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Scancell Holdings plc, a clinical stage biopharmaceutical company, discovers and develops of immunotherapies for the treatment of cancer in the United Kingdom. Its product candidates include SCIB1/iSCIB1+ that is in Phase II for the treatment of melanoma; and SC134, an antibody for the treatment of small cell lung cancer. It also develops Modi-1, an active peptide immunotherapy that is in phase II clinical trials for the treatment of solid tumors, including renal, head and neck, ovarian and triple negative breast cancers; and Modi-2, which targets stress-induced post translational modifications, such as homocittrullination. In addition, the company provides GlyMab platform that generates various affinity tumour specific monoclonal antibodies (mAb) targeting glycans that are over-expressed on cancer cells; and AvidiMab, which romotes receptor clustering thereby improving immune signalling. Scancell Holdings plc was founded in 1996 and is based in Oxford, the United Kingdom.
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Scancell Holdings plc is a clinical-stage biotechnology company developing T-cell focused cancer immunotherapies using its ImmunoBody and Moditope platforms. Long-term growth may be driven by clinical trial progress, successful combinations with checkpoint inhibitors, and licensing or partnership deals to advance and commercialize candidates. Investors may find exposure to differentiated antigen-targeting approaches and potential for durable anti-tumor immune responses attractive.
Key risks include high clinical and regulatory failure risk, limited revenues and cash reserves requiring fundraising, execution challenges scaling manufacturing and development, and intense competition in immuno-oncology.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-04-30 | 2024-04-30 | 2023-04-30 | 2022-04-30 | 2021-04-30 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-04-30 | 2024-04-30 | 2023-04-30 | 2022-04-30 | 2021-04-30 |
| Income before tax | -15.30M | -14.30M | -14.30M | -3.77M | -16.80M |
| Net income | -12.27M | -11.94M | -11.94M | -2.06M | -15.48M |
| Selling general administrative | 4.79M | 5.02M | 5.02M | 4.79M | 3.35M |
| Gross profit | 4.47M | 4.75M | 4.75M | - | - |
| Reconciled depreciation | 0.88M | 0.97M | 0.90M | 0.74M | 0.25M |
| Ebit | -15.00M | -13.09M | - | -8.05M | -15.15M |
| Ebitda | -14.51M | -12.19M | - | -7.31M | -14.90M |
| Depreciation and amortization | 0.49M | 0.90M | - | 0.74M | 0.25M |
| Operating income | -15.00M | -11.92M | -11.92M | -13.30M | -8.83M |
| Other operating expenses | 19.71M | 17.19M | - | 13.30M | 8.83M |
| Interest expense | 1.38M | 1.09M | 1.22M | 2.88M | 1.65M |
| Tax provision | -3.03M | -3.26M | -2.37M | -1.70M | -1.33M |
| Interest income | 0.34M | 0.35M | 0.28M | 0.00M | 0.00M |
| Net interest income | -1.38M | -0.73M | -0.93M | 2.37M | -7.97M |
| Income tax expense | 3.03M | -2.37M | - | -1.70M | -1.33M |
| Total revenue | 4.71M | 5.27M | 5.27M | 0.00M | 0.00M |
| Total operating expenses | 19.47M | 16.67M | 17.19M | 13.30M | 8.83M |
| Cost of revenue | 0.24M | 0.53M | 0.53M | - | - |
| Total other income expense net | -0.30M | -2.38M | - | 9.53M | -7.97M |
| Net income from continuing ops | -12.27M | -5.86M | -11.94M | -2.06M | -15.48M |
| Net income applicable to common shares | - | - | - | -2.06M | -15.48M |
| Breakdown | 2025-04-30 | 2024-04-30 | 2023-04-30 | 2022-04-30 | 2021-04-30 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-04-30 | 2024-04-30 | 2023-04-30 | 2022-04-30 | 2021-04-30 |
| Total assets | 23.09M | 23.58M | 30.27M | 38.52M | 49.06M |
| Intangible assets | 1.62M | - | - | - | - |
| Other current assets | 3.73M | 1.20M | - | - | - |
| Total liab | 26.93M | 27.08M | 36.50M | 20.41M | 29.57M |
| Total stockholder equity | -3.83M | -3.50M | -6.23M | 18.11M | 19.48M |
| Other current liab | 10.05M | 2.72M | - | 0.34M | 0.06M |
| Common stock | 1.04M | 0.93M | - | 0.81M | 0.81M |
| Capital stock | 1.04M | 0.93M | 0.82M | 0.81M | 0.81M |
| Retained earnings | -91.42M | -84.19M | -74.36M | -49.12M | -47.05M |
| Other liab | - | - | - | 10.10M | 12.03M |
| Good will | - | - | 3.42M | 3.42M | 3.42M |
| Cash | 16.89M | 14.82M | 19.92M | 28.73M | 41.11M |
| Total current liabilities | 26.80M | 6.39M | 3.28M | 2.45M | 2.29M |
| Net debt | -0.63M | 5.05M | - | -20.55M | -25.66M |
| Short term debt | 16.14M | 2.03M | - | 0.32M | 0.21M |
| Short long term debt | 15.75M | 1.61M | - | - | - |
| Short long term debt total | 16.27M | 19.87M | - | 8.18M | 15.46M |
| Other stockholder equity | 82.40M | 79.75M | - | 66.41M | 65.72M |
| Property plant equipment | - | - | - | 2.74M | 0.97M |
| Total current assets | 20.62M | 21.87M | 24.61M | 32.36M | 44.67M |
| Net tangible assets | - | - | - | 14.70M | 16.07M |
| Net receivables | 3.18M | 5.85M | 0.54M | 3.19M | 2.84M |
| Long term debt | 0.00M | 17.37M | 18.48M | 7.01M | 15.18M |
| Accounts payable | 0.61M | 1.46M | 2.97M | 2.14M | 2.09M |
| Accumulated other comprehensive income | 4.14M | 3.48M | - | - | - |
| Non current assets total | 2.47M | 1.71M | 5.66M | 6.16M | 4.39M |
| Capital lease obligations | 0.51M | 0.89M | 1.05M | 1.17M | 0.27M |
| Breakdown | 2025-04-30 | 2024-04-30 | 2023-04-30 | 2022-04-30 | 2021-04-30 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-04-30 | 2024-04-30 | 2023-04-30 | 2022-04-30 | 2021-04-30 |
| Investments | -1.20M | 0.18M | 0.08M | -1.26M | -0.74M |
| Change to liabilities | - | - | - | 0.05M | 1.05M |
| Total cashflows from investing activities | -1.20M | 0.18M | - | -1.26M | -0.74M |
| Net borrowings | -0.45M | 0.00M | - | -0.39M | 23.35M |
| Total cash from financing activities | 9.69M | 10.39M | - | -0.93M | 46.08M |
| Net income | -12.27M | -9.12M | -11.94M | -3.77M | -16.80M |
| Change in cash | 2.08M | -5.10M | -8.80M | -12.38M | 37.53M |
| Begin period cash flow | 14.82M | 19.92M | 28.73M | 41.11M | 3.58M |
| End period cash flow | 16.89M | 14.82M | 19.92M | 28.73M | 41.11M |
| Total cash from operating activities | -6.40M | -15.66M | -8.14M | -10.19M | -7.80M |
| Issuance of capital stock | 11.28M | 11.99M | 0.17M | 0.00M | 24.14M |
| Depreciation | 0.88M | 0.97M | 0.90M | 0.74M | 0.25M |
| Other cashflows from investing activities | -1.19M | 0.35M | - | 0.00M | 0.00M |
| Change to account receivables | 0.75M | -0.84M | - | 0.32M | -0.60M |
| Other cashflows from financing activities | 10.54M | -1.24M | - | -1.26M | 21.94M |
| Change to netincome | - | - | - | -9.24M | 6.98M |
| Capital expenditures | 0.01M | 0.18M | 0.20M | 1.27M | 0.74M |
| Change in working capital | 0.75M | -0.71M | 0.94M | 0.37M | 0.45M |
| Stock based compensation | 1.36M | 0.66M | 0.73M | 0.69M | 0.33M |
| Other non cash items | 2.89M | -7.46M | 2.38M | -8.23M | 7.97M |
| Free cash flow | -6.41M | -15.84M | -8.34M | -11.46M | -8.55M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| NVO Novo Nordisk A/S |
0.01 0.02% |
40.31 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
4.59 0.85% |
547.09 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
1.45 0.16% |
904.35 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
900.30 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Scancell Holdings plc, a clinical stage biopharmaceutical company, discovers and develops of immunotherapies for the treatment of cancer in the United Kingdom. Its product candidates include SCIB1/iSCIB1+ that is in Phase II for the treatment of melanoma; and SC134, an antibody for the treatment of small cell lung cancer. It also develops Modi-1, an active peptide immunotherapy that is in phase II clinical trials for the treatment of solid tumors, including renal, head and neck, ovarian and triple negative breast cancers; and Modi-2, which targets stress-induced post translational modifications, such as homocittrullination. In addition, the company provides GlyMab platform that generates various affinity tumour specific monoclonal antibodies (mAb) targeting glycans that are over-expressed on cancer cells; and AvidiMab, which romotes receptor clustering thereby improving immune signalling. Scancell Holdings plc was founded in 1996 and is based in Oxford, the United Kingdom.
| Name | Title | Year Born |
|---|---|---|
| Prof. Lindy Gillian Durrant Ph.D. | Founder, CEO, Chief Scientific Officer & Director | NA |
| Dr. Sally Elizabeth Adams | Chief Devel. Officer & Director | 1961 |
| Mr. Keith Green | Director of Fin. & Admin. and Company Sec. | NA |
| Dr. Samantha Paston Ph.D. | Head of Translational Research | NA |
| Dr. Adrian Parry Ph.D. | Head of Manufacturing | NA |
| Ms. Akua Asare | Head of Quality | NA |
| Mr. Fayaz Master | Head of Clinical Operations | NA |
| Dr. Phillip John L'Huillier MBA, Ph.D. | CEO & Director | 1962 |
| Prof. Lindy Gillian Durrant Ph.D. | Chief Scientific Officer, Director & Founder | 1957 |
| Mr. David Schilansky | Interim Chief Financial Officer | 1975 |
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