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Xeris Biopharma Holdings, Inc., a biopharmaceutical company, engages in developing and commercializing therapies in Illinois. The company offers Gvoke, a ready-to-use liquid-stable glucagon for the treatment of severe hypoglycemia pediatric and adult patients; Keveyis, a therapy for the treatment of hyperkalemic, hypokalemic, and related variants of primary periodic paralysis; and Recorlev, a cortisol synthesis inhibitor proved for the treatment of endogenous hypercortisolemia in adult patients with Cushing's syndrome. It is also developing XP-8121, a once-weekly subcutaneous injection of levothyroxine that is in phase I clinical trial for the treatment of hypothyroidism; and non-aqueous XeriSol and XeriJect technologies for various therapies. The company was incorporated in 2005 and is headquartered in Chicago, Illinois.
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Xeris Pharmaceuticals develops and commercializes ready-to-use liquid injectable drugs and markets Gvoke, an FDA-approved liquid glucagon for severe hypoglycemia. Its formulation platform may improve drug stability and ease of administration, supporting expansion into diabetes and acute-use markets. Investors may find appeal in recurring product revenue and platform-driven pipeline opportunities.
Major risks include commercialization and reimbursement execution, competition from alternative glucagon products and delivery technologies, regulatory or clinical setbacks, and potential need for additional financing.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Income before tax | -96.08M | -122.72M | -91.25M | -126.04M | -60.08M |
| Net income | -94.66M | -122.72M | -91.14M | -125.58M | -60.08M |
| Selling general administrative | 137.75M | 125.72M | 73.73M | 63.06M | 21.11M |
| Gross profit | 87.61M | 36.27M | 10.83M | 1.12M | 2.42M |
| Reconciled depreciation | 12.67M | 1.88M | 1.47M | 1.08M | 0.32M |
| Ebit | -81.94M | -115.16M | -83.55M | -122.38M | -58.05M |
| Ebitda | -71.10M | -114.61M | -80.58M | -119.57M | -57.73M |
| Depreciation and amortization | 10.84M | 0.55M | 2.96M | 2.81M | 0.32M |
| Non operating income net other | - | - | -7.70M | -3.66M | - |
| Operating income | -81.94M | -115.16M | -83.55M | -122.38M | -59.34M |
| Other operating expenses | 192.19M | 164.75M | 103.70M | 125.10M | 61.81M |
| Interest expense | 15.32M | 7.18M | 10.66M | 7.16M | 2.54M |
| Tax provision | -1.42M | 0.00M | -0.11M | -0.46M | - |
| Interest income | 2.58M | 0.31M | 2.96M | 2.81M | 1.61M |
| Net interest income | -12.75M | -6.87M | -7.70M | -4.35M | -0.93M |
| Income tax expense | -1.42M | -0.11M | -0.11M | -0.46M | 1.81M |
| Total revenue | 110.25M | 49.59M | 20.16M | 2.72M | 2.46M |
| Total operating expenses | 169.55M | 151.43M | 94.37M | 123.50M | 61.77M |
| Cost of revenue | 22.63M | 13.32M | 9.33M | 1.60M | 0.04M |
| Total other income expense net | -14.14M | -7.57M | -7.70M | -3.66M | 0.20M |
| Net income from continuing ops | -94.66M | -122.72M | -91.14M | -125.58M | -60.08M |
| Net income applicable to common shares | -94.66M | -122.72M | -91.14M | -125.58M | -60.08M |
| Breakdown | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Total assets | 322.60M | 344.52M | 304.36M | 159.15M | 108.99M |
| Intangible assets | 109.76M | 3.99M | 131.45M | - | - |
| Other current assets | 5.78M | 9.29M | 4.59M | 3.20M | 4.12M |
| Total liab | 329.38M | 299.33M | 209.13M | 125.39M | 94.55M |
| Total stockholder equity | -6.78M | 45.19M | 95.23M | 33.76M | 14.44M |
| Deferred long term liab | - | - | - | 6.63M | 0.40M |
| Other current liab | 80.13M | 2.66M | 70.12M | 25.09M | 21.73M |
| Common stock | 0.01M | 0.01M | 0.01M | 0.01M | 0.00M |
| Capital stock | 0.01M | 0.01M | 0.01M | 0.01M | 0.00M |
| Retained earnings | -617.02M | -554.77M | -460.11M | -337.38M | -246.25M |
| Other liab | - | 29.24M | 42.02M | 10.16M | 8.91M |
| Good will | 22.86M | 120.61M | 22.86M | - | - |
| Other assets | - | 4.73M | 0.83M | 0.23M | 0.42M |
| Cash | 67.45M | 121.97M | 67.27M | 37.60M | 19.52M |
| Total current liabilities | 95.19M | 73.62M | 79.04M | 28.21M | 27.34M |
| Current deferred revenue | - | 64.78M | - | - | - |
| Net debt | 161.74M | 76.09M | 20.80M | 49.42M | 38.79M |
| Short term debt | 3.50M | 1.58M | 1.58M | - | - |
| Short long term debt total | 229.19M | 198.06M | 88.07M | 87.02M | 58.30M |
| Other stockholder equity | 610.25M | 599.97M | 555.36M | 371.13M | 260.63M |
| Property plant equipment | - | 9.51M | 6.63M | 6.71M | 7.85M |
| Total current assets | 156.26M | 186.82M | 142.60M | 152.21M | 87.48M |
| Long term investments | - | - | - | 0.00M | 13.23M |
| Net tangible assets | - | -98.28M | -59.08M | 33.76M | 14.44M |
| Short term investments | 5.00M | 0.00M | 35.16M | 96.19M | 56.03M |
| Net receivables | 39.20M | 30.83M | 17.46M | 6.88M | 5.64M |
| Long term debt | 190.93M | 187.07M | 88.07M | 87.02M | 58.30M |
| Inventory | 38.84M | 24.73M | 18.12M | 8.35M | 2.18M |
| Accounts payable | 11.56M | 4.61M | 8.92M | 3.12M | 5.60M |
| Accumulated other comprehensive income | -0.03M | -0.02M | -0.03M | 0.01M | 0.04M |
| Common stock total equity | - | - | - | 0.01M | 0.00M |
| Retained earnings total equity | - | - | - | -337.40M | -246.20M |
| Non currrent assets other | 4.54M | 4.73M | 0.83M | -13.00M | 0.42M |
| Non current assets total | 166.34M | 157.70M | 161.76M | 6.94M | 21.50M |
| Capital lease obligations | 38.26M | 10.98M | - | - | - |
| Long term debt total | - | - | - | 87.02M | 58.30M |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Investments | 34.46M | 60.58M | -101.77M | -102.47M | -68.85M |
| Change to liabilities | -4.32M | 5.53M | -2.49M | 4.74M | -1.11M |
| Total cashflows from investing activities | 34.46M | 97.96M | -27.41M | -2.38M | -68.26M |
| Net borrowings | 102.72M | 102.72M | 94.84M | 60.00M | 35.00M |
| Total cash from financing activities | 127.47M | 27.25M | 126.06M | 80.53M | 128.21M |
| Change to operating activities | -9.99M | 19.98M | 7.01M | 13.91M | 2.72M |
| Net income | -94.66M | -122.72M | -91.14M | -125.58M | -60.08M |
| Change in cash | 59.04M | 29.67M | 18.08M | -26.20M | 3.67M |
| Begin period cash flow | 67.27M | 37.60M | 19.52M | 45.72M | 42.05M |
| End period cash flow | 126.31M | 67.27M | 37.60M | 19.52M | 45.72M |
| Total cash from operating activities | -102.89M | -95.53M | -80.56M | -104.35M | -56.28M |
| Issuance of capital stock | 30.00M | 27.00M | 65.89M | 61.69M | 102.76M |
| Depreciation | 12.67M | 1.88M | 1.47M | 1.08M | 0.32M |
| Other cashflows from investing activities | - | - | - | -1.28M | -66.75M |
| Dividends paid | -147.05M | -25.09M | -95.64M | 60.68M | - |
| Change to inventory | -7.46M | -7.42M | -5.14M | -2.18M | 4.04M |
| Change to account receivables | -13.37M | -6.24M | -2.18M | -3.06M | -1.67M |
| Sale purchase of stock | -0.47M | -0.53M | -0.06M | -4.46M | 98.33M |
| Other cashflows from financing activities | 288.49M | 50.96M | 180.97M | 118.99M | 29.89M |
| Change to netincome | 12.69M | 12.50M | 8.27M | 6.48M | 1.73M |
| Capital expenditures | 0.52M | 1.08M | 0.38M | 1.11M | 1.51M |
| Change receivables | - | - | -2.18M | -4.69M | -1.67M |
| Cash flows other operating | - | - | 0.93M | -0.96M | -1.59M |
| Exchange rate changes | - | - | -0.02M | 0.00M | - |
| Cash and cash equivalents changes | - | - | 18.08M | -26.20M | 3.67M |
| Change in working capital | -35.15M | 11.85M | -2.80M | 11.78M | 1.61M |
| Stock based compensation | 12.16M | 11.38M | 8.27M | 6.48M | 1.73M |
| Other non cash items | 3.52M | 0.96M | 3.10M | 0.95M | 0.56M |
| Free cash flow | -103.42M | -96.62M | -80.94M | -105.45M | -57.79M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| XERS Xeris Pharmaceuticals Inc |
2.12 16.21% |
15.20 | - | - | 1.64 | 3.86 | 2.60 | -17.97 |
| NVO Novo Nordisk A/S |
0.47 1.18% |
40.78 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
4.59 0.85% |
547.09 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
1.45 0.16% |
904.35 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Xeris Biopharma Holdings, Inc., a biopharmaceutical company, engages in developing and commercializing therapies in Illinois. The company offers Gvoke, a ready-to-use liquid-stable glucagon for the treatment of severe hypoglycemia pediatric and adult patients; Keveyis, a therapy for the treatment of hyperkalemic, hypokalemic, and related variants of primary periodic paralysis; and Recorlev, a cortisol synthesis inhibitor proved for the treatment of endogenous hypercortisolemia in adult patients with Cushing's syndrome. It is also developing XP-8121, a once-weekly subcutaneous injection of levothyroxine that is in phase I clinical trial for the treatment of hypothyroidism; and non-aqueous XeriSol and XeriJect technologies for various therapies. The company was incorporated in 2005 and is headquartered in Chicago, Illinois.
180 North LaSalle Street, Chicago, IL, United States, 60601
844 445 5704
377
| Name | Title | Year Born |
|---|---|---|
| Mr. Paul R. Edick | Chairman & CEO | 1956 |
| Mr. John P. Shannon | Pres & COO | 1962 |
| Ms. Beth P. Hecht J.D. | Chief Legal Officer & Corp. Sec. | 1964 |
| Dr. Steven J. Prestrelski MBA, Ph.D. | Co-Founder & Chief Scientific Officer | 1964 |
| Mr. Steven M. Pieper | Chief Financial Officer | 1977 |
| Ms. Allison Wey | Sr. VP of Investor Relations & Corp. Communications | NA |
| Dr. Kenneth E. Johnson Pharm. D., Pharm.D. | Sr. VP of Global Devel. & Medical Affairs | 1963 |
| Mr. Kevin McCulloch | Chief Commercial Officer | NA |
| Mr. John P. Shannon | President & COO | 1962 |
| Ms. Beth P. Hecht J.D. | Chief Legal Officer & Corporate Secretary | 1964 |
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