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enVVeno Medical Corporation, a medical device company, focuses on the development of bioprosthetic tissue-based solutions to enhance the standard of care in the treatment of venous disease in the United States. The company's lead product is the VenoValve, a surgical replacement venous valve for the treatment of venous chronic venous insufficiency. Its VenoValve implanted into the femoral vein of the patient in an open surgical procedure via a 5-to-6-inch incision in the upper thigh. The company also develops enVVe, a non-surgical and transcatheter-based replacement venous valve system consisting of the enVVe valve, enVVe delivery system, and delivery system accessories. The company was formerly known as Hancock Jaffe Laboratories, Inc. and changed its name to enVVeno Medical Corporation in October 2021. enVVeno Medical Corporation was incorporated in 1999 and is based in Irvine, California.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
enVVeno Medical Corporation is a clinical-stage medical device company focused on treatments for chronic venous disease; public information on its pipeline and go-to-market plan is limited. Long-term growth drivers include an aging population, rising venous disease prevalence and progress on clinical and regulatory milestones, which may benefit investors seeking medtech exposure.
Key risks include adverse clinical or regulatory outcomes, the need for additional financing before commercialization, uncertain reimbursement and strong competition.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -19.47M | -21.82M | -23.52M | -24.67M | -16.53M |
| Net income | -19.47M | -21.82M | -23.52M | -24.30M | -16.20M |
| Selling general administrative | 10.92M | 11.58M | 12.02M | 15.02M | 11.16M |
| Gross profit | -0.49M | -0.53M | -0.55M | - | - |
| Reconciled depreciation | 0.49M | 0.53M | 0.54M | 0.53M | 0.45M |
| Ebit | -19.47M | -21.82M | -23.52M | -24.93M | -16.89M |
| Ebitda | -18.98M | -21.29M | -22.97M | -24.51M | -16.75M |
| Depreciation and amortization | 0.49M | 0.53M | 0.55M | 0.42M | 0.14M |
| Non operating income net other | - | - | - | 0.10M | - |
| Operating income | -20.90M | -23.83M | -25.24M | -24.93M | -16.89M |
| Other operating expenses | 20.90M | 23.83M | 25.24M | 24.93M | 16.89M |
| Interest expense | - | - | - | 0.26M | 0.02M |
| Interest income | 0.69M | 0.39M | 0.17M | 0.16M | - |
| Net interest income | 0.69M | 0.39M | 0.17M | 0.16M | 0.02M |
| Income tax expense | - | - | - | -0.36M | -0.33M |
| Total revenue | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 20.90M | 23.30M | 24.69M | 24.93M | 16.89M |
| Cost of revenue | 0.49M | 0.53M | 0.55M | - | - |
| Total other income expense net | 1.43M | 2.01M | 1.72M | 0.26M | 0.36M |
| Net income from continuing ops | -19.47M | -21.82M | -24.05M | -24.67M | -16.53M |
| Net income applicable to common shares | - | - | - | -24.67M | -16.53M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 29.56M | 44.95M | 48.63M | 41.66M | 57.70M |
| Other current assets | 0.61M | 0.58M | 0.51M | 0.39M | 0.31M |
| Total liab | 2.43M | 2.79M | 2.44M | 2.93M | 3.29M |
| Total stockholder equity | 27.13M | 42.16M | 46.20M | 38.73M | 54.40M |
| Other current liab | 1.37M | 0.72M | 1.03M | 0.57M | 0.06M |
| Common stock | - | - | - | - | 0.00M |
| Capital stock | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Retained earnings | -171.33M | -151.85M | -130.04M | -106.52M | -81.85M |
| Other assets | - | - | 0.00M | 0.03M | 0.05M |
| Cash | 3.06M | 1.75M | 3.62M | 4.55M | 54.73M |
| Total current liabilities | 2.12M | 2.10M | 1.37M | 1.53M | 1.58M |
| Current deferred revenue | - | - | -0.43M | - | 0.67M |
| Net debt | -2.37M | -0.69M | -2.22M | -2.84M | -52.72M |
| Short term debt | 0.39M | 0.36M | 0.34M | 0.31M | 0.29M |
| Short long term debt total | 0.70M | 1.06M | 1.40M | 1.72M | 2.01M |
| Other stockholder equity | 198.46M | 194.01M | 176.24M | 145.25M | 136.26M |
| Property plant equipment | - | - | - | 0.52M | 2.60M |
| Total current assets | 28.83M | 43.73M | 46.92M | 39.44M | 55.04M |
| Net tangible assets | - | - | - | 38.73M | 54.40M |
| Short term investments | 25.15M | 41.40M | 42.79M | 34.49M | - |
| Accounts payable | 0.36M | 1.01M | 0.43M | 0.65M | 0.56M |
| Retained earnings total equity | - | - | - | -106.52M | - |
| Non currrent assets other | 0.03M | 0.03M | 0.03M | 0.03M | 0.05M |
| Non current assets total | 0.74M | 1.22M | 1.71M | 2.23M | 2.66M |
| Capital lease obligations | 0.70M | 1.06M | 1.40M | 1.72M | 2.01M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | 15.86M | 1.33M | 19.79M | -34.44M | -0.37M |
| Change to liabilities | - | - | - | 0.09M | -0.83M |
| Total cashflows from investing activities | 15.86M | 1.33M | -7.87M | -34.55M | -0.37M |
| Total cash from financing activities | 1.02M | 13.64M | 25.79M | 0.00M | 57.61M |
| Change to operating activities | - | - | - | -0.51M | -0.62M |
| Net income | -19.47M | -21.82M | -23.52M | -24.67M | -16.53M |
| Change in cash | 1.31M | -1.87M | -0.94M | -50.17M | 45.39M |
| Begin period cash flow | 1.75M | 3.62M | 4.55M | 54.73M | 9.33M |
| End period cash flow | 3.06M | 1.75M | 3.62M | 4.55M | 54.73M |
| Total cash from operating activities | -15.57M | -16.84M | -18.86M | -15.62M | -11.85M |
| Issuance of capital stock | 0.78M | 13.59M | 25.79M | 0.00M | 57.36M |
| Depreciation | 0.49M | 0.53M | 0.55M | 0.53M | 0.45M |
| Other cashflows from financing activities | 1.02M | 0.05M | -7.87M | -34.55M | 0.25M |
| Change to netincome | - | - | - | 9.05M | 5.69M |
| Capital expenditures | 0.01M | 0.04M | 0.03M | 0.12M | 0.37M |
| Cash and cash equivalents changes | - | - | - | -50.17M | - |
| Change in working capital | -0.40M | 0.29M | -0.62M | -0.13M | -1.14M |
| Stock based compensation | 3.42M | 4.14M | 5.20M | 8.99M | 6.00M |
| Other non cash items | 0.39M | 0.02M | -0.47M | -0.34M | -0.31M |
| Free cash flow | -15.57M | -16.88M | -18.89M | -15.73M | -12.21M |
Sector: Healthcare Industry: Medical Devices
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| NVNO enVVeno Medical Corp |
-0.02 0.31% |
6.50 | - | - | 216.91 | 0.32 | 274.86 | -0.87 |
| ABT Abbott Laboratories |
-0.71 0.65% |
108.58 | 25.97 | 17.24 | 3.57 | 3.20 | 3.81 | 16.75 |
| MDT Medtronic PLC |
0.28 0.28% |
101.89 | 26.60 | 15.87 | 3.35 | 2.08 | 3.90 | 14.12 |
| SYK Stryker Corporation |
-2.16 0.68% |
316.63 | 29.23 | 16.86 | 4.18 | 4.51 | 4.63 | 17.16 |
| SEMHF Siemens Healthineers AG |
- -% |
47.31 | 39.57 | 21.32 | 3.01 | 3.29 | 2.95 | 16.92 |
enVVeno Medical Corporation, a medical device company, focuses on the development of bioprosthetic tissue-based solutions to enhance the standard of care in the treatment of venous disease in the United States. The company's lead product is the VenoValve, a surgical replacement venous valve for the treatment of venous chronic venous insufficiency. Its VenoValve implanted into the femoral vein of the patient in an open surgical procedure via a 5-to-6-inch incision in the upper thigh. The company also develops enVVe, a non-surgical and transcatheter-based replacement venous valve system consisting of the enVVe valve, enVVe delivery system, and delivery system accessories. The company was formerly known as Hancock Jaffe Laboratories, Inc. and changed its name to enVVeno Medical Corporation in October 2021. enVVeno Medical Corporation was incorporated in 1999 and is based in Irvine, California.
| Name | Title | Year Born |
|---|---|---|
| Mr. Robert A. Berman | CEO & Director | 1963 |
| Mr. Craig Thomas Glynn | CFO, Treasurer & Sec. | 1961 |
| Dr. Marc H. Glickman M.D. | Sr. VP & Chief Medical Officer | 1949 |
| Mr. Warren Hancock | Co-founder | NA |
| Dr. Benedict Broennimann M.D. | Chief Medical Officer of Outside of United States | 1957 |
| Mr. Craig Thomas Glynn | CFO, Treasurer & Secretary | 1961 |
| Dr. Hamed Alavi Ph.D. | Senior VP & Chief Technology Officer | NA |
| Dr. Marc H. Glickman M.D. | Senior VP & Chief Medical Officer | 1949 |
| Mr. Andrew Cormack | Chief Commercial Officer | NA |
| Ms. Jennifer Bright CPA | Chief Financial Officer | 1971 |
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