18.38M | 14.91M | 12.36M | 10.46M | 7.27M |
| Current deferred revenue | - | - | - | - | 3.83M |
| Net debt | -42.14M | -12.92M | -21.52M | -100.72M | -148.09M |
| Short term debt | 3.24M | 3.15M | 2.69M | 2.96M | 0.61M |
| Short long term debt total | 17.38M | 18.77M | 19.56M | 20.86M | 0.97M |
| Other stockholder equity | 617.43M | 525.93M | 512.62M | 406.56M | 144.42M |
| Property plant equipment | - | - | - | 5.37M | 5.25M |
| Total current assets | 149.74M | 160.62M | 231.79M | 196.70M | 153.70M |
| Net tangible assets | - | - | - | 195.58M | 152.31M |
| Short term investments | 84.73M | 119.40M | 185.09M | 67.23M | - |
| Accounts payable | 1.55M | 2.30M | 1.79M | 2.92M | 2.40M |
| Accumulated other comprehensive income | -0.10M | 0.26M | 0.54M | -0.07M | - |
| Retained earnings total equity | - | - | - | -210.90M | -152.14M |
| Non currrent assets other | 1.24M | 1.29M | 0.51M | 1.19M | 0.12M |
| Non current assets total | 19.69M | 21.88M | 23.28M | 27.23M | 6.33M |
| Capital lease obligations | 17.38M | 18.77M | 19.56M | 20.86M | 0.97M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | 36.04M | 68.82M | -40.72M | -66.78M | -2.12M |
| Change to liabilities | - | - | - | 0.57M | 3.26M |
| Total cashflows from investing activities | 35.59M | 68.82M | -113.96M | -67.87M | -2.12M |
| Total cash from financing activities | 77.16M | 1.59M | 97.29M | 95.63M | 166.26M |
| Change to operating activities | - | - | - | -3.44M | -1.37M |
| Net income | -106.19M | -86.92M | -76.41M | -58.76M | -35.25M |
| Change in cash | 27.82M | -9.39M | -80.52M | -26.84M | 131.72M |
| Begin period cash flow | 32.46M | 41.85M | 122.37M | 149.21M | 17.49M |
| End period cash flow | 60.28M | 32.46M | 41.85M | 122.37M | 149.21M |
| Total cash from operating activities | -84.74M | -79.81M | -63.85M | -54.60M | -32.41M |
| Issuance of capital stock | 52.57M | 0.00M | 98.37M | 95.20M | 165.93M |
| Depreciation | 1.13M | 1.22M | 1.29M | 1.18M | 0.83M |
| Other cashflows from investing activities | - | -0.00M | - | - | - |
| Sale purchase of stock | - | - | - | 87.08M | 166.27M |
| Other cashflows from financing activities | 77.16M | 1.59M | 94.12M | 87.08M | 87.56M |
| Change to netincome | - | - | - | 6.09M | 2.32M |
| Capital expenditures | 0.45M | 1.25M | 0.71M | 1.09M | 2.12M |
| Cash flows other operating | - | - | - | -3.68M | -3.57M |
| Cash and cash equivalents changes | - | - | - | -26.84M | 131.72M |
| Change in working capital | 5.97M | -2.64M | 4.44M | -3.10M | -0.32M |
| Stock based compensation | 14.32M | 11.72M | 8.77M | 6.41M | 2.31M |
| Other non cash items | 0.03M | -3.19M | -1.95M | -0.33M | 0.00M |
| Free cash flow | -85.19M | -81.06M | -64.56M | -55.70M | -34.53M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|
| AURA Aura Biosciences Inc |
- -% |
7.61 | - | - | - | 3.31 | -5.68 |
| NVO Novo Nordisk A/S |
0.41 1.00% |
41.10 | 41.58 | 31.15 | 2.13 | 32.99 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-0.86 0.16% |
547.03 | 30.22 | 24.27 | 10.36 | 6.50 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
43.35 4.73% |
959.41 | 29.07 | 20.12 | 7.57 | 3.82 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 36.06 |
Aura Biosciences, Inc., a clinical-stage biotechnology company, develops precision therapies to treat solid tumors. The company's proprietary platform enables the targeting of a range of solid tumors using virus-like particles conjugated with drugs or loaded with nucleic acids to create virus-like drug conjugates. Its lead candidate is bel-sar, which is in late-stage clinical development for the treatment of patients with primary choroidal melanoma and other ocular oncology indications, as well as in early-stage clinical development in bladder cancer. It focuses on assessing the safety and efficacy of bel-sar in treating a range of other solid tumors, including bladder cancer. The company was incorporated in 2009 and is headquartered in Boston, Massachusetts.
| Name | Title | Year Born |
|---|---|---|
| Dr. Elisabet de los Pinos Ph.D. | Founder, CEO, Pres & Director | 1974 |
| Ms. Julie B. Feder | CFO, Sec. & Treasurer | 1970 |
| Dr. Cadmus Collins Rich CPE, M.B.A., M.D., MBA | Chief Medical Officer and Head of R&D | 1965 |
| Dr. Mark A. De Rosch Ph.D. | Chief Operating Officer | 1964 |
| Mr. Paulo Carvalho | VP of Technical Operations | NA |
| Mr. Joseph Lyons | VP of HR | NA |
| Ms. Michele Keough M.B.A. | Sr. VP of Project Management and Device Supply Chain | NA |
| Dr. Elisabet de los Pinos Ph.D. | Founder, CEO, President & Director | 1973 |
| Ms. Julie B. Feder | CFO, Secretary & Treasurer | 1970 |
| Dr. Mark Plavsic D.V.M., Ph.D. | Chief Technology Officer | 1962 |
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