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Janux Therapeutics, Inc., a clinical stage biopharmaceutical company, develops immunotherapies based on Tumor Activated T Cell Engagers (TRACTr) and Tumor Activated Immunomodulators (TRACIr) platforms technology to treat patients suffering from cancer. The company's clinical candidates comprise JANX007, a prostate-specific membrane antigen or PSMA-TRACTr, which is in Phase 1 clinical trial in adults for the treatment of metastatic castration-resistant prostate cancer (mCRPC) and the vasculature of other tumors; and JANX008, an epidermal growth factor receptor or EGFR-TRACTr that is in Phase 1 clinical trial for the treatment of multiple solid cancers, including colorectal cancer, squamous cell carcinoma of the head and neck, non-small cell lung cancer, and renal cell carcinoma. Its development pipeline also consists of discovery stage products. The company has strategic research collaboration agreement with Merck Sharp & Dohme Corp. to develop TRACTr product candidates. Janux Therapeutics, Inc. was incorporated in 2017 and is headquartered in San Diego, California.
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Janux Therapeutics is a clinical-stage biotechnology company developing tumor-targeted cytokine immunotherapies using a proprietary delivery platform designed to concentrate immunostimulatory cytokines in the tumor microenvironment to enhance local activity and limit systemic exposure. Long-term growth drivers include clinical development progress, potential to improve the therapeutic index of cytokine treatments in oncology, and successful regulatory or partnership outcomes. The company could appeal to investors seeking exposure to a differentiated approach in cancer immunotherapy with the possibility of addressing unmet needs in solid tumors.
Key risks include significant clinical and regulatory uncertainty, high cash burn with likely future financing and dilution, and strong competition in oncology therapeutics.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Income before tax | -63.06M | -32.67M | -6.78M | -4.00M |
| Net income | -54.15M | -32.56M | -5.25M | -4.24M |
| Selling general administrative | 22.26M | 10.33M | 1.80M | 0.77M |
| Gross profit | 8.61M | 3.64M | - | - |
| Reconciled depreciation | 0.84M | 0.11M | 0.01M | 0.01M |
| Ebit | -67.93M | -33.04M | -4.84M | -3.77M |
| Ebitda | -67.09M | -32.93M | -6.57M | -3.77M |
| Depreciation and amortization | 0.84M | 0.11M | -1.72M | 0.01M |
| Non operating income net other | 4.03M | 0.26M | - | - |
| Operating income | -67.09M | -32.93M | -4.84M | -3.77M |
| Other operating expenses | 75.70M | 36.57M | 4.84M | 3.77M |
| Interest expense | 4.03M | 0.37M | 0.21M | 0.23M |
| Interest income | 4.03M | 0.26M | - | - |
| Net interest income | 4.03M | 0.26M | -0.21M | -0.23M |
| Income tax expense | -8.90M | -0.11M | -1.53M | 0.23M |
| Total revenue | 8.61M | 3.64M | 0.00M | 0.00M |
| Total operating expenses | 75.70M | 36.57M | 4.84M | 3.77M |
| Cost of revenue | 75.70M | 36.57M | - | - |
| Total other income expense net | 4.03M | 0.26M | -1.94M | -0.23M |
| Net income from continuing ops | -63.06M | -32.67M | -6.78M | -4.00M |
| Net income applicable to common shares | -63.06M | -32.67M | -6.78M | -4.00M |
| Breakdown | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Total assets | 380.41M | 364.01M | 379.82M | 16.22M | 0.68M |
| Other current assets | 5.21M | 5.42M | 2.05M | 0.25M | - |
| Total liab | 36.06M | 43.27M | 13.50M | 30.86M | 8.62M |
| Total stockholder equity | 344.35M | 320.74M | 366.33M | -14.64M | -7.94M |
| Other current liab | 7.39M | 8.18M | 4.98M | 0.05M | 0.36M |
| Common stock | 0.05M | 0.04M | 0.04M | 0.00M | 0.00M |
| Capital stock | 0.05M | 0.04M | 0.04M | 0.00M | 0.00M |
| Retained earnings | -168.76M | -110.47M | -47.41M | -14.74M | -7.96M |
| Other liab | - | 2.22M | 0.70M | 6.05M | - |
| Other assets | - | 2.21M | 1.21M | - | - |
| Cash | 19.20M | 51.43M | 35.58M | 7.81M | 0.66M |
| Total current liabilities | 13.03M | 16.51M | 12.80M | 3.18M | 4.63M |
| Current deferred revenue | 1.71M | 5.41M | 5.16M | 1.95M | - |
| Net debt | 5.34M | -26.12M | -35.39M | -7.81M | 3.34M |
| Short term debt | 1.52M | 0.76M | 0.19M | 0.75M | 4.00M |
| Short long term debt | - | - | - | - | 4.00M |
| Short long term debt total | 24.54M | 25.30M | 0.19M | - | 4.00M |
| Other stockholder equity | 512.40M | 432.70M | 34.14M | 0.10M | 0.01M |
| Property plant equipment | - | 7.09M | 1.60M | 0.15M | 0.02M |
| Total current assets | 349.24M | 332.44M | 377.02M | 16.06M | 0.66M |
| Net tangible assets | - | 320.74M | 366.33M | -14.64M | -7.94M |
| Short term investments | 324.82M | 275.59M | 339.38M | - | - |
| Net receivables | 2.20M | 0.70M | 0.20M | 8.00M | 0.00M |
| Inventory | -2.20M | - | - | - | - |
| Accounts payable | 2.42M | 2.16M | 2.46M | 0.43M | 0.27M |
| Accumulated other comprehensive income | 0.67M | -1.53M | -0.27M | - | - |
| Common stock total equity | - | 0.04M | 0.04M | 0.00M | 0.00M |
| Retained earnings total equity | - | -110.47M | -47.41M | - | - |
| Non currrent assets other | 3.33M | 2.21M | 1.21M | - | - |
| Non current assets total | 31.17M | 31.57M | 2.81M | 0.15M | 0.02M |
| Capital lease obligations | 24.54M | 25.30M | 0.19M | - | - |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Investments | 64.71M | -339.48M | -339.48M | -339.48M |
| Change to liabilities | 5.63M | 0.00M | 8.01M | 0.00M |
| Total cashflows from investing activities | 58.27M | -340.96M | -340.96M | -340.96M |
| Net borrowings | 23.42M | 180.55M | 2.50M | 4.00M |
| Total cash from financing activities | 0.50M | 386.52M | 11.52M | 4.00M |
| Change to operating activities | 2.81M | 0.84M | 0.38M | -0.07M |
| Net income | -63.06M | -32.67M | -6.78M | -4.00M |
| Change in cash | 15.84M | 28.59M | 7.16M | 0.17M |
| Begin period cash flow | 36.40M | 7.81M | 0.66M | 0.49M |
| End period cash flow | 52.24M | 36.40M | 7.81M | 0.66M |
| Total cash from operating activities | -42.92M | -16.98M | -4.37M | -3.83M |
| Issuance of capital stock | 0.00M | 384.71M | 8.95M | 0.00M |
| Depreciation | 0.84M | 0.11M | 0.01M | 0.01M |
| Change to inventory | - | 0.83M | 0.38M | - |
| Change to account receivables | 0.00M | 8.00M | -8.00M | -8.00M |
| Sale purchase of stock | - | 204.17M | - | - |
| Other cashflows from financing activities | 58.27M | 182.36M | 11.52M | 4.00M |
| Change to netincome | 17.20M | 6.74M | 2.01M | 0.24M |
| Capital expenditures | 6.45M | 1.48M | 1.48M | 1.48M |
| Change receivables | - | 8.00M | - | - |
| Cash flows other operating | -1.35M | -2.19M | - | - |
| Cash and cash equivalents changes | 15.84M | 28.59M | - | - |
| Change in working capital | 4.28M | 8.84M | 0.39M | -0.07M |
| Stock based compensation | 17.20M | 6.91M | 0.07M | 0.01M |
| Other non cash items | -2.18M | -0.17M | 1.94M | 0.23M |
| Free cash flow | -49.37M | -18.46M | -4.37M | -3.83M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| JANX Janux Therapeutics Inc |
-0.39 3.06% |
12.37 | - | - | 336.50 | 7.90 | 296.97 | -33.80 |
| NVO Novo Nordisk A/S |
-0.70 1.70% |
40.67 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-0.79 0.14% |
550.08 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
-6.17 0.67% |
913.79 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Janux Therapeutics, Inc., a clinical stage biopharmaceutical company, develops immunotherapies based on Tumor Activated T Cell Engagers (TRACTr) and Tumor Activated Immunomodulators (TRACIr) platforms technology to treat patients suffering from cancer. The company's clinical candidates comprise JANX007, a prostate-specific membrane antigen or PSMA-TRACTr, which is in Phase 1 clinical trial in adults for the treatment of metastatic castration-resistant prostate cancer (mCRPC) and the vasculature of other tumors; and JANX008, an epidermal growth factor receptor or EGFR-TRACTr that is in Phase 1 clinical trial for the treatment of multiple solid cancers, including colorectal cancer, squamous cell carcinoma of the head and neck, non-small cell lung cancer, and renal cell carcinoma. Its development pipeline also consists of discovery stage products. The company has strategic research collaboration agreement with Merck Sharp & Dohme Corp. to develop TRACTr product candidates. Janux Therapeutics, Inc. was incorporated in 2017 and is headquartered in San Diego, California.
10955 Vista Sorrento Parkway, San Diego, CA, United States, 92130
858-751-4493
68
| Name | Title | Year Born |
|---|---|---|
| Dr. David Alan Campbell Ph.D. | Pres, CEO & Director | 1960 |
| Dr. Wayne Godfrey M.D. | Chief Medical Officer | 1961 |
| Mr. Tighe M. Reardon C.F.A., CPA, CPA | Acting Chief Financial Officer | 1976 |
| Mr. Tommy Diraimondo Ph.D. | Sr. Director of Research | NA |
| Ms. Brenda Van Vreeswyk | Head of HR | NA |
| Mr. Andy Hollman Meyer | Chief Bus. Officer | 1984 |
| Mr. Charles M. Winter | Sr. VP of Chemistry, Manufacturing & Controls | NA |
| Mr. Byron Robinson J.D., Ph.D. | Chief Strategy Officer | 1965 |
| Dr. David Alan Campbell Ph.D. | President, CEO & Director | 1960 |
| Mr. Tighe M. Reardon C.F.A., CPA | Acting Chief Financial Officer | 1977 |
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