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Personalis, Inc. develops and markets advanced cancer genomic tests and analytics primarily in the United States, Europe, and the Asia-Pacific. Its tests and analytics are used by pharmaceutical companies for translational research, biomarker discovery, and development of personalized cancer therapies, as well as advanced tests are used by physicians to detect cancer recurrence, monitor cancer evolution, and uncover insights for therapy selection. The company offers NeXT Personal, a tumor-informed liquid biopsy test for detection of minimal residual disease (MRD) and recurrence in cancer; and ImmunoID NeXT, a tissue-based test that combines whole exome (DNA) and whole transcriptome (RNA) sequencing data with advanced analytics to provide a multi-dimensional view of the tumor and the tumor microenvironment from a single sample. It also provides NeXT Personal Dx, a tumor-informed liquid biopsy test for detection of MRD and recurrence in cancer; and NeXT Dx, a comprehensive tumor profiling test that unlocks the entire exome (DNA) and transcriptome (RNA) with matched tumor-normal analysis. In addition, the company performs whole exome sequencing (WES) of cancer tissue and matched blood samples for diagnostic companies as an input to their products; and whole genome sequencing (WGS) on human samples for research projects, such as population sequencing initiatives, as well as offers sequencing and data analysis services to support population sequencing initiatives. Its customers include pharmaceutical companies, biopharmaceutical companies, diagnostics companies, universities, non-profits, government entities, and patients. The company was incorporated in 2011 and is headquartered in Fremont, California.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
Personalis provides genome-scale sequencing and analytics to support precision oncology and immunotherapy development for biopharma and clinical research customers. Long-term growth may be supported by rising demand for neoantigen discovery, biomarker-driven trials and outsourcing of complex genomic assays; Personalis appears positioned to benefit from its assays and analytics that could generate recurring collaboration and commercial revenue.
Material risks include intense competition from larger diagnostics and sequencing companies, dependence on biopharma partnerships and clinical adoption, regulatory and reimbursement uncertainty, and the potential need for additional financing to fund ongoing operations.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Income before tax | -113.28M | -65.21M | -41.22M | -25.07M | -19.88M |
| Minority interest | - | - | - | - | 0.00M |
| Net income | -113.31M | -65.23M | -41.28M | -25.08M | -19.89M |
| Selling general administrative | 63.97M | 47.70M | 33.69M | 22.08M | 11.27M |
| Gross profit | 13.35M | 31.66M | 20.11M | 22.08M | 11.80M |
| Reconciled depreciation | 8.43M | 6.01M | 5.76M | 4.75M | 3.07M |
| Ebit | -115.53M | -65.35M | -42.15M | -22.42M | -13.51M |
| Ebitda | -113.07M | -65.03M | -35.46M | -22.24M | -10.44M |
| Depreciation and amortization | 2.46M | 0.33M | 6.68M | 0.18M | 3.07M |
| Non operating income net other | 2.46M | 0.33M | 0.93M | - | - |
| Operating income | -115.53M | -65.35M | -42.15M | -22.42M | -13.77M |
| Other operating expenses | 180.58M | 150.85M | 120.79M | 87.62M | 51.54M |
| Interest expense | 0.20M | 0.18M | 0.00M | 1.13M | 1.89M |
| Tax provision | 0.04M | 0.01M | 0.06M | 0.01M | 0.01M |
| Interest income | 2.40M | 0.37M | 0.95M | 1.62M | 0.29M |
| Net interest income | 2.19M | 0.18M | 0.95M | 0.49M | -1.60M |
| Extraordinary items | - | - | - | - | 0.00M |
| Non recurring | - | - | - | - | 0.00M |
| Other items | - | - | - | - | 0.00M |
| Income tax expense | 0.04M | 0.01M | 0.06M | 0.01M | 0.01M |
| Total revenue | 65.05M | 85.49M | 78.65M | 65.21M | 37.77M |
| Total operating expenses | 128.88M | 97.01M | 62.26M | 44.50M | 25.57M |
| Cost of revenue | 51.70M | 53.84M | 58.53M | 43.13M | 25.97M |
| Total other income expense net | 2.26M | 0.14M | 0.92M | -2.66M | -4.51M |
| Discontinued operations | - | - | - | - | 0.00M |
| Net income from continuing ops | -113.31M | -65.23M | -41.28M | -25.08M | -19.89M |
| Net income applicable to common shares | -113.31M | -65.23M | -41.28M | -25.08M | -19.89M |
| Breakdown | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Total assets | 225.10M | 292.70M | 396.53M | 244.84M | 157.29M |
| Other current assets | 4.36M | 6.81M | 7.09M | 5.44M | 3.38M |
| Total liab | 95.66M | 74.56M | 86.23M | 49.90M | 50.60M |
| Total stockholder equity | 129.44M | 218.14M | 310.30M | 194.94M | 106.69M |
| Other current liab | 19.62M | 11.40M | 12.58M | 8.86M | 5.29M |
| Common stock | 0.01M | 0.01M | 0.00M | 0.00M | 0.00M |
| Capital stock | 0.01M | 0.01M | 0.00M | 0.00M | 0.00M |
| Retained earnings | -468.71M | -360.41M | -247.09M | -181.87M | -140.59M |
| Other liab | - | 0.01M | 2.12M | 0.72M | - |
| Other assets | 0.00M | 4.59M | 4.83M | 12.29M | 1.76M |
| Cash | 56.98M | 89.13M | 105.58M | 68.53M | 55.05M |
| Total current liabilities | 47.23M | 33.13M | 31.31M | 40.64M | 49.96M |
| Current deferred revenue | 3.29M | 1.26M | 3.98M | 21.03M | 35.98M |
| Net debt | -8.02M | -40.48M | -52.79M | -57.54M | -53.69M |
| Short term debt | 9.41M | 7.61M | 5.53M | 2.44M | 1.36M |
| Short long term debt | 1.65M | 2.22M | 1.81M | - | - |
| Short long term debt total | 48.96M | 48.65M | 52.80M | 10.99M | 1.36M |
| Other stockholder equity | 598.36M | 579.46M | 557.56M | 376.79M | 89.99M |
| Property plant equipment | - | 61.94M | 19.65M | 11.83M | 15.95M |
| Total current assets | 141.93M | 199.70M | 318.23M | 220.72M | 139.58M |
| Net tangible assets | - | 218.14M | 310.30M | 194.94M | 106.69M |
| Short term investments | 57.20M | 78.53M | 181.48M | 134.76M | 73.24M |
| Net receivables | 17.73M | 16.64M | 18.47M | 6.35M | 3.30M |
| Inventory | 5.66M | 8.59M | 5.61M | 2.67M | 4.61M |
| Accounts payable | 14.92M | 12.85M | 9.22M | 8.30M | 7.34M |
| Accumulated other comprehensive income | -0.22M | -0.91M | -0.17M | 0.02M | -0.01M |
| Common stock total equity | - | 0.01M | 0.00M | 0.00M | 0.00M |
| Retained earnings total equity | - | -360.41M | -247.09M | -181.87M | - |
| Non currrent assets other | 6.16M | 4.59M | 4.83M | 2.02M | 1.76M |
| Non current assets total | 83.17M | 93.00M | 78.30M | 24.12M | 17.71M |
| Capital lease obligations | 46.08M | 46.43M | 52.80M | 10.99M | 2.00M |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Investments | 102.43M | -48.99M | -61.90M | -73.20M | -73.20M |
| Change to liabilities | 1.19M | 1.62M | 5.00M | -5.52M | 20.37M |
| Total cashflows from investing activities | 52.54M | -60.07M | -65.14M | -81.58M | -7.85M |
| Net borrowings | -1.10M | 3.31M | 3.31M | -5.00M | -0.65M |
| Total cash from financing activities | 1.37M | 169.70M | 121.27M | 134.95M | -0.59M |
| Change to operating activities | 11.40M | -0.55M | 1.09M | -1.64M | -0.37M |
| Net income | -113.31M | -65.23M | -41.28M | -25.08M | -19.89M |
| Change in cash | -16.46M | 38.85M | 13.48M | 35.30M | -2.87M |
| Begin period cash flow | 107.38M | 68.53M | 55.05M | 19.74M | 22.62M |
| End period cash flow | 90.92M | 107.38M | 68.53M | 55.05M | 19.74M |
| Total cash from operating activities | -70.23M | -70.83M | -42.65M | -18.07M | 5.57M |
| Issuance of capital stock | 0.00M | 162.26M | 117.50M | 144.71M | - |
| Depreciation | 8.43M | 6.01M | 5.76M | 4.75M | 3.07M |
| Other cashflows from investing activities | - | - | - | -73.20M | 0.00M |
| Dividends paid | - | - | - | - | 0.00M |
| Change to inventory | -2.98M | 0.03M | -1.08M | -1.17M | -2.07M |
| Change to account receivables | 1.82M | -12.12M | -3.05M | 1.07M | -2.52M |
| Sale purchase of stock | 2.46M | 166.39M | 121.27M | 145.42M | 0.08M |
| Other cashflows from financing activities | 3.66M | 9.30M | 3.77M | 15.24M | 0.05M |
| Change to netincome | 19.54M | 14.55M | 8.30M | 9.53M | 6.97M |
| Capital expenditures | 49.90M | 11.08M | 3.25M | 8.38M | 7.85M |
| Change receivables | 1.82M | -12.12M | -3.05M | - | - |
| Cash flows other operating | 12.10M | -15.66M | -17.38M | - | - |
| Cash and cash equivalents changes | -16.33M | 38.80M | 13.47M | - | - |
| Change in working capital | 10.61M | -31.14M | -17.23M | -7.26M | 15.42M |
| Stock based compensation | 19.43M | 14.38M | 8.24M | 4.86M | 1.32M |
| Other non cash items | 4.61M | 3.12M | 1.47M | 1.56M | 1.18M |
| Free cash flow | -120.13M | -81.91M | -45.90M | -26.45M | -2.28M |
Sector: Healthcare Industry: Diagnostics & Research
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| PSNL Personalis Inc |
0.08 0.50% |
15.96 | - | - | 0.89 | 0.50 | 0.05 | 0.01 |
| TMO Thermo Fisher Scientific Inc |
-0.49 0.07% |
717.71 | 34.71 | 23.87 | 4.62 | 4.43 | 5.29 | 20.89 |
| DHR Danaher Corporation |
-0.80 0.34% |
235.31 | 29.09 | 28.01 | 5.67 | 3.20 | 6.00 | 19.09 |
| WUXIF WuXi AppTec Co. Ltd |
- -% |
25.84 | 22.29 | 17.95 | 1.53 | 5.98 | 8.39 | 14.30 |
| WUXAY WuXi AppTec Co. Ltd |
-0.50 1.94% |
25.10 | 23.28 | 18.73 | 1.51 | 6.24 | 8.39 | 14.30 |
Personalis, Inc. develops and markets advanced cancer genomic tests and analytics primarily in the United States, Europe, and the Asia-Pacific. Its tests and analytics are used by pharmaceutical companies for translational research, biomarker discovery, and development of personalized cancer therapies, as well as advanced tests are used by physicians to detect cancer recurrence, monitor cancer evolution, and uncover insights for therapy selection. The company offers NeXT Personal, a tumor-informed liquid biopsy test for detection of minimal residual disease (MRD) and recurrence in cancer; and ImmunoID NeXT, a tissue-based test that combines whole exome (DNA) and whole transcriptome (RNA) sequencing data with advanced analytics to provide a multi-dimensional view of the tumor and the tumor microenvironment from a single sample. It also provides NeXT Personal Dx, a tumor-informed liquid biopsy test for detection of MRD and recurrence in cancer; and NeXT Dx, a comprehensive tumor profiling test that unlocks the entire exome (DNA) and transcriptome (RNA) with matched tumor-normal analysis. In addition, the company performs whole exome sequencing (WES) of cancer tissue and matched blood samples for diagnostic companies as an input to their products; and whole genome sequencing (WGS) on human samples for research projects, such as population sequencing initiatives, as well as offers sequencing and data analysis services to support population sequencing initiatives. Its customers include pharmaceutical companies, biopharmaceutical companies, diagnostics companies, universities, non-profits, government entities, and patients. The company was incorporated in 2011 and is headquartered in Fremont, California.
6600 Dumbarton Circle, Fremont, CA, United States, 94555
650 752 1300
223
| Name | Title | Year Born |
|---|---|---|
| Mr. John Stephen West | Co-Founder, CEO, Pres & Director | 1957 |
| Mr. Aaron L. Tachibana | Sr. VP & CFO | 1961 |
| Dr. Richard Chen M.D., M.S., MS | Sr. VP of R&D and Chief Medical Officer | 1971 |
| Dr. Russ B. Altman M.D., Ph.D. | Co-Founder and Member of Clinical & Scientific Advisory Board | NA |
| Dr. Euan A. Ashley DPHIL, FRCP, M.D., Ph.D. | Co-Founder and Member of Clinical & Scientific Advisory Board | 1972 |
| Dr. Atul Butte | Co-Founder and Member of Clinical & Scientific Advisory Board | NA |
| Dr. Michael Snyder Ph.D. | Co-Founder and Member of Clinical & Scientific Advisory Board | NA |
| Ms. Carol J. Tillis | VP of Fin. & Admin. | NA |
| Mr. Stephen M. Moore J.D. | VP, Gen. Counsel & Corp. Sec. | 1972 |
| Mr. Michael J Fitzpatrick | VP of Worldwide Sales | NA |
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