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Tonix Pharmaceuticals Holding Corp., a biopharmaceutical company, focuses on developing, discovering, commercializing, and licensing therapeutics to treat and prevent human disease and alleviate suffering. It markets Zembrace SymTouch and Tosymra for the treatment of acute migraine with or without aura in adults. Its portfolio focuses on central nervous system disorders, as well as rare disease, immunology, and infectious disease product candidates. The company's priority is to submit a New Drug Application (NDA) to the FDA for TNX-102 SL (cyclobenzaprine HCl sublingual tablet), which has completed two positive Phase 3 studies for the management of fibromyalgia. TNX-102 SL is also being developed to treat fibromyalgia-type Long COVID, a chronic post-acute COVID-19 condition. Its TNX-1300 (cocaine esterase) is a biologic designed to treat cocaine intoxication and has been granted breakthrough therapy designation by the FDA. The company's rare disease development portfolio comprises TNX-2900, an intranasal potentiated oxytocin for the treatment of Prader-Willi syndrome (PWS). Its immunology portfolio includes TNX-1500, which is a biologic to address organ transplant rejection and autoimmune diseases. The company's infectious disease pipeline includes TNX-801, a vaccine in development to prevent smallpox and mpox. TNX-801 also serves as the live virus vaccine platform or recombinant pox vaccine platform for other infectious diseases, including TNX-1800 and TNX-1850, in development as a vaccine to protect against COVID-19. Its infectious disease development portfolio also comprises TNX-3900, and TNX-4200 are orally available CD45 antagonists in preclinical development. The company was founded in 2007 and is headquartered in Chatham, New Jersey.
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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.
Tonix Pharmaceuticals is a clinical-stage biopharmaceutical company developing therapies for central nervous system and immunologic disorders while advancing vaccine candidates. Long-term growth may be driven by clinical trial progress, regulatory approvals, strategic partnerships and successful commercialization of any approved products. Investors may find the company attractive for pipeline exposure to unmet medical needs and potential milestone-driven value creation.
Key investment risks include clinical and regulatory setbacks, limited revenue and cash runway as a development-stage company, potential equity dilution from financing and significant competition in therapeutic areas.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Income before tax | -110.22M | -92.29M | -50.46M | -28.62M | -26.09M |
| Net income | -115.00M | -92.21M | -50.39M | -28.38M | -26.09M |
| Selling general administrative | 30.21M | 23.47M | 14.35M | 10.64M | 8.76M |
| Gross profit | -112.09M | -92.31M | -50.51M | -28.83M | -26.32M |
| Reconciled depreciation | 1.25M | 0.05M | 0.03M | 0.03M | 0.05M |
| Ebit | -113.34M | -92.36M | -50.54M | -28.85M | -26.38M |
| Ebitda | -112.09M | -92.31M | -50.51M | -28.83M | -26.32M |
| Depreciation and amortization | 1.25M | 0.05M | 0.03M | 0.03M | 0.05M |
| Non operating income net other | - | 0.03M | 0.05M | 0.21M | 0.23M |
| Operating income | -112.09M | -92.31M | -50.51M | -28.83M | -26.32M |
| Other operating expenses | 112.09M | 92.31M | 50.51M | 28.83M | 26.32M |
| Interest expense | -7.91M | 0.05M | 0.00M | 0.00M | 0.00M |
| Interest income | 1.87M | 0.03M | 0.05M | 0.21M | 0.23M |
| Net interest income | 1.87M | 0.03M | 0.05M | 0.21M | 0.23M |
| Income tax expense | 4.79M | -0.07M | -0.07M | -0.24M | 0.23M |
| Total revenue | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 112.09M | 92.31M | 50.51M | 28.83M | 26.32M |
| Cost of revenue | 112.09M | 92.31M | 50.51M | 28.83M | 26.32M |
| Total other income expense net | 1.87M | 0.03M | 0.05M | 0.21M | 0.23M |
| Net income from continuing ops | -110.22M | -92.29M | -50.46M | -28.62M | -26.09M |
| Net income applicable to common shares | -116.88M | -92.29M | -52.17M | -31.09M | -29.36M |
| Preferred stock and other adjustments | - | - | 1.26M | 2.47M | 3.27M |
| Breakdown | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Total assets | 154.46M | 225.69M | 240.90M | 98.18M | 14.56M |
| Intangible assets | 9.74M | - | 0.12M | 0.12M | 0.12M |
| Other current assets | 4.08M | 10.55M | 10.39M | 10.92M | 2.70M |
| Total liab | 48.93M | 18.51M | 22.18M | 10.54M | 5.14M |
| Total stockholder equity | 105.53M | 207.18M | 218.72M | 87.65M | 9.42M |
| Other current liab | 9.50M | 6.41M | 5.11M | 2.46M | 1.01M |
| Common stock | 0.06M | 0.08M | 0.50M | 0.21M | 0.01M |
| Capital stock | 0.06M | 0.08M | 0.50M | 0.21M | 0.01M |
| Retained earnings | -600.66M | -470.04M | -359.82M | -267.53M | -217.07M |
| Other liab | - | - | 22.18M | - | 5.14M |
| Good will | 0.96M | - | - | - | - |
| Other assets | - | 0.38M | 51.85M | 1.50M | 0.10M |
| Cash | 24.95M | 120.23M | 178.66M | 77.07M | 11.25M |
| Total current liabilities | 18.88M | 18.18M | 21.72M | 9.82M | 5.13M |
| Current deferred revenue | 2.98M | 3.27M | 2.83M | 2.17M | 0.70M |
| Net debt | -15.13M | -119.47M | -177.70M | -75.76M | -10.89M |
| Short term debt | 2.62M | 0.43M | 0.49M | 0.59M | 0.35M |
| Short long term debt total | 9.81M | 0.76M | 0.96M | 1.31M | 0.36M |
| Other stockholder equity | 706.36M | 677.31M | 578.13M | 355.04M | 226.52M |
| Property plant equipment | - | 94.53M | 51.47M | 9.83M | 0.03M |
| Total current assets | 47.77M | 130.78M | 189.05M | 87.99M | 13.95M |
| Net tangible assets | - | 207.18M | 218.72M | 87.53M | 9.30M |
| Net receivables | 4.59M | 8.04M | 7.73M | 7.63M | 1.01M |
| Long term debt | 6.56M | - | - | - | - |
| Inventory | 14.15M | -8.04M | -7.73M | -7.63M | -1.01M |
| Accounts payable | 3.78M | 8.07M | 13.28M | 4.60M | 3.07M |
| Accumulated other comprehensive income | -0.23M | -0.17M | -0.09M | -0.06M | -0.05M |
| Common stock total equity | - | - | 0.50M | 0.21M | 0.01M |
| Retained earnings total equity | - | - | -359.82M | -267.53M | -217.07M |
| Non currrent assets other | -9.51M | 0.38M | 0.26M | 0.24M | 0.10M |
| Non current assets total | 106.69M | 94.91M | 51.85M | 10.19M | 0.61M |
| Capital lease obligations | 0.90M | 0.76M | 0.96M | 1.31M | 0.36M |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Investments | -48.15M | -35.31M | -8.56M | -0.02M | -0.01M |
| Change to liabilities | -1.04M | 3.53M | 1.53M | 2.12M | 0.52M |
| Total cashflows from investing activities | -48.15M | -35.31M | -8.56M | -0.02M | -0.01M |
| Total cash from financing activities | 87.84M | 212.49M | 123.11M | 12.92M | 23.54M |
| Change to operating activities | 1.04M | 2.25M | -3.89M | -1.21M | 0.33M |
| Net income | -110.22M | -92.29M | -50.46M | -28.62M | -26.09M |
| Change in cash | -58.43M | 101.59M | 65.96M | -13.79M | -0.45M |
| Begin period cash flow | 178.90M | 77.31M | 11.35M | 25.13M | 25.59M |
| End period cash flow | 120.47M | 178.90M | 77.31M | 11.35M | 25.13M |
| Total cash from operating activities | -98.05M | -75.56M | -48.57M | -26.68M | -23.97M |
| Issuance of capital stock | 135.05M | 212.39M | 113.21M | 12.85M | 23.54M |
| Depreciation | 1.25M | 0.05M | 0.03M | 0.03M | 0.05M |
| Dividends paid | -6.66M | - | -0.45M | -2.47M | 3.27M |
| Sale purchase of stock | -47.25M | 3.00M | 1.36M | 12.92M | 23.54M |
| Other cashflows from financing activities | 47.29M | -2.90M | 14.50M | 9.52M | 14.09M |
| Change to netincome | 10.91M | 10.90M | 4.24M | 1.46M | 1.63M |
| Capital expenditures | 48.15M | 35.31M | 8.56M | 0.02M | 0.01M |
| Cash flows other operating | - | 3.51M | -5.45M | -1.67M | -0.08M |
| Exchange rate changes | - | - | - | - | -0.01M |
| Cash and cash equivalents changes | - | 101.62M | 65.97M | -13.78M | -0.45M |
| Change in working capital | -0.00M | 5.78M | -2.37M | 0.45M | 0.44M |
| Stock based compensation | 10.91M | 7.90M | 2.88M | 1.46M | 1.63M |
| Other non cash items | - | 3.00M | 1.36M | 15.04M | 1.35M |
| Free cash flow | -146.20M | -110.86M | -57.13M | -26.70M | -23.98M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| TNXP Tonix Pharmaceuticals Holding Corp |
0.14 3.04% |
4.74 | - | - | 2.00 | 0.15 | 0.04 | -0.00 |
| NVO Novo Nordisk A/S |
0.01 0.02% |
40.31 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
4.59 0.85% |
547.09 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
1.45 0.16% |
904.35 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Tonix Pharmaceuticals Holding Corp., a biopharmaceutical company, focuses on developing, discovering, commercializing, and licensing therapeutics to treat and prevent human disease and alleviate suffering. It markets Zembrace SymTouch and Tosymra for the treatment of acute migraine with or without aura in adults. Its portfolio focuses on central nervous system disorders, as well as rare disease, immunology, and infectious disease product candidates. The company's priority is to submit a New Drug Application (NDA) to the FDA for TNX-102 SL (cyclobenzaprine HCl sublingual tablet), which has completed two positive Phase 3 studies for the management of fibromyalgia. TNX-102 SL is also being developed to treat fibromyalgia-type Long COVID, a chronic post-acute COVID-19 condition. Its TNX-1300 (cocaine esterase) is a biologic designed to treat cocaine intoxication and has been granted breakthrough therapy designation by the FDA. The company's rare disease development portfolio comprises TNX-2900, an intranasal potentiated oxytocin for the treatment of Prader-Willi syndrome (PWS). Its immunology portfolio includes TNX-1500, which is a biologic to address organ transplant rejection and autoimmune diseases. The company's infectious disease pipeline includes TNX-801, a vaccine in development to prevent smallpox and mpox. TNX-801 also serves as the live virus vaccine platform or recombinant pox vaccine platform for other infectious diseases, including TNX-1800 and TNX-1850, in development as a vaccine to protect against COVID-19. Its infectious disease development portfolio also comprises TNX-3900, and TNX-4200 are orally available CD45 antagonists in preclinical development. The company was founded in 2007 and is headquartered in Chatham, New Jersey.
| Name | Title | Year Born |
|---|---|---|
| Dr. Daniel J. Clauw M.D. | Consultant | NA |
| Dr. Seth Lederman M.D. | Co-Founder, Pres, CEO & Chairman | 1958 |
| Mr. Bradley Saenger CPA, CPA | CFO & Treasurer | 1974 |
| Dr. Gregory M. Sullivan M.D. | Chief Medical Officer & Sec. | 1966 |
| Mrs. Jessica Edgar Morris | Chief Operating Officer | NA |
| Dr. Herbert W. Harris M.D., Ph.D. | Exec. VP of Translational Medicine | NA |
| Dr. Bruce L. Daugherty M.B.A., Ph.D. | Exec. VP of Research | 1958 |
| Ms. Siobhan Fogarty B.Sc., M.Sc. | Exec. VP of Product Devel. | NA |
| Dr. Darryl Rideout Ph.D. | Exec. VP of Experimental Chemistry | NA |
| Dr. Sina Bavari Ph.D. | Exec. VP of Infectious Disease R&D | NA |
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