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UroGen Pharma Ltd., a biotechnology company, engages in the development and commercialization of solutions for urothelial and specialty cancers. It offers RTGel, a novel proprietary polymeric biocompatible, reverse thermal gelation hydrogel technology; Mitomycin a generic drug used off-label as an adjuvant chemotherapy for the treatment of low-grade NMIBC after trans-urethral resection of bladder tumor; Zusduri, a sustained-release formulation of mitomycin for the treatment of non-muscle invasive bladder cancer (NMIBC); and Jelmyto for pyelocalyceal solutions. The company's lead product candidates are UGN-103, which is in phase 3 of clinical trial for intravesical solution; and UGN-104 that is in phase 3 of clinical trial for pyelocalyceal solution designed for the treatment of several forms of non-muscle invasive urothelial cancer that include low-grade upper tract urothelial cancer and low-grade intermediate risk NMIBC. It is also developing UGN-301, UGN-301+UGN 201, and UGN-301+gemcitabine that are in phase 1 of clinical trial for the treatment of high-grade NMIBC. The company has license agreement with Agenus Inc. to develop, make, use, sell, import, and commercialize products of Agenus for the treatment of cancers of the urinary tract via intravesical delivery; and licensing and supply agreement with medac Gesellschaft für klinische Spezialpräparate m.b.H. to develop UGN-103 and UGN-104. UroGen Pharma Ltd. was incorporated in 2004 and is headquartered in Princeton, New Jersey.
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UroGen Pharma is a commercial-stage biopharmaceutical company developing and marketing urology therapies using a proprietary sustained-release RTGel delivery platform; its lead product JELMYTO (mitomycin gel) is approved for low-grade upper tract urothelial carcinoma. Long-term growth may be supported by increased clinical adoption of JELMYTO, label expansion opportunities, pipeline programs leveraging RTGel and international rollout. The company appears positioned to address an underserved, rare urologic indication with a differentiated delivery technology.
Material risks include concentrated revenue from a single approved product, commercial execution and reimbursement challenges, clinical and regulatory uncertainty for new indications, and potential financing or cash-runway constraints that investors should monitor.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -153.42M | -124.04M | -98.32M | -108.03M | -109.37M |
| Net income | -153.49M | -126.87M | -102.24M | -109.16M | -110.82M |
| Selling general administrative | 155.10M | 121.15M | 90.36M | 82.84M | 39.94M |
| Selling and marketing expenses | - | - | - | - | 47.59M |
| Gross profit | 97.34M | 81.52M | 73.35M | 56.70M | 42.88M |
| Reconciled depreciation | 2.41M | 1.19M | 1.73M | 1.82M | 1.77M |
| Ebit | -138.07M | -95.68M | -62.06M | -79.04M | -92.29M |
| Ebitda | -135.66M | -95.35M | -60.35M | -78.03M | -75.00M |
| Depreciation and amortization | 2.41M | 0.33M | 1.71M | 1.01M | 17.29M |
| Non operating income net other | - | - | - | 1.01M | 0.21M |
| Operating income | -124.86M | -96.78M | -65.54M | -79.04M | -92.29M |
| Other operating expenses | 234.65M | 187.18M | 148.25M | 143.40M | 140.33M |
| Interest expense | 33.85M | 12.52M | 14.71M | 8.44M | 32.60M |
| Tax provision | 0.08M | 2.83M | 0.76M | 1.75M | 1.45M |
| Interest income | 5.96M | 8.90M | 2.38M | 0.94M | 0.36M |
| Net interest income | -27.88M | -3.62M | -11.90M | -7.43M | 0.21M |
| Income tax expense | 0.08M | 2.83M | 3.92M | 1.14M | 1.45M |
| Total revenue | 109.79M | 90.40M | 82.71M | 64.36M | 48.04M |
| Total operating expenses | 222.20M | 178.30M | 138.89M | 135.74M | 135.18M |
| Cost of revenue | 12.45M | 8.88M | 9.36M | 7.65M | 5.16M |
| Total other income expense net | -28.55M | -27.26M | -32.79M | -28.99M | -17.08M |
| Net income from continuing ops | -153.49M | -126.87M | -105.10M | -109.78M | -110.82M |
| Net income applicable to common shares | - | - | - | -109.78M | -110.82M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 200.46M | 285.71M | 178.31M | 136.24M | 119.75M |
| Other current assets | 16.02M | 9.92M | 10.28M | 11.10M | 7.48M |
| Total liab | 305.93M | 294.51M | 243.52M | 224.98M | 111.33M |
| Total stockholder equity | -105.47M | -8.80M | -65.21M | -88.74M | 8.41M |
| Other current liab | 34.28M | 35.02M | 19.49M | 18.39M | 16.59M |
| Common stock | 0.13M | 0.12M | 0.09M | 0.06M | 0.06M |
| Capital stock | 0.13M | 0.12M | 0.09M | 0.06M | 0.06M |
| Retained earnings | -959.72M | -806.22M | -679.35M | -577.10M | -467.32M |
| Other liab | - | - | - | - | 88.56M |
| Other assets | - | - | - | 0.62M | 0.03M |
| Cash | 110.75M | 171.99M | 95.82M | 55.41M | 44.36M |
| Total current liabilities | 46.42M | 45.95M | 31.21M | 23.92M | 22.38M |
| Current deferred revenue | - | 5.15M | 4.39M | - | - |
| Net debt | 17.59M | -48.60M | 4.39M | 43.72M | -43.96M |
| Short term debt | - | 1.53M | 0.82M | - | - |
| Short long term debt total | 128.33M | 123.39M | 100.21M | 99.12M | 0.40M |
| Other stockholder equity | 854.09M | 797.25M | 614.03M | 488.41M | 475.70M |
| Property plant equipment | - | - | - | 1.30M | 1.97M |
| Total current assets | 186.02M | 276.13M | 169.19M | 128.91M | 114.39M |
| Long term investments | 0.00M | 5.02M | 4.50M | 0.00M | 0.68M |
| Net tangible assets | - | - | - | -89.36M | 8.41M |
| Short term investments | 9.71M | 64.70M | 41.97M | 44.56M | 44.78M |
| Net receivables | 33.08M | 20.30M | 15.44M | 12.70M | 11.72M |
| Long term debt | 122.21M | 121.73M | 98.55M | 97.54M | - |
| Inventory | 16.46M | 9.23M | 5.67M | 4.33M | 4.83M |
| Accounts payable | 12.14M | 10.93M | 6.51M | 5.53M | 5.79M |
| Accumulated other comprehensive income | 0.02M | 0.06M | 0.01M | -0.11M | -0.03M |
| Common stock total equity | - | - | - | 0.06M | 0.06M |
| Retained earnings total equity | - | - | - | -577.10M | -467.32M |
| Non currrent assets other | 5.16M | 0.77M | 2.04M | 2.96M | 1.53M |
| Non current assets total | 14.43M | 9.58M | 9.12M | 6.71M | 5.36M |
| Capital lease obligations | 6.12M | 1.65M | 0.84M | 1.59M | 0.40M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | 61.85M | -20.61M | 33.50M | 1.31M | 4.82M |
| Change to liabilities | - | - | - | 0.89M | -0.56M |
| Total cashflows from investing activities | 61.56M | -20.61M | -0.95M | 1.06M | 4.07M |
| Net borrowings | -1.85M | 24.49M | 0.00M | 95.78M | - |
| Total cash from financing activities | 39.92M | 194.62M | 116.93M | 97.13M | 72.32M |
| Change to operating activities | - | - | - | - | -7.69M |
| Net income | -153.49M | -126.87M | -102.24M | -109.78M | -110.82M |
| Change in cash | -60.97M | 77.24M | 39.60M | 10.63M | -8.50M |
| Begin period cash flow | 173.06M | 95.82M | 56.22M | 45.59M | 54.09M |
| End period cash flow | 112.09M | 173.06M | 95.82M | 56.22M | 45.59M |
| Total cash from operating activities | -162.44M | -96.77M | -76.38M | -87.56M | -84.89M |
| Issuance of capital stock | 39.80M | 151.17M | 67.36M | - | 0.00M |
| Depreciation | 2.41M | 1.19M | 1.71M | 1.82M | 1.77M |
| Change to inventory | -7.24M | -3.55M | -1.35M | -0.36M | -2.87M |
| Change to account receivables | -12.78M | -4.86M | -2.74M | -0.99M | -4.67M |
| Sale purchase of stock | - | - | - | 1.35M | -0.08M |
| Other cashflows from financing activities | 39.92M | 18.96M | 49.57M | 97.13M | 72.32M |
| Change to netincome | - | - | - | 11.45M | 23.11M |
| Capital expenditures | 0.29M | 0.29M | 0.19M | 0.25M | 0.75M |
| Change receivables | - | - | - | -0.99M | -4.67M |
| Cash flows other operating | - | - | - | 9.06M | 9.61M |
| Cash and cash equivalents changes | - | - | - | 10.63M | -8.50M |
| Change in working capital | -27.91M | 4.93M | 3.34M | -6.31M | -13.11M |
| Stock based compensation | 11.96M | 13.11M | 9.34M | 10.58M | 23.11M |
| Other non cash items | 4.59M | 10.88M | 11.48M | 16.13M | -1.18M |
| Free cash flow | -162.73M | -97.06M | -76.57M | -87.81M | -85.64M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| URGN UroGen Pharma Ltd |
-0.98 3.81% |
24.75 | - | 37.17 | 11.04 | 19.27 | 11.43 | -2.63 |
| NVO Novo Nordisk A/S |
0.01 0.02% |
40.31 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
4.59 0.85% |
547.09 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
1.45 0.16% |
904.35 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
UroGen Pharma Ltd., a biotechnology company, engages in the development and commercialization of solutions for urothelial and specialty cancers. It offers RTGel, a novel proprietary polymeric biocompatible, reverse thermal gelation hydrogel technology; Mitomycin a generic drug used off-label as an adjuvant chemotherapy for the treatment of low-grade NMIBC after trans-urethral resection of bladder tumor; Zusduri, a sustained-release formulation of mitomycin for the treatment of non-muscle invasive bladder cancer (NMIBC); and Jelmyto for pyelocalyceal solutions. The company's lead product candidates are UGN-103, which is in phase 3 of clinical trial for intravesical solution; and UGN-104 that is in phase 3 of clinical trial for pyelocalyceal solution designed for the treatment of several forms of non-muscle invasive urothelial cancer that include low-grade upper tract urothelial cancer and low-grade intermediate risk NMIBC. It is also developing UGN-301, UGN-301+UGN 201, and UGN-301+gemcitabine that are in phase 1 of clinical trial for the treatment of high-grade NMIBC. The company has license agreement with Agenus Inc. to develop, make, use, sell, import, and commercialize products of Agenus for the treatment of cancers of the urinary tract via intravesical delivery; and licensing and supply agreement with medac Gesellschaft für klinische Spezialpräparate m.b.H. to develop UGN-103 and UGN-104. UroGen Pharma Ltd. was incorporated in 2004 and is headquartered in Princeton, New Jersey.
400 Alexander Park Drive, Princeton, NJ, United States, 08540
646 768 9780
300
| Name | Title | Year Born |
|---|---|---|
| Ms. Elizabeth A. Barrett | Pres, CEO & Director | 1962 |
| Mr. Jason Drew Smith | Gen. Counsel, Chief Compliance Officer & Corp. Sec. | 1972 |
| Dr. Mark P. Schoenberg M.D. | Chief Medical Officer | 1958 |
| Mr. Dong Kim | Chief Financial Officer | 1977 |
| Vincent I. Perrone | Sr. Director of Investor Relations | NA |
| Eric Van Zanten | Sr. Director of Communications | NA |
| Dr. Sari Prutchi-Sagiv Ph.D. | Marketing Director | NA |
| Dr. Marina Konorty | Exec. VP of R&D and Technical Operations | NA |
| Mr. Jeffrey Bova M.B.A. | Chief Commercial Officer | NA |
| Mr. James Ottinger R.ph. | Exec. VP of Regulatory Affairs & Quality | NA |
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