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PepGen Inc., a clinical-stage biotechnology company, focuses on the development of oligonucleotide therapeutics for use in the treatment of severe neuromuscular and neurologic diseases. Its lead product candidate is PGN-EDO51, an EDO peptide that is in Phase 2 clinical trial to treat Duchenne muscular dystrophy (DMD) patients. The company is also developing PGN-EDODM1, an EDO peptide-conjugated PMO, which is in Phase 1 clinical trial for the treatment of myotonic dystrophy type 1, as well as EDO therapeutic candidates, such as PGN-EDO53, PGN-EDO45, and PGN-EDO44 for the treatment of DMD. PepGen Inc. was founded in 2018 and is based in Boston, Massachusetts.
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PepGen Ltd is a clinical-stage biotechnology company developing oligonucleotide-based therapeutics using a proprietary delivery chemistry to address neuromuscular and central nervous system genetic diseases. Its long-term growth drivers include clinical progress of lead programs, platform licensing or partnerships and demand for treatments in rare genetic disorders, which may benefit shareholders if trials demonstrate safety and efficacy.
The principal risks are program-level clinical and regulatory failure, limited operating history and the need for additional financing to advance development.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Income before tax | -65.40M | -27.28M | -1.89M | - |
| Net income | -69.10M | -27.28M | -1.88M | - |
| Selling general administrative | 14.22M | 8.11M | 0.85M | - |
| Reconciled depreciation | 0.49M | 0.18M | 0.11M | - |
| Ebit | -68.79M | -27.11M | -1.88M | -1.35M |
| Ebitda | -68.30M | -26.93M | -1.77M | - |
| Depreciation and amortization | 0.49M | 0.18M | 0.11M | - |
| Non operating income net other | 2.90M | - | - | - |
| Operating income | -68.30M | -27.11M | -1.88M | - |
| Other operating expenses | 68.30M | 27.11M | 1.88M | - |
| Interest expense | 3.40M | 0.17M | 0.01M | 0.00M |
| Tax provision | 3.71M | - | - | - |
| Interest income | 2.79M | 0.00M | 0.01M | - |
| Net interest income | 2.79M | 0.00M | 0.01M | - |
| Income tax expense | 3.71M | 0.17M | -0.01M | - |
| Total revenue | 0.00M | 0.00M | 0.00M | - |
| Total operating expenses | 68.30M | 27.11M | 1.88M | - |
| Total other income expense net | 2.90M | -0.17M | -0.01M | - |
| Net income from continuing ops | -69.10M | -27.28M | -1.89M | - |
| Net income applicable to common shares | -69.10M | -27.28M | -4.08M | -1.35M |
| Breakdown | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Total assets | 143.05M | 217.44M | 143.64M | 10.64M | - |
| Other current assets | 2.27M | 4.27M | 2.35M | 0.13M | - |
| Total liab | 34.63M | 37.81M | 10.55M | 0.87M | - |
| Total stockholder equity | 108.42M | 179.63M | 133.09M | 9.77M | - |
| Deferred long term liab | - | - | 1.50M | - | - |
| Other current liab | 13.52M | 11.91M | 7.08M | 0.12M | - |
| Common stock | 0.00M | 0.00M | - | - | - |
| Capital stock | 0.00M | 0.00M | 165.18M | 16.13M | - |
| Retained earnings | -181.48M | -102.86M | -33.75M | -6.47M | -2.39M |
| Other assets | 0.00M | 1.47M | 3.02M | - | - |
| Cash | 80.77M | 181.75M | 132.90M | 9.78M | - |
| Total current liabilities | 17.53M | 18.83M | 10.32M | 0.84M | 0.33M |
| Current deferred revenue | 0.00M | - | - | - | - |
| Net debt | -60.67M | -157.22M | -132.90M | -9.78M | - |
| Short term debt | 3.00M | 5.55M | - | - | - |
| Short long term debt total | 20.10M | 24.53M | - | - | - |
| Other stockholder equity | 146.81M | 65.13M | 1.65M | 0.12M | -0.01M |
| Property plant equipment | - | 3.33M | 0.64M | 0.32M | 0.42M |
| Total current assets | 112.68M | 186.08M | 139.99M | 10.32M | 3.77M |
| Net tangible assets | - | 179.63M | -32.08M | -6.36M | 3.87M |
| Short term investments | 29.63M | - | - | - | - |
| Net receivables | - | 0.06M | 4.74M | 0.41M | 0.23M |
| Accounts payable | 1.00M | 1.36M | 3.24M | 0.72M | 0.14M |
| Accumulated other comprehensive income | 0.03M | -0.08M | 0.02M | -0.01M | - |
| Common stock total equity | - | 0.00M | - | - | - |
| Retained earnings total equity | - | -102.86M | - | - | - |
| Non currrent assets other | 0.44M | 1.47M | 3.02M | - | - |
| Non current assets total | 30.37M | 31.36M | 3.65M | 0.32M | - |
| Capital lease obligations | 20.10M | 24.53M | - | - | - |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Investments | -3.75M | -0.50M | -0.01M | - |
| Change to liabilities | 4.12M | 2.51M | 0.33M | 0.06M |
| Total cashflows from investing activities | -3.75M | -0.50M | -0.01M | -0.03M |
| Total cash from financing activities | 112.19M | 147.66M | 7.95M | 2.79M |
| Change to operating activities | 1.73M | 4.61M | -0.15M | 0.41M |
| Net income | -69.10M | -27.28M | -1.89M | -1.35M |
| Change in cash | 48.86M | 124.59M | 6.29M | 1.94M |
| Begin period cash flow | 134.37M | 9.78M | 3.49M | - |
| End period cash flow | 183.22M | 134.37M | 9.78M | 3.49M |
| Total cash from operating activities | -59.27M | -22.60M | -1.65M | -0.89M |
| Issuance of capital stock | 114.27M | 149.04M | 7.96M | - |
| Depreciation | 0.49M | 0.18M | 0.11M | 0.11M |
| Change to account receivables | 4.18M | -4.34M | -0.17M | -0.11M |
| Sale purchase of stock | 114.89M | - | - | - |
| Other cashflows from financing activities | -2.07M | 147.66M | 7.95M | -0.00M |
| Change to netincome | 4.84M | 1.73M | 0.12M | 0.12M |
| Capital expenditures | 3.75M | 0.50M | 0.01M | 0.03M |
| Change receivables | 4.18M | - | - | - |
| Cash flows other operating | -3.80M | - | - | - |
| Cash and cash equivalents changes | 49.17M | - | - | - |
| Change in working capital | 4.51M | 2.77M | 0.01M | - |
| Stock based compensation | 4.76M | 1.53M | 0.12M | - |
| Other non cash items | 0.08M | 0.20M | - | - |
| Free cash flow | -63.02M | -23.10M | -1.66M | - |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|
| PEPG PepGen Ltd |
3.36 140.59% |
5.75 | - | - | - | 3.89 | -3.95 |
| NVO Novo Nordisk A/S |
-0.70 1.70% |
40.67 | 41.58 | 31.15 | 2.13 | 32.99 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-0.79 0.14% |
550.08 | 30.22 | 24.27 | 10.36 | 6.50 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
-6.17 0.67% |
913.79 | 29.07 | 20.12 | 7.57 | 3.82 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 36.06 |
PepGen Inc., a clinical-stage biotechnology company, focuses on the development of oligonucleotide therapeutics for use in the treatment of severe neuromuscular and neurologic diseases. Its lead product candidate is PGN-EDO51, an EDO peptide that is in Phase 2 clinical trial to treat Duchenne muscular dystrophy (DMD) patients. The company is also developing PGN-EDODM1, an EDO peptide-conjugated PMO, which is in Phase 1 clinical trial for the treatment of myotonic dystrophy type 1, as well as EDO therapeutic candidates, such as PGN-EDO53, PGN-EDO45, and PGN-EDO44 for the treatment of DMD. PepGen Inc. was founded in 2018 and is based in Boston, Massachusetts.
| Name | Title | Year Born |
|---|---|---|
| Dr. James G. McArthur Ph.D. | Pres, CEO, Treasurer, Sec. & Director | 1962 |
| Ms. Caroline Godfrey Ph.D. | Founder & Scientific Advisory Board Member | NA |
| Mr. Noel Donnelly M.B.A. | Chief Financial Officer | 1970 |
| Dr. Jaya Goyal Ph.D. | Exec. VP of Research & Preclinical Devel. | 1968 |
| Dr. Michael Gait | Founder & Scientific Advisory Board Member | NA |
| Dr. Sonia Bracegirdle DPHIL | Sr. VP of Strategy & Operations | 1986 |
| Ms. Jennifer Cormier | Sr. VP of Clinical Operations | NA |
| Dr. Michelle L. Mellion M.D. | Sr. VP & Head of Clinical Devel. | 1976 |
| Mr. Niels Svenstrup Ph.D. | Sr. VP of Chemistry, Manufacturing & Control | 1970 |
| Mr. Kyle Breidenstine | VP of Fin. & Controller | NA |
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