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Definium Therapeutics, Inc., a clinical biopharmaceutical company, develops novel product candidates to treat brain health disorders. The company's lead product candidates DT120, which is in phase 3 for the treatment of generalized anxiety disorder, major depressive disorder, and other brain health disorders; and DT402, a R-enantiomer of 3,4-methylenedioxymethamphetamine, which is in phase 2a clinical trials for the treatment of autism spectrum disorder. The company was formerly known as Mind Medicine (MindMed) Inc. and changed its name to Definium Therapeutics, Inc. in January 2026. Definium Therapeutics, Inc. is headquartered in New York, New York.
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Definium Therapeutics, Inc. is a NASDAQ-listed biotechnology company; publicly available disclosures provide limited detail on its pipeline and commercial strategy. As a clinical-stage biopharma, long-term growth may be driven by successful clinical trial results, regulatory approvals and strategic partnerships, a profile that may attract investors seeking exposure to potential upside from therapeutic development.
The most important investment risks are clinical and regulatory failure, the need for ongoing financing leading to dilution, and operational and market volatility common to early-stage biotech ventures, which investors should monitor.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -183.79M | -108.68M | -95.73M | -56.80M | -94.19M |
| Net income | -183.79M | -108.68M | -95.73M | -56.80M | -93.04M |
| Selling general administrative | 48.64M | 38.62M | 41.74M | 30.16M | 59.06M |
| Gross profit | - | -0.53M | -3.16M | - | - |
| Reconciled depreciation | 0.00M | 0.53M | 3.16M | 3.18M | 2.62M |
| Ebit | - | -106.40M | -95.73M | -66.33M | -93.85M |
| Ebitda | -178.31M | -105.87M | -92.57M | -63.15M | -91.24M |
| Depreciation and amortization | - | 0.53M | 3.16M | 3.18M | 2.62M |
| Operating income | -166.31M | -103.92M | -93.87M | -66.33M | -93.85M |
| Other operating expenses | 166.31M | 103.92M | 93.87M | 66.33M | 93.85M |
| Interest expense | 5.48M | 2.28M | 0.92M | 1.50M | 0.36M |
| Tax provision | - | - | - | 0.00M | -1.16M |
| Interest income | 10.96M | 11.56M | 5.58M | - | - |
| Net interest income | 5.48M | 9.28M | 4.66M | 1.50M | -0.36M |
| Income tax expense | - | - | - | - | -1.16M |
| Total revenue | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 166.31M | 103.39M | 90.70M | 66.33M | 93.85M |
| Cost of revenue | - | 0.53M | 3.16M | - | - |
| Total other income expense net | -17.48M | -4.76M | -1.87M | 9.54M | -0.34M |
| Net income from continuing ops | -183.79M | -108.68M | -95.73M | -56.80M | -93.04M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 440.10M | 302.15M | 124.54M | 169.99M | 164.00M |
| Intangible assets | - | - | 0.53M | 3.69M | 6.87M |
| Other current assets | 7.73M | 7.88M | 4.17M | 3.91M | 3.68M |
| Total liab | 107.77M | 60.70M | 46.41M | 19.08M | 12.34M |
| Total stockholder equity | 332.33M | 241.45M | 78.13M | 150.92M | 151.66M |
| Other current liab | 61.35M | 36.84M | 28.11M | 15.71M | 6.23M |
| Capital stock | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Retained earnings | -582.67M | -398.88M | -290.20M | -194.47M | -137.67M |
| Good will | 19.92M | 19.92M | 19.92M | 19.92M | 19.92M |
| Cash | 257.84M | 273.74M | 99.70M | 142.14M | 133.54M |
| Total current liabilities | 66.70M | 38.85M | 32.25M | 17.89M | 10.41M |
| Net debt | -257.84M | -251.89M | -85.58M | -142.07M | -133.54M |
| Short term debt | - | - | - | 0.07M | - |
| Short long term debt total | - | 21.85M | 14.13M | 0.07M | - |
| Other stockholder equity | 913.91M | 639.51M | 367.99M | 344.76M | 288.29M |
| Total current assets | 419.32M | 281.62M | 103.87M | 146.06M | 137.22M |
| Short term investments | 153.76M | 0.00M | - | - | - |
| Long term debt | 40.58M | 21.85M | 14.13M | - | - |
| Accounts payable | 5.35M | 2.01M | 4.14M | 2.11M | 4.18M |
| Accumulated other comprehensive income | 1.08M | 0.82M | 0.34M | 0.63M | 1.05M |
| Non currrent assets other | 0.86M | 0.61M | 0.22M | 0.33M | - |
| Non current assets total | 20.78M | 20.53M | 20.67M | 23.94M | 26.79M |
| Capital lease obligations | - | - | - | 0.07M | 0.00M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | -151.61M | 0.00M | - | - | - |
| Total cashflows from investing activities | -151.61M | - | - | - | -0.30M |
| Net borrowings | 20.00M | 10.86M | 21.68M | 0.00M | - |
| Total cash from financing activities | 267.27M | 253.20M | 21.85M | 59.05M | 98.82M |
| Net income | -183.79M | -108.68M | -95.73M | -56.80M | -93.04M |
| Change in cash | -15.90M | 174.04M | -42.44M | 8.60M | 53.45M |
| Begin period cash flow | 273.74M | 99.70M | 142.14M | 133.54M | 80.09M |
| End period cash flow | 257.84M | 273.74M | 99.70M | 142.14M | 133.54M |
| Total cash from operating activities | -131.56M | -79.13M | -64.36M | -50.14M | -45.82M |
| Issuance of capital stock | 258.86M | 250.00M | 0.00M | 42.30M | 81.92M |
| Depreciation | 0.00M | 0.53M | 3.16M | 3.18M | 2.62M |
| Other cashflows from financing activities | 267.27M | -7.66M | 0.16M | 16.75M | 16.90M |
| Capital expenditures | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Change in working capital | 9.44M | -3.34M | 6.28M | -3.78M | 1.88M |
| Stock based compensation | 20.10M | 16.91M | 15.49M | 13.71M | 42.72M |
| Other non cash items | 22.70M | 15.45M | 8.46M | -6.45M | 1.16M |
| Free cash flow | -131.56M | -79.13M | -64.36M | -50.14M | -45.82M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
|---|---|---|---|---|---|---|
| DFTX Definium Therapeutics, Inc. |
1.30 3.92% |
34.58 | - | - | - | 6.95 |
| NVO Novo Nordisk A/S |
0.47 1.18% |
40.78 | 41.58 | 31.15 | 2.13 | 32.99 |
| VRTX Vertex Pharmaceuticals Inc |
0.34 0.06% |
547.43 | 30.22 | 24.27 | 10.36 | 6.50 |
| REGN Regeneron Pharmaceuticals Inc |
8.76 0.97% |
913.11 | 29.07 | 20.12 | 7.57 | 3.82 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 |
Definium Therapeutics, Inc., a clinical biopharmaceutical company, develops novel product candidates to treat brain health disorders. The company's lead product candidates DT120, which is in phase 3 for the treatment of generalized anxiety disorder, major depressive disorder, and other brain health disorders; and DT402, a R-enantiomer of 3,4-methylenedioxymethamphetamine, which is in phase 2a clinical trials for the treatment of autism spectrum disorder. The company was formerly known as Mind Medicine (MindMed) Inc. and changed its name to Definium Therapeutics, Inc. in January 2026. Definium Therapeutics, Inc. is headquartered in New York, New York.
| Name | Title | Year Born |
|---|---|---|
| Mr. Robert Barrow | CEO & Director | 1990 |
| Mr. Mark R. Sullivan J.D. | Chief Legal Officer & Corporate Secretary | 1971 |
| Dr. Daniel Rollings Karlin M.A., M.D. | Chief Medical Officer | 1981 |
| Dr. Scott M. Freeman M.D. | Co-Founder & Clinical Advisor | 1957 |
| Mr. Leonard Latchman | Co-Founder | NA |
| Ms. Brandi L. Roberts CPA, M.B.A. | Chief Financial Officer | 1974 |
| Mr. Peter Mack | Senior Vice President of Pharmaceutical Development & Operations | NA |
| Ms. Gitanjali Jain Ogawa | VP & Head of Investor Relations | NA |
| Ms. Beth Calitri | Vice President of Corporate Communications | NA |
| Ms. Stephanie Fagan M.S. | Chief Corporate Affairs Officer | NA |
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