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Immunocore Holdings plc, together with its subsidiaries, engages in the development and commercialization of immunomodulating medicines for patients with cancer, infectious diseases, and autoimmune disease in the United States, Europe, and internationally. The company offers KIMMTRAK for the treatment of unresectable or metastatic uveal melanoma. It also develops oncology programs, including tebentafusp which is in Phase 3 clinical trial for the treatment of advanced cutaneous melanoma and adjuvant uveal melanoma; brenetafusp which is in Phase 3 clinical trial for the treatment of first-line advanced cutaneous melanoma and in Phase 1/2 clinical trial for the treatment of various tumor types; IMC-R117C which is in Phase 1/2 clinical trial for the treatment of advanced solid tumors, such as colorectal cancer; and IMC-P115C which is in Phase 1 clinical trial for patients with tumors that express PRAME. In addition, the company is involved in the development of IMC-M113V which is in Phase 1 clinical trial for a potential functional cure of human immunodeficiency virus; and IMC-I109V which is in Phase 1 clinical trial for a potential functional cure of hepatitis B virus. Further, it develops IMC-S118AI which is in pre-investigation stage for the treatment of type 1 diabetes; and IMC-U120AI which is in pre-investigation stage for the treatment of atopic dermatitis. The company was founded in 1999 and is headquartered in Abingdon, the United Kingdom.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
Immunocore Holdings Ltd develops T‑cell receptor–based bispecific therapies via its ImmTAC platform to redirect T cells against intracellular cancer and infectious disease targets. Long-term growth drivers include commercialization of existing products, pipeline expansion and partnerships, and the company may appeal to investors because the platform has achieved regulatory validation and targets antigens that are difficult to address with conventional approaches.
Key risks are dependence on a single marketed therapy with a genetically limited addressable population (HLA‑A*02:01), high clinical and regulatory risk across the pipeline, competitive pressures, and the need for additional financing and commercial execution.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -14.21M | -42.32M | -48.19M | -44.15M | -140.93M |
| Net income | -26.42M | -40.81M | -43.75M | -41.22M | -131.52M |
| Selling general administrative | 165.41M | 155.78M | 154.85M | 93.72M | 88.40M |
| Gross profit | 291.36M | 242.44M | 196.57M | 143.28M | 26.52M |
| Reconciled depreciation | 3.27M | 4.20M | 5.31M | 6.13M | 7.01M |
| Ebit | -2.04M | -41.86M | -44.11M | -39.61M | -135.16M |
| Ebitda | 0.39M | -38.50M | -40.87M | -36.45M | -135.12M |
| Depreciation and amortization | 2.43M | 3.36M | 3.24M | 3.15M | 0.05M |
| Operating income | -33.74M | -56.28M | -47.20M | -39.61M | -135.16M |
| Other operating expenses | 331.31M | 304.31M | 244.59M | 183.34M | 161.68M |
| Interest expense | 12.17M | 18.84M | 4.08M | 7.69M | 5.81M |
| Tax provision | 16.41M | -1.85M | 2.37M | -2.92M | -9.40M |
| Interest income | 16.48M | 25.62M | 12.48M | 3.15M | 0.05M |
| Net interest income | 4.31M | 6.77M | 4.48M | -4.54M | -5.77M |
| Income tax expense | 12.21M | -1.48M | -4.43M | -2.92M | -9.40M |
| Total revenue | 297.57M | 247.98M | 197.39M | 143.74M | 26.52M |
| Total operating expenses | 325.09M | 298.77M | 243.77M | 182.89M | 161.68M |
| Cost of revenue | 6.21M | 5.54M | 0.82M | 0.45M | - |
| Total other income expense net | 19.53M | 14.01M | -0.98M | -4.54M | -5.77M |
| Net income from continuing ops | -35.51M | -51.09M | -54.07M | -41.22M | -131.52M |
| Net income applicable to common shares | - | - | - | -41.22M | -131.52M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 1067.27M | 1009.51M | 597.00M | 435.52M | 301.77M |
| Intangible assets | - | - | - | 0.00M | - |
| Other current assets | 51.87M | 20.95M | 9.71M | 0.06M | 7.69M |
| Total liab | 686.24M | 648.79M | 228.16M | 156.76M | 130.23M |
| Total stockholder equity | 381.03M | 360.72M | 368.84M | 278.76M | 171.55M |
| Other current liab | 219.74M | 185.53M | 114.32M | 0.05M | 0.04M |
| Common stock | 0.14M | 0.14M | 0.14M | 0.10M | 0.09M |
| Capital stock | 0.14M | 0.14M | 0.14M | 0.10M | 0.09M |
| Retained earnings | -831.27M | -795.76M | -744.67M | -261.25M | -481.39M |
| Other liab | - | - | - | 5.92M | 6.46M |
| Good will | - | - | - | 0.41M | - |
| Other assets | - | - | - | 11.58M | 7.51M |
| Cash | 467.71M | 455.73M | 442.63M | 332.54M | 237.89M |
| Total current liabilities | 246.70M | 212.18M | 139.02M | 83.09M | 61.18M |
| Current deferred revenue | 0.58M | 5.43M | 5.51M | 6.41M | 24.45M |
| Net debt | -31.02M | -23.01M | -358.59M | -263.24M | -174.05M |
| Short term debt | 2.01M | 1.55M | 1.39M | 1.55M | 1.25M |
| Short long term debt total | 436.69M | 432.72M | 84.03M | 69.30M | 63.84M |
| Other stockholder equity | 1240.26M | 1190.11M | 1149.64M | 205.16M | 266.60M |
| Property plant equipment | - | - | - | 31.64M | 31.54M |
| Total current assets | 996.74M | 929.86M | 528.82M | 391.88M | 262.73M |
| Long term investments | - | - | - | 0.14M | 0.17M |
| Net tangible assets | - | - | - | 278.35M | 171.55M |
| Short term investments | 396.44M | 364.64M | - | - | - |
| Net receivables | 73.98M | 83.10M | 61.44M | 58.40M | 24.84M |
| Long term debt | 393.12M | 391.01M | 48.01M | 39.50M | 37.23M |
| Inventory | 6.74M | 5.45M | 4.50M | 0.94M | -7.69M |
| Accounts payable | 24.36M | 25.10M | 17.80M | 75.08M | 35.44M |
| Accumulated other comprehensive income | -28.08M | -33.76M | -36.26M | 334.75M | 386.26M |
| Non currrent assets other | 20.28M | 17.12M | 14.47M | 7.21M | 4.77M |
| Non current assets total | 70.53M | 79.64M | 68.18M | 43.64M | 39.05M |
| Capital lease obligations | 43.56M | 41.71M | 36.02M | 29.80M | 26.61M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | -12.00M | -355.13M | 4.79M | 0.19M | -0.37M |
| Change to liabilities | - | - | - | 18.63M | 9.47M |
| Total cashflows from investing activities | -12.16M | -355.13M | -4.29M | 0.19M | -0.37M |
| Net borrowings | 0.00M | 352.50M | 0.00M | -3.21M | -3.16M |
| Total cash from financing activities | 9.20M | 343.88M | 27.18M | 138.23M | 276.25M |
| Change to operating activities | - | - | - | 0.58M | -21.28M |
| Net income | -26.42M | -51.09M | -34.32M | -41.22M | -131.52M |
| Change in cash | 8.89M | 13.11M | 31.78M | 114.31M | 146.03M |
| Begin period cash flow | 338.23M | 442.63M | 318.50M | 287.30M | 175.12M |
| End period cash flow | 347.11M | 455.73M | 350.27M | 401.61M | 321.15M |
| Total cash from operating activities | -7.97M | 26.06M | 2.33M | -31.27M | -129.75M |
| Issuance of capital stock | 0.00M | 0.00M | 0.00M | 116.81M | 226.53M |
| Depreciation | 2.43M | 4.20M | 3.24M | 6.13M | 7.01M |
| Other cashflows from investing activities | 4.18M | 0.04M | -0.93M | 2.38M | 0.56M |
| Dividends paid | - | - | 0.00M | 0.00M | 0.00M |
| Change to inventory | - | - | 29.04M | - | - |
| Change to account receivables | -5.46M | -12.35M | -14.14M | -32.09M | -5.15M |
| Other cashflows from financing activities | 3.17M | -15.42M | 27.18M | 68.13M | 52.88M |
| Change to netincome | - | - | - | 22.09M | 45.36M |
| Capital expenditures | 3.23M | 5.17M | 4.29M | 2.20M | 1.01M |
| Change in working capital | -6.92M | 45.13M | 4.58M | -12.88M | -16.81M |
| Stock based compensation | 37.70M | 34.19M | 25.69M | 27.05M | 35.86M |
| Other non cash items | 11.94M | -6.38M | 3.14M | -7.42M | -14.89M |
| Free cash flow | -11.20M | 20.89M | -1.97M | -33.47M | -130.76M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| IMCR Immunocore Holdings Ltd |
0.28 0.88% |
32.01 | - | 24.39 | 3.80 | 3.98 | 2.85 | 94.05 |
| NVO Novo Nordisk A/S |
-0.79 1.90% |
40.59 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-1.97 0.36% |
548.90 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
-9.49 1.03% |
910.47 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Immunocore Holdings plc, together with its subsidiaries, engages in the development and commercialization of immunomodulating medicines for patients with cancer, infectious diseases, and autoimmune disease in the United States, Europe, and internationally. The company offers KIMMTRAK for the treatment of unresectable or metastatic uveal melanoma. It also develops oncology programs, including tebentafusp which is in Phase 3 clinical trial for the treatment of advanced cutaneous melanoma and adjuvant uveal melanoma; brenetafusp which is in Phase 3 clinical trial for the treatment of first-line advanced cutaneous melanoma and in Phase 1/2 clinical trial for the treatment of various tumor types; IMC-R117C which is in Phase 1/2 clinical trial for the treatment of advanced solid tumors, such as colorectal cancer; and IMC-P115C which is in Phase 1 clinical trial for patients with tumors that express PRAME. In addition, the company is involved in the development of IMC-M113V which is in Phase 1 clinical trial for a potential functional cure of human immunodeficiency virus; and IMC-I109V which is in Phase 1 clinical trial for a potential functional cure of hepatitis B virus. Further, it develops IMC-S118AI which is in pre-investigation stage for the treatment of type 1 diabetes; and IMC-U120AI which is in pre-investigation stage for the treatment of atopic dermatitis. The company was founded in 1999 and is headquartered in Abingdon, the United Kingdom.
| Name | Title | Year Born |
|---|---|---|
| Dr. Bahija Jallal Ph.D. | CEO & Director | 1962 |
| Mr. Brian R. Di Donato M.B.A. | CFO & Head of Strategy | 1967 |
| Ms. Annelise Vuidepot Ph.D. | CTO and Head of Pipeline & Platform Research | NA |
| Clayton Robertson | Head of Investor Relations | NA |
| Ms. Lily Hepworth | Gen. Counsel & Company Sec. | NA |
| Ms. Amy Judge-Prein | Chief Compliance Officer | NA |
| Mr. Sébastien Desprez | Head of Communications | NA |
| Ms. Tina St. Leger | Chief HR Officer | 1969 |
| Dr. David Berman M.D., Ph.D. | Head of R&D | 1971 |
| Ms. Debra Nielsen | Chief of Staff | NA |
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