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Phio Pharmaceuticals Corp. develops immuno-oncology therapeutics in the United States. The company is developing PH-762, an INTASYL compound in Phase 1b dose-escalating clinical trials to reduce the expression of cell death protein 1 (PD-1), a protein that inhibits T cells' ability to kill cancer cells; and PH-762 treated double positive tumor infiltrating lymphocytes, which is in Phase 1 clinical trials to treat advanced melanoma and other advanced solid tumors. It is also developing PH-894, an INTASYL compound in IND enabling studies to silence BRD4, a protein that controls gene expression in both T cells and tumor cells, effecting the immune system and the tumor. The company was formerly known as RXi Pharmaceuticals Corporation and changed its name to Phio Pharmaceuticals Corp. in November 2018. Phio Pharmaceuticals Corp. was incorporated in 2011 and is headquartered in Marlborough, Massachusetts.
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Phio Pharmaceuticals is a clinical-stage biotechnology company developing oligonucleotide-based therapeutics with a proprietary delivery platform aimed at modulating immune response in oncology and other diseases. Long-term growth drivers include clinical trial progress, strategic partnerships or licensing, and potential expansion into additional indications and markets. Investors may find the company attractive for platform upside if development milestones and partnership strategies advance.
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| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Income before tax | -11.48M | -13.29M | -8.79M | -8.91M | -7.36M |
| Net income | -11.30M | -13.21M | -8.79M | -8.84M | -7.36M |
| Selling general administrative | 4.45M | 4.62M | 4.36M | 4.71M | 3.18M |
| Gross profit | - | - | 0.00M | 0.02M | 0.14M |
| Reconciled depreciation | 0.19M | 0.07M | 0.07M | 0.07M | 0.08M |
| Ebit | -11.65M | -13.59M | -8.79M | -9.05M | -7.45M |
| Ebitda | -11.46M | -13.51M | -8.72M | -8.99M | -7.36M |
| Depreciation and amortization | 0.19M | 0.07M | 0.07M | 0.07M | 0.08M |
| Non operating income net other | - | - | - | - | 0.00M |
| Operating income | -11.46M | -13.51M | -8.79M | -8.99M | -7.36M |
| Other operating expenses | 11.46M | 13.51M | 8.79M | 9.01M | 7.50M |
| Interest expense | 0.17M | 0.01M | 0.00M | 0.00M | 0.00M |
| Tax provision | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Net interest income | - | -0.01M | - | - | - |
| Income tax expense | -0.17M | -0.07M | 0.00M | -0.07M | 0.00M |
| Total revenue | 0.00M | 0.00M | 0.00M | 0.02M | 0.14M |
| Total operating expenses | 11.46M | 13.51M | 8.79M | 9.01M | 7.50M |
| Cost of revenue | - | - | - | 4.30M | 4.33M |
| Total other income expense net | -0.02M | 0.22M | -0.00M | 0.08M | 0.00M |
| Net income from continuing ops | -11.48M | -13.29M | -8.79M | -8.91M | -7.36M |
| Net income applicable to common shares | - | -13.29M | -8.79M | -8.91M | -7.36M |
| Breakdown | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Total assets | 9.36M | 12.81M | 25.17M | 15.74M | 8.04M |
| Other current assets | 0.83M | 0.61M | 0.62M | 0.87M | 0.32M |
| Total liab | 1.63M | 1.98M | 3.24M | 2.72M | 2.29M |
| Total stockholder equity | 7.73M | 10.84M | 21.93M | 13.02M | 5.75M |
| Other current liab | 0.94M | 0.89M | 2.66M | 0.10M | 0.03M |
| Common stock | - | - | 0.00M | 0.00M | 0.00M |
| Capital stock | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Retained earnings | -139.21M | -128.38M | -116.90M | -103.61M | -94.82M |
| Other assets | 0.00M | - | 0.03M | 0.00M | 0.02M |
| Cash | 8.49M | 11.78M | 24.06M | 14.24M | 6.93M |
| Total current liabilities | 1.63M | 1.80M | 3.07M | 2.20M | 1.88M |
| Current deferred revenue | - | - | - | 1.25M | 0.94M |
| Net debt | -8.46M | -11.48M | -23.76M | -13.60M | -6.42M |
| Short term debt | 0.04M | 0.14M | 0.12M | 0.12M | 0.11M |
| Short long term debt total | 0.04M | 0.30M | 0.29M | 0.64M | 0.52M |
| Other stockholder equity | 137.57M | 139.22M | 138.83M | 116.63M | 100.57M |
| Property plant equipment | - | - | 0.42M | 0.56M | 0.21M |
| Total current assets | 9.32M | 12.45M | 24.73M | 15.16M | 7.30M |
| Net tangible assets | - | - | 21.93M | 13.02M | 5.75M |
| Long term debt | - | - | - | 0.23M | - |
| Accounts payable | 0.66M | 0.78M | 0.28M | 0.73M | 0.81M |
| Accumulated other comprehensive income | 0.00M | - | - | - | -1.05M |
| Common stock total equity | - | - | - | 0.00M | 0.00M |
| Retained earnings total equity | - | - | - | -103.61M | -94.82M |
| Non currrent assets other | 0.00M | 0.02M | 0.03M | 0.02M | 0.02M |
| Non current assets total | 0.04M | 0.37M | 0.44M | 0.57M | 0.74M |
| Capital lease obligations | 0.04M | 0.17M | 0.29M | 0.41M | 0.52M |
| Long term debt total | - | - | - | 0.23M | - |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Investments | -0.12M | -0.05M | -0.02M | -0.07M | -0.01M |
| Change to liabilities | - | -0.45M | -0.08M | 0.00M | -0.52M |
| Total cashflows from investing activities | - | -0.05M | -0.02M | -0.07M | -0.01M |
| Net borrowings | - | - | 0.20M | -0.01M | -0.01M |
| Total cash from financing activities | -0.03M | 21.72M | 16.13M | 0.77M | 18.82M |
| Change to operating activities | - | 1.44M | -0.25M | -0.47M | -0.56M |
| Net income | -11.48M | -13.29M | -8.79M | -8.91M | -7.36M |
| Change in cash | -12.28M | 9.81M | 7.31M | -7.95M | 11.30M |
| Begin period cash flow | 24.11M | 14.29M | 6.98M | 14.93M | 3.63M |
| End period cash flow | 11.83M | 24.11M | 14.29M | 6.98M | 14.93M |
| Total cash from operating activities | -12.13M | -11.86M | -8.80M | -8.64M | -7.52M |
| Issuance of capital stock | 0.00M | 19.58M | 12.09M | 0.78M | 18.72M |
| Depreciation | 0.19M | 0.07M | 0.07M | 0.07M | 0.08M |
| Dividends paid | - | - | 4.09M | 0.00M | - |
| Sale purchase of stock | - | - | -0.01M | 0.00M | 0.00M |
| Other cashflows from financing activities | 0.00M | 2.15M | 8.17M | -0.00M | 0.10M |
| Change to netincome | - | 0.36M | 0.25M | 0.41M | 0.28M |
| Capital expenditures | 0.12M | 0.05M | 0.02M | 0.07M | 0.01M |
| Cash flows other operating | - | - | -0.55M | -0.21M | -0.00M |
| Cash and cash equivalents changes | - | - | 7.31M | -7.95M | 11.30M |
| Change in working capital | -1.26M | 0.99M | -0.33M | -0.21M | -0.52M |
| Stock based compensation | 0.41M | 0.48M | 0.14M | 0.30M | 0.28M |
| Other non cash items | - | 0.12M | 0.11M | 0.11M | -12.36M |
| Free cash flow | -12.25M | -11.91M | -8.82M | -8.72M | -7.53M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| PHIO Phio Pharmaceuticals Corp |
0.00 0.16% |
0.80 | - | 0.31 | 48.01 | 0.40 | 172.20 | 0.51 |
| NVO Novo Nordisk A/S |
0.01 0.02% |
40.31 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
4.59 0.85% |
547.09 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
1.45 0.16% |
904.35 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Phio Pharmaceuticals Corp. develops immuno-oncology therapeutics in the United States. The company is developing PH-762, an INTASYL compound in Phase 1b dose-escalating clinical trials to reduce the expression of cell death protein 1 (PD-1), a protein that inhibits T cells' ability to kill cancer cells; and PH-762 treated double positive tumor infiltrating lymphocytes, which is in Phase 1 clinical trials to treat advanced melanoma and other advanced solid tumors. It is also developing PH-894, an INTASYL compound in IND enabling studies to silence BRD4, a protein that controls gene expression in both T cells and tumor cells, effecting the immune system and the tumor. The company was formerly known as RXi Pharmaceuticals Corporation and changed its name to Phio Pharmaceuticals Corp. in November 2018. Phio Pharmaceuticals Corp. was incorporated in 2011 and is headquartered in Marlborough, Massachusetts.
| Name | Title | Year Born |
|---|---|---|
| Mr. Robert J. Bitterman | Interim Exec. Chairman | 1951 |
| Dr. Geert Cauwenbergh Dr., Med.Sc., Ph.D. | Interim Principal Exec. & Financial Officer and Director | 1954 |
| Ms. Caitlin Kontulis | VP of Fin. & Admin. and Sec. | 1986 |
| Mr. Robert J. Bitterman | President, CEO & Chairman | 1951 |
| Ms. Caitlin Kontulis | VP of Finance & Administration and Secretary | 1986 |
| Ms. Linda M. Mahoney | Senior Vice President of Development | NA |
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