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Wave Life Sciences, Inc., a clinical-stage biotechnology company, focuses on unlocking the potential of ribonucleic acid (RNA) medicines to transform human health. Its RNA medicines platform, PRISM, combines RNA medicine modalities, chemistry innovation, and deep insights in human genetics to deliver scientific breakthroughs that treat rare and common disorders. Its pipeline focuses on obesity (WVE-007), alpha-1 antitrypsin deficiency (AATD) (WVE-006), and PNPLA3 I148M liver disease (WVE-008) programs; and clinical programs for Duchenne muscular dystrophy and Huntington's disease, as well as various preclinical programs utilizing its RNA medicines platform. Wave Life Sciences, Inc. was founded in 2012 and is headquartered in Cambridge, Massachusetts.
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| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -204.38M | -97.01M | -58.19M | -161.14M | -122.45M |
| Net income | -204.38M | -97.01M | -57.51M | -161.82M | -122.25M |
| Selling general administrative | 75.33M | 59.02M | 51.29M | 50.51M | 46.10M |
| Selling and marketing expenses | - | - | 9.21M | - | - |
| Gross profit | 33.88M | 108.30M | 113.31M | 3.65M | 40.96M |
| Reconciled depreciation | 8.85M | 8.66M | 9.21M | 10.11M | 9.84M |
| Ebit | -204.38M | -97.01M | -58.19M | -172.83M | -127.02M |
| Ebitda | -195.53M | -88.34M | -48.98M | -162.72M | -127.05M |
| Depreciation and amortization | 8.85M | 8.66M | 9.21M | 10.11M | -0.03M |
| Non operating income net other | - | - | - | 1.58M | 4.57M |
| Operating income | -215.38M | -110.40M | -68.00M | -162.72M | -127.02M |
| Other operating expenses | 258.11M | 218.71M | 181.30M | 166.37M | 167.98M |
| Interest expense | - | - | - | -1.58M | 14.43M |
| Tax provision | 0.00M | 0.00M | -0.68M | 0.68M | -0.20M |
| Interest income | - | - | - | 1.57M | - |
| Net interest income | - | - | - | 1.57M | - |
| Income tax expense | - | - | -0.68M | 0.68M | -0.20M |
| Total revenue | 42.73M | 108.30M | 113.31M | 3.65M | 40.96M |
| Total operating expenses | 249.26M | 218.71M | 181.30M | 166.37M | 167.98M |
| Cost of revenue | 8.85M | 8.66M | 9.21M | - | - |
| Total other income expense net | 11.01M | 13.39M | 9.81M | 1.58M | 4.57M |
| Net income from continuing ops | -204.38M | -97.01M | -57.51M | -161.82M | -122.25M |
| Net income applicable to common shares | - | - | - | -161.82M | -122.25M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 638.50M | 352.21M | 274.95M | 146.39M | 207.01M |
| Other current assets | 11.47M | 16.89M | 13.94M | 2.11M | 5.42M |
| Total liab | 112.27M | 142.69M | 227.44M | 191.48M | 174.51M |
| Total stockholder equity | 526.23M | 209.51M | 47.50M | -45.09M | 32.50M |
| Other current liab | 26.56M | 21.08M | 16.83M | 17.55M | 14.86M |
| Common stock | 1616.48M | 1175.18M | 935.37M | 802.83M | 749.85M |
| Capital stock | 1616.48M | 1175.18M | 935.37M | 802.83M | 749.85M |
| Retained earnings | -1326.24M | -1121.86M | -1024.85M | -967.34M | -805.51M |
| Other liab | - | - | - | 79.96M | 77.48M |
| Other assets | - | - | - | 3.72M | 3.80M |
| Cash | 602.07M | 302.08M | 200.35M | 88.50M | 150.56M |
| Total current liabilities | 95.06M | 110.95M | 186.44M | 71.52M | 64.20M |
| Current deferred revenue | 44.44M | 65.97M | 150.06M | 31.56M | 37.10M |
| Net debt | -584.30M | -276.67M | -168.23M | -50.88M | -120.65M |
| Short term debt | 8.36M | 7.64M | 6.71M | 5.50M | 4.96M |
| Short long term debt total | 17.77M | 25.40M | 32.12M | 37.61M | 29.92M |
| Other stockholder equity | 228.37M | 156.45M | 129.24M | 119.44M | 87.98M |
| Property plant equipment | - | - | - | 17.28M | 22.27M |
| Total current assets | 614.81M | 320.39M | 235.37M | 98.54M | 162.56M |
| Net tangible assets | - | - | - | -37.22M | 40.37M |
| Net receivables | 1.28M | 1.42M | 21.09M | - | 0.00M |
| Inventory | - | - | 0.00M | - | - |
| Accounts payable | 15.70M | 16.26M | 12.84M | 16.91M | 7.28M |
| Accumulated other comprehensive income | -0.25M | -0.26M | -0.12M | -0.03M | 0.18M |
| Common stock total equity | - | - | - | 802.83M | 749.85M |
| Retained earnings total equity | - | - | - | -967.34M | -805.51M |
| Non currrent assets other | 0.02M | 3.81M | 0.16M | 3.72M | 3.80M |
| Non current assets total | 23.68M | 31.81M | 39.58M | 47.85M | 44.44M |
| Capital lease obligations | 17.77M | 25.40M | 32.12M | 37.61M | 29.92M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | - | -0.94M | -1.11M | -1.25M | -0.56M |
| Change to liabilities | - | - | - | 12.23M | -4.15M |
| Total cashflows from investing activities | -0.72M | -0.94M | -1.11M | -1.25M | -0.56M |
| Total cash from financing activities | 488.24M | 253.89M | 132.53M | 67.19M | 55.83M |
| Change to operating activities | - | - | - | - | 2.04M |
| Net income | -204.38M | -97.01M | -57.51M | -161.82M | -122.25M |
| Change in cash | 300.04M | 101.79M | 111.89M | -62.06M | -33.93M |
| Begin period cash flow | 302.08M | 204.05M | 92.16M | 154.22M | 188.15M |
| End period cash flow | 602.07M | 305.84M | 204.05M | 92.16M | 154.22M |
| Total cash from operating activities | -187.49M | -151.03M | -19.43M | -127.78M | -88.99M |
| Issuance of capital stock | 472.49M | 236.18M | 131.28M | 52.33M | 54.97M |
| Depreciation | 8.85M | 8.66M | 9.21M | 10.11M | 9.84M |
| Other cashflows from investing activities | -0.72M | -0.94M | - | 0.11M | - |
| Change to inventory | - | - | - | - | 2.04M |
| Change to account receivables | 0.15M | 19.66M | -21.09M | 0.00M | 30.00M |
| Sale purchase of stock | - | - | - | 66.08M | 55.83M |
| Other cashflows from financing activities | 488.24M | 17.71M | 1.26M | 14.86M | 0.86M |
| Change to netincome | - | - | - | 17.21M | 16.41M |
| Capital expenditures | 0.72M | 0.94M | 1.11M | 1.36M | 0.56M |
| Change receivables | - | - | - | - | 30.00M |
| Cash flows other operating | - | - | - | -1.97M | -16.49M |
| Cash and cash equivalents changes | - | - | - | -61.85M | -33.73M |
| Change in working capital | -16.94M | -75.82M | 19.08M | 6.72M | 7.01M |
| Stock based compensation | 24.97M | 13.14M | 9.79M | 17.19M | 16.41M |
| Other non cash items | 24.97M | -75.20M | -24.85M | 0.01M | 25.13M |
| Free cash flow | -187.49M | -151.96M | -20.55M | -129.14M | -89.55M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| WVE Wave Life Sciences Ltd |
-0.02 0.58% |
3.40 | - | - | 13.44 | 1.94 | 6.61 | -10.12 |
| NVO Novo Nordisk A/S |
-0.54 1.32% |
40.55 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-2.37 0.43% |
544.66 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
-2.77 0.29% |
956.64 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Wave Life Sciences, Inc., a clinical-stage biotechnology company, focuses on unlocking the potential of ribonucleic acid (RNA) medicines to transform human health. Its RNA medicines platform, PRISM, combines RNA medicine modalities, chemistry innovation, and deep insights in human genetics to deliver scientific breakthroughs that treat rare and common disorders. Its pipeline focuses on obesity (WVE-007), alpha-1 antitrypsin deficiency (AATD) (WVE-006), and PNPLA3 I148M liver disease (WVE-008) programs; and clinical programs for Duchenne muscular dystrophy and Huntington's disease, as well as various preclinical programs utilizing its RNA medicines platform. Wave Life Sciences, Inc. was founded in 2012 and is headquartered in Cambridge, Massachusetts.
733 Concord Avenue, Cambridge, MA, United States, 02138
617 949 2900
317
| Name | Title | Year Born |
|---|---|---|
| Dr. Paul B. Bolno M.B.A., M.D., MBA | Pres, CEO & Director | 1974 |
| Dr. Chandra Vargeese Ph.D. | Chief Technology Officer & Head of Platform Discovery Sciences | 1961 |
| Mr. Kyle B. Moran CFA | CFO & Principal Accounting Officer | 1971 |
| Kate Rausch | Head of Investor Relations | NA |
| Ms. Linda Rockett J.D. | Gen. Counsel | NA |
| Dr. Christopher Francis Ph.D. | Sr. VP of Corp. Devel. & Head of Emerging Areas | 1978 |
| Mr. Jonathan Rosin | Chief HR Officer | NA |
| Dr. Sridhar Vaddeboina Ph.D. | Sr. VP of Chemistry, Manufacturing & Controls | NA |
| Ms. Anne-Marie Li-Kwai-Cheung | Chief Devel. Officer | NA |
| Dr. Stephen L. Lake | Sr. VP & Head of Clinical Devel. | NA |
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