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COSCIENS Biopharma Inc., a life science company, develops and commercializes products for the cosmeceutical, nutraceutical and pharmaceutical markets in the United States, Germany, the United Kingdom, and internationally. It operates through Active Ingredient and Pharmaceutical segments. The company offers active ingredients comprising oat beta glucan, a functional ingredient that supports overall health and wellness; oat powder and peptides; oat oil which is extracted from whole oat kernels by a gentle process that retains all the important biologically active components; and avenanthramides, a natural-based ingredients used to inflammation-based diseases for the cosmeceutical and pharmaceutical industries. It also provides Macrilen/Ghryvelin (macimorelin), an orally active peptidomimetic small molecule that stimulates the secretion of growth hormone from the pituitary gland. The company sells its products through its distribution network. It has license agreements with Pharmanovia, Davimed GmbH, and NK MEDITECH Ltd, as well as Agriculture Canada, Canadian Government, and University of Alberta. The company was formerly known as Aeterna Zentaris Inc. and changed its name to COSCIENS Biopharma Inc. in August 2024. COSCIENS Biopharma Inc. was incorporated in 1990 and is based in Toronto, Canada.
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COSCIENS Biopharma Inc. is a Canadian-listed biopharmaceutical company (CSCI.TO) with limited publicly available disclosure about its programs and operations. Long-term growth may depend on advancement of its development pipeline, licensing or partnership deals and successful regulatory milestones, which could support value creation for investors seeking exposure to early-stage biotech.
Key investment risks include high clinical and regulatory uncertainty, probable need for additional financing and low liquidity that could magnify downside for shareholders.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -10.35M | -15.22M | -4.45M | 4.26M | 2.59M |
| Net income | -10.36M | -15.31M | -3.55M | 3.24M | 2.64M |
| Selling general administrative | 10.06M | 10.45M | 5.62M | 2.75M | 2.58M |
| Gross profit | 2.65M | 4.73M | 2.98M | 8.12M | 8.21M |
| Reconciled depreciation | 1.19M | - | 1.47M | 1.41M | 1.48M |
| Operating income | -10.37M | -18.28M | -4.72M | 4.05M | 2.59M |
| Interest expense | 0.17M | - | 0.10M | 0.10M | 0.12M |
| Tax provision | 0.01M | 0.08M | -0.90M | 1.02M | -0.05M |
| Interest income | 0.28M | 0.36M | 0.33M | 0.07M | - |
| Net interest income | 0.12M | - | 0.19M | -0.07M | -0.16M |
| Total revenue | 7.50M | 9.59M | 7.26M | 13.88M | 13.49M |
| Total operating expenses | 17.86M | 27.87M | 11.98M | 9.83M | 10.90M |
| Cost of revenue | 4.85M | 4.86M | 4.28M | 5.76M | 5.28M |
| Total other income expense net | -0.10M | - | 0.07M | 0.27M | 0.16M |
| Net income from continuing ops | -10.36M | - | -3.55M | 3.24M | 2.64M |
| Net income applicable to common shares | - | -15.31M | - | - | - |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 21.43M | 35.07M | 23.70M | 27.80M | 24.35M |
| Intangible assets | - | 0.00M | 0.01M | 0.01M | 0.01M |
| Other current assets | 0.18M | 0.21M | - | - | - |
| Total liab | 17.59M | 21.91M | 2.71M | 4.01M | 2.61M |
| Total stockholder equity | 3.84M | 13.16M | 21.00M | 23.79M | 21.74M |
| Other current liab | 1.12M | - | - | - | - |
| Common stock | - | 22.49M | - | - | - |
| Capital stock | 22.62M | - | 12.61M | 12.30M | 12.99M |
| Retained earnings | -20.51M | -12.11M | 4.65M | 8.02M | 5.08M |
| Other assets | - | 0.12M | - | - | - |
| Cash | 7.31M | 16.39M | 6.67M | 10.18M | 6.10M |
| Total current liabilities | 3.61M | 7.22M | 1.31M | 1.55M | 0.76M |
| Short term debt | - | 0.00M | - | - | - |
| Other stockholder equity | - | -1.48M | - | - | - |
| Property plant equipment | - | 10.97M | - | - | - |
| Total current assets | 11.50M | 23.98M | 11.19M | 15.17M | 9.73M |
| Net receivables | 1.08M | 1.88M | 0.13M | 2.08M | 1.64M |
| Inventory | 1.31M | 2.69M | 4.00M | 2.77M | 1.82M |
| Accounts payable | 0.74M | - | - | - | - |
| Non currrent assets other | 0.12M | - | 0.01M | - | - |
| Non current assets total | 9.93M | - | 12.51M | 12.63M | 14.62M |
| Capital lease obligations | 2.15M | - | 1.69M | 1.93M | 2.08M |
| Long term debt total | - | 2.04M | - | - | - |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | - | - | -0.74M | -0.29M | -0.62M |
| Total cashflows from investing activities | - | 25.08M | - | - | - |
| Net borrowings | -0.36M | - | - | - | - |
| Total cash from financing activities | -0.41M | -0.59M | -0.27M | -0.16M | -0.24M |
| Net income | -10.36M | -15.31M | -3.55M | -22.73M | -8.37M |
| Change in cash | -9.09M | 9.71M | -3.74M | 4.44M | 1.89M |
| Begin period cash flow | 16.39M | - | 10.41M | 5.73M | 4.21M |
| End period cash flow | 7.31M | - | 6.67M | 10.18M | 6.10M |
| Total cash from operating activities | -8.47M | -14.57M | -2.73M | 4.89M | 2.75M |
| Depreciation | 1.19M | 1.61M | 1.47M | 1.41M | 1.48M |
| Other cashflows from investing activities | - | 26.24M | - | - | - |
| Change to inventory | - | - | -1.17M | -1.06M | -0.87M |
| Change to account receivables | - | - | 2.00M | -0.54M | -0.06M |
| Sale purchase of stock | - | -0.17M | - | - | - |
| Capital expenditures | 0.71M | 1.16M | 0.74M | 0.29M | 0.56M |
| Change in working capital | 0.29M | -1.77M | 0.06M | -0.84M | -1.16M |
| Stock based compensation | -0.01M | - | 0.20M | 0.07M | 0.01M |
| Other non cash items | 0.05M | - | 0.10M | 0.10M | 0.12M |
| Free cash flow | -9.18M | - | -3.47M | 4.60M | 2.20M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(CAD) |
Price
(CAD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| CSCI COSCIENS Biopharma Inc. |
- -% |
8.50 | - | - | 1.16 | 1.66 | 0.16 | 4.57 |
| EPRX Eupraxia Pharmaceuticals Inc |
-0.17 1.76% |
9.48 | - | - | - | 8.45 | - | -3.88 |
| FRX Fennec Pharmaceuticals Inc |
0.20 1.35% |
14.99 | - | 21.01 | 6.95 | 6.35 | 4.25 | 20.27 |
| MSCL Satellos Bioscience Inc. |
- -% |
9.00 | - | - | - | 5.85 | - | 6.47 |
| HBP Helix BioPharma Corp. |
-0.10 9.80% |
0.92 | - | 3.87 | 4263.36 | 9.74 | 4422.35 | -6.36 |
COSCIENS Biopharma Inc., a life science company, develops and commercializes products for the cosmeceutical, nutraceutical and pharmaceutical markets in the United States, Germany, the United Kingdom, and internationally. It operates through Active Ingredient and Pharmaceutical segments. The company offers active ingredients comprising oat beta glucan, a functional ingredient that supports overall health and wellness; oat powder and peptides; oat oil which is extracted from whole oat kernels by a gentle process that retains all the important biologically active components; and avenanthramides, a natural-based ingredients used to inflammation-based diseases for the cosmeceutical and pharmaceutical industries. It also provides Macrilen/Ghryvelin (macimorelin), an orally active peptidomimetic small molecule that stimulates the secretion of growth hormone from the pituitary gland. The company sells its products through its distribution network. It has license agreements with Pharmanovia, Davimed GmbH, and NK MEDITECH Ltd, as well as Agriculture Canada, Canadian Government, and University of Alberta. The company was formerly known as Aeterna Zentaris Inc. and changed its name to COSCIENS Biopharma Inc. in August 2024. COSCIENS Biopharma Inc. was incorporated in 1990 and is based in Toronto, Canada.
| Name | Title | Year Born |
|---|---|---|
| Mr. Gilles R. Gagnon ICD.D, M.B.A., M.Sc. | President, CEO & Director | 1954 |
| Mr. Giuliano La Fratta | Senior VP of Finance & CFO | NA |
| Dr. Michael Teifel Ph.D. | Senior VP of Non-Clinical Development & Chief Scientific Officer | NA |
| Dr. Nicola Ammer M.D. | Chief Medical Officer & Senior VP of Clinical Development | NA |
| Dr. Matthias Gerlach | Senior Vice President Manufacturing and Supply Chain & Head of Production | NA |
| Mr. Michel Regnier P. Eng. | Senior VP of Technical operations, MD of Ceapro Inc. & CTO | NA |
| Dr. Michael Teifel Ph.D. | Senior Vice President of GmbH & Chief Scientific Officer | NA |
| Ms. Anna Elizabeth Biehn | Chief Executive Officer | NA |
| Mr. Peter Harry Puccetti CFA | Interim CEO & Independent Chairman | NA |
| Dr. Klaus Paulini Ph.D. | President & CEO | NA |
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