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Black Diamond Therapeutics, Inc., a clinical-stage oncology company, focuses on the discovery and development of MasterKey therapies for patients with genetically defined tumors. The company's lead product candidate is silevertinib, a brain-penetrant epidermal growth factor receptor MasterKey inhibitor, which is in Phase 2 clinical trial for the treatment of epidermal growth factor receptor mutant non-small cell lung cancer, as well as Phase 2 clinical trial to treat glioblastoma. It is also developing BDTX-4933, a brain-penetrant RAF MasterKey inhibitor targeting KRAS, NRAS, and BRAF alterations in solid tumors that is in Phase 1 clinical trial. In addition, the company is developing BDTX-4876, a MasterKey inhibitor of oncogenic FGFR2/3 mutations with selectivity versus FGFR1/4, which is in preclinical stage. The company was formerly known as ASET Therapeutics, Inc. and changed its name to Black Diamond Therapeutics, Inc. in January 2018. Black Diamond Therapeutics, Inc. was incorporated in 2014 and is headquartered in Cambridge, Massachusetts.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
Black Diamond Therapeutics is a clinical-stage precision oncology company developing small-molecule therapies targeting tumor-driving genetic alterations using a proprietary discovery platform. Long-term growth drivers include clinical progress, pipeline expansion to additional mutations, and biomarker-directed development. Investors may find the company attractive for its focus on genetically defined tumor subsets and potential to address unmet needs.
Key investment risks are clinical or regulatory failure of lead candidates, high cash burn and likely need for additional financing, and intense competition in targeted oncology.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | 22.37M | -69.68M | -82.44M | -88.92M | -125.60M |
| Net income | 22.37M | -69.68M | -82.44M | -84.52M | -123.20M |
| Selling general administrative | 16.57M | 27.47M | 27.11M | 28.39M | 30.04M |
| Selling and marketing expenses | - | - | 27.08M | - | - |
| Gross profit | 69.67M | -0.34M | -0.44M | - | - |
| Reconciled depreciation | 0.33M | 0.34M | 0.44M | 0.51M | 0.20M |
| Ebit | 19.87M | -78.78M | -86.46M | -92.83M | -126.87M |
| Ebitda | 20.20M | -78.44M | -86.02M | -95.06M | -125.60M |
| Depreciation and amortization | 0.33M | 0.34M | 0.44M | -2.23M | 1.28M |
| Non operating income net other | - | - | - | 1.66M | 1.28M |
| Operating income | 19.87M | -78.78M | -86.46M | -92.83M | -126.87M |
| Other operating expenses | 50.13M | 78.78M | 86.46M | 92.83M | 126.87M |
| Interest expense | - | - | - | -3.91M | 1.28M |
| Interest income | 4.06M | 2.18M | 1.92M | 2.03M | 3.46M |
| Net interest income | 4.06M | 2.18M | 1.92M | 2.03M | 3.46M |
| Income tax expense | - | - | - | -4.40M | -2.39M |
| Total revenue | 70.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 49.80M | 78.78M | 86.02M | 92.83M | 126.87M |
| Cost of revenue | 0.33M | 0.34M | 0.44M | - | - |
| Total other income expense net | 2.50M | 9.11M | 4.02M | 3.91M | 1.28M |
| Net income from continuing ops | 22.37M | -69.68M | -82.44M | -91.17M | -125.60M |
| Net income applicable to common shares | - | - | - | -91.17M | -125.60M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 143.01M | 122.64M | 158.57M | 156.25M | 247.68M |
| Other current assets | 3.79M | 2.60M | 2.63M | 4.90M | 5.92M |
| Total liab | 30.80M | 39.35M | 41.83M | 40.56M | 491.50M |
| Total stockholder equity | 112.21M | 83.28M | 116.74M | -334.99M | -243.82M |
| Other current liab | 15.15M | 13.16M | 14.21M | 10.54M | 19.21M |
| Common stock | 0.01M | 0.01M | 0.01M | 0.01M | 0.01M |
| Capital stock | 0.01M | 0.01M | 0.01M | 0.01M | 0.01M |
| Retained earnings | -464.74M | -487.11M | -417.43M | -334.99M | -243.82M |
| Other assets | - | - | 0.00M | 1.17M | 1.24M |
| Cash | 20.99M | 36.44M | 56.22M | 34.31M | 65.80M |
| Total current liabilities | 15.73M | 20.57M | 19.65M | 15.26M | 23.64M |
| Net debt | -5.92M | -14.25M | -30.92M | -6.17M | -37.34M |
| Short term debt | - | 3.40M | 3.11M | 2.84M | 0.32M |
| Short long term debt total | 15.07M | 22.19M | 25.30M | 28.14M | 28.46M |
| Other stockholder equity | 576.84M | 570.36M | 534.19M | 1.82M | 0.41M |
| Property plant equipment | - | - | - | 2.59M | 30.74M |
| Total current assets | 132.44M | 101.18M | 134.03M | 127.71M | 209.79M |
| Net tangible assets | - | - | - | 115.69M | 195.90M |
| Short term investments | 107.66M | 62.14M | 75.18M | 88.49M | 143.99M |
| Accounts payable | 0.58M | 4.01M | 2.32M | 1.88M | 4.11M |
| Accumulated other comprehensive income | 0.10M | 0.02M | -0.03M | -1.82M | -0.41M |
| Common stock total equity | - | - | - | 0.01M | 0.01M |
| Retained earnings total equity | - | - | - | -334.99M | -243.82M |
| Non currrent assets other | 0.07M | 1.07M | 0.82M | 1.17M | 7.16M |
| Non current assets total | 10.57M | 21.46M | 24.53M | 28.55M | 37.90M |
| Capital lease obligations | 18.78M | 22.19M | 25.30M | 28.14M | 28.46M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | -44.93M | 16.97M | 16.35M | 53.55M | 133.32M |
| Change to liabilities | - | - | - | -8.09M | 1.57M |
| Total cashflows from investing activities | -44.91M | 16.97M | 16.35M | 53.37M | 130.61M |
| Total cash from financing activities | -0.15M | 25.55M | 71.93M | 0.18M | 0.73M |
| Change to operating activities | - | - | - | -7.67M | 5.45M |
| Net income | 22.37M | -69.68M | -82.44M | -91.17M | -125.60M |
| Change in cash | -15.44M | -19.79M | 21.56M | -31.54M | 31.19M |
| Begin period cash flow | 37.26M | 57.04M | 35.48M | 67.02M | 35.83M |
| End period cash flow | 21.82M | 37.26M | 57.04M | 35.48M | 67.02M |
| Total cash from operating activities | 29.61M | -62.30M | -66.72M | -85.08M | -100.15M |
| Issuance of capital stock | 0.00M | 24.49M | 71.85M | - | 0.00M |
| Depreciation | 0.33M | 0.34M | 0.44M | 0.51M | 0.20M |
| Other cashflows from investing activities | 0.07M | 0.09M | 0.10M | 0.01M | - |
| Sale purchase of stock | - | - | - | 0.18M | 0.73M |
| Other cashflows from financing activities | -0.15M | 1.05M | 0.08M | 53.37M | 0.73M |
| Change to netincome | - | - | - | 12.21M | 18.22M |
| Capital expenditures | 0.00M | 0.00M | 0.03M | 0.19M | 2.71M |
| Cash flows other operating | - | - | - | 0.92M | -1.26M |
| Cash and cash equivalents changes | - | - | - | -31.54M | 31.19M |
| Change in working capital | -8.73M | -2.69M | 3.69M | -9.90M | 7.02M |
| Stock based compensation | 6.63M | 10.63M | 9.60M | 12.20M | 14.04M |
| Other non cash items | 9.02M | -0.91M | 2.00M | 3.28M | 2.01M |
| Free cash flow | 29.61M | -62.30M | -66.75M | -85.27M | -102.86M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| BDTX Black Diamond Therapeutics Inc |
-0.07 4.04% |
1.54 | 8.08 | 8.33 | 2.58 | 1.56 | 0.93 | 3.21 |
| NVO Novo Nordisk A/S |
-0.54 1.32% |
40.55 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-2.37 0.43% |
544.66 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
-2.77 0.29% |
956.64 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Black Diamond Therapeutics, Inc., a clinical-stage oncology company, focuses on the discovery and development of MasterKey therapies for patients with genetically defined tumors. The company's lead product candidate is silevertinib, a brain-penetrant epidermal growth factor receptor MasterKey inhibitor, which is in Phase 2 clinical trial for the treatment of epidermal growth factor receptor mutant non-small cell lung cancer, as well as Phase 2 clinical trial to treat glioblastoma. It is also developing BDTX-4933, a brain-penetrant RAF MasterKey inhibitor targeting KRAS, NRAS, and BRAF alterations in solid tumors that is in Phase 1 clinical trial. In addition, the company is developing BDTX-4876, a MasterKey inhibitor of oncogenic FGFR2/3 mutations with selectivity versus FGFR1/4, which is in preclinical stage. The company was formerly known as ASET Therapeutics, Inc. and changed its name to Black Diamond Therapeutics, Inc. in January 2018. Black Diamond Therapeutics, Inc. was incorporated in 2014 and is headquartered in Cambridge, Massachusetts.
245 First Street, Cambridge, MA, United States, 02142
617 252 0848
21
| Name | Title | Year Born |
|---|---|---|
| Dr. David M. Epstein Ph.D. | Co-Founder, Pres, CEO & Director | 1959 |
| Dr. Fang Ni Pharm.D. | CFO, Principal Financial Officer and Chief Bus. Officer | 1987 |
| Mr. Brent Hatzis-Schoch Esq., J.D. | COO & Gen. Counsel | 1965 |
| Dr. Elizabeth Buck Ph.D. | Co-Founder & Chief Scientific Officer | 1975 |
| Ms. Erika Jones | VP of Fin., Corp. Controller & Principal Accounting Officer | 1985 |
| Ms. Elizabeth L. Montgomery | Chief People Officer | 1972 |
| Dr. Christopher D. Roberts Ph.D. | Advisor | 1970 |
| Mr. Tai-An Lin Ph.D. | Sr. VP of Translational Science & Discovery Biology | NA |
| Dr. Sergey Yurasov M.D., Ph.D. | Chief Medical Officer | 1969 |
| Ms. Melanie Morrison | Sr. VP of Devel. Operations | NA |
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