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Medicenna Therapeutics Corp., a clinical-stage immunotherapy company, engages in the development and commercialization of Superkines and empowered Superkines for the treatment of cancer, inflammation, and immune-mediated diseases. It develops bizaxofusp, an interleukin- 4 (IL-4) targeted therapy for the treatment of recurrent glioblastoma. The company also develops MDNA11, a long-acting interleukin-2 (IL-2) to activate anti-cancer immune cells over immunosuppressive Tregs; MDNA209, an IL-2/IL-15 antagonist for autoimmune diseases, such as multiple sclerosis and graft versus host diseases; MDNA413, a dual IL-4/IL-13 antagonist to treat cancer immunotherapies; MDNA113, a tumor-targeting and activatable masked anti-PD-1-IL-2 BiSKITTM for cancer; and MDNA132, an IL-13 Superkine for various tumors. Medicenna Therapeutics Corp. is headquartered in Toronto, Canada.
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Medicenna Therapeutics is a clinical-stage biotech developing engineered cytokine therapies for cancer and inflammatory diseases, including an IL-2–based program intended to boost anti-tumor immune cells with less toxicity. Long-term growth may be driven by clinical advancement of its platform, collaborations, and successful combination use with checkpoint inhibitors.
Key risks include clinical and regulatory failure, absence of approved products requiring further financing that could dilute shareholders, and intense competition in immuno-oncology that investors should monitor.
Note: The summary and risk score provided above is created by AI and should not be construed as a recommendation of Kalkine.
| Breakdown | 2025-03-31 | 2024-03-31 | 2023-03-31 | 2022-03-31 | 2021-03-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-03-31 | 2024-03-31 | 2023-03-31 | 2022-03-31 | 2021-03-31 |
| Income before tax | -13.03M | -25.47M | -10.05M | -22.58M | -17.29M |
| Net income | -11.80M | -25.47M | -10.05M | -22.65M | -17.39M |
| Selling general administrative | 5.91M | 7.87M | 6.99M | 7.72M | 6.49M |
| Selling and marketing expenses | - | 0.01M | - | - | - |
| Gross profit | -0.06M | -0.01M | - | - | - |
| Reconciled depreciation | 0.05M | 0.00M | 0.00M | 0.04M | 0.04M |
| Ebit | -13.03M | -18.68M | -16.30M | -22.30M | -17.19M |
| Ebitda | -12.97M | -18.67M | -16.30M | -22.26M | -17.15M |
| Depreciation and amortization | 0.06M | 0.01M | - | 0.04M | 0.04M |
| Operating income | -21.63M | -19.66M | -16.30M | -22.30M | -17.19M |
| Other operating expenses | 21.63M | 19.66M | - | 22.47M | 17.39M |
| Interest expense | - | - | - | 0.07M | 0.00M |
| Interest income | 8.60M | 1.20M | 6.25M | 0.07M | 0.11M |
| Net interest income | 1.35M | 1.20M | 0.91M | 0.07M | 0.31M |
| Income tax expense | -1.23M | - | - | 0.07M | 0.10M |
| Total revenue | 0.00M | 0.00M | 0.00M | 0.00M | 0.00M |
| Total operating expenses | 21.58M | 19.66M | 16.30M | 22.47M | 17.39M |
| Cost of revenue | 0.06M | 0.01M | - | - | - |
| Total other income expense net | 8.60M | -5.80M | 5.34M | -0.28M | -0.10M |
| Net income from continuing ops | -11.80M | -25.47M | -10.05M | -22.58M | -17.29M |
| Net income applicable to common shares | -11.80M | -25.47M | -10.05M | -22.58M | -17.29M |
| Breakdown | 2025-03-31 | 2024-03-31 | 2023-03-31 | 2022-03-31 | 2021-03-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-03-31 | 2024-03-31 | 2023-03-31 | 2022-03-31 | 2021-03-31 |
| Total assets | 28.38M | 19.13M | 36.45M | 23.46M | 42.25M |
| Intangible assets | 0.05M | 0.06M | 0.06M | 0.07M | 0.07M |
| Other current assets | - | 0.93M | - | 1.55M | - |
| Total liab | 9.29M | 13.94M | 6.96M | 2.62M | 4.11M |
| Total stockholder equity | 19.09M | 5.19M | 29.49M | 20.84M | 38.15M |
| Other current liab | - | 0.79M | 3.16M | 0.95M | 1.83M |
| Common stock | 116.30M | 100.92M | 100.92M | 83.67M | 79.59M |
| Capital stock | 116.30M | 100.92M | 100.92M | 83.67M | 79.59M |
| Retained earnings | -118.25M | -106.45M | -80.98M | -70.93M | -48.36M |
| Other assets | - | 0.00M | - | - | - |
| Cash | 24.84M | 16.98M | 33.60M | 20.54M | 30.38M |
| Cash and equivalents | 24.84M | - | 33.60M | 20.54M | 30.38M |
| Total current liabilities | 4.43M | 2.86M | 6.96M | 2.62M | 4.11M |
| Net debt | - | -16.98M | - | -20.54M | -30.34M |
| Short term debt | 0.00M | - | 0.00M | 0.00M | 0.03M |
| Short long term debt total | - | - | - | - | 0.03M |
| Other stockholder equity | 0.00M | 10.70M | 0.06M | 7.93M | 6.68M |
| Property plant equipment | 0.16M | - | - | 0.00M | 0.03M |
| Total current assets | 28.17M | 19.08M | 36.38M | 23.39M | 42.15M |
| Net tangible assets | - | - | 29.43M | 20.77M | 38.07M |
| Short term investments | - | - | - | 0.00M | 10.01M |
| Net receivables | - | 1.16M | 0.85M | 1.31M | 0.41M |
| Accounts payable | 2.70M | 2.07M | 1.62M | 1.67M | 2.25M |
| Accumulated other comprehensive income | - | 0.02M | - | 0.17M | 0.23M |
| Non currrent assets other | - | -0.00M | - | - | - |
| Non current assets total | 0.21M | 0.06M | 0.06M | 0.07M | 0.10M |
| Capital lease obligations | 0.17M | - | - | 0.00M | 0.03M |
| Long term debt total | 0.12M | - | 0.00M | 0.00M | 0.00M |
| Breakdown | 2025-03-31 | 2024-03-31 | 2023-03-31 | 2022-03-31 | 2021-03-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-03-31 | 2024-03-31 | 2023-03-31 | 2022-03-31 | 2021-03-31 |
| Investments | -0.03M | 0.00M | 0.00M | 10.05M | 5.01M |
| Change to liabilities | - | - | 1.18M | -1.45M | 2.29M |
| Total cashflows from investing activities | -0.03M | - | 0.00M | 10.05M | 5.01M |
| Net borrowings | -0.02M | 0.00M | - | -0.04M | -0.04M |
| Total cash from financing activities | 23.49M | 0.00M | 24.76M | 3.88M | 18.26M |
| Net income | -11.80M | -25.47M | -10.05M | -22.58M | -17.29M |
| Change in cash | 7.86M | -16.61M | 13.06M | -9.84M | 7.68M |
| Begin period cash flow | 16.98M | 33.60M | 20.54M | 30.38M | 22.70M |
| End period cash flow | 24.84M | 16.98M | 33.60M | 20.54M | 30.38M |
| Total cash from operating activities | -16.49M | -16.26M | -12.66M | -23.58M | -15.31M |
| Issuance of capital stock | 19.71M | 0.00M | 24.76M | 3.51M | 11.41M |
| Depreciation | 0.05M | 0.00M | 0.00M | 0.04M | 0.04M |
| Other cashflows from investing activities | - | - | 0.00M | 10.05M | 5.01M |
| Change to account receivables | -0.21M | 1.68M | 1.23M | -0.39M | -1.61M |
| Sale purchase of stock | 23.51M | 0.00M | 24.76M | 3.92M | 18.30M |
| Other cashflows from financing activities | 3.80M | - | - | 0.41M | 6.88M |
| Change to netincome | - | - | -5.02M | 0.80M | 1.26M |
| Capital expenditures | 0.03M | 0.00M | 0.00M | 0.00M | 0.00M |
| Change in working capital | 1.31M | 0.74M | 2.41M | -1.84M | 0.68M |
| Stock based compensation | 2.21M | 1.21M | 1.37M | 1.42M | 1.01M |
| Other non cash items | -8.27M | 7.25M | -0.97M | -0.62M | 0.25M |
| Free cash flow | -16.52M | -16.26M | -12.66M | -23.58M | -15.31M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(CAD) |
Price
(CAD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|
| MDNA Medicenna Therapeutics Corp |
0.02 4.82% |
0.43 | - | 232.56 | - | 8.06 | -6.11 |
| EPRX Eupraxia Pharmaceuticals Inc |
-0.17 1.76% |
9.48 | - | - | - | 8.45 | -3.88 |
| FRX Fennec Pharmaceuticals Inc |
0.20 1.35% |
14.99 | - | 21.01 | 6.95 | 6.35 | 20.27 |
| MSCL Satellos Bioscience Inc. |
- -% |
9.00 | - | - | - | 5.85 | 6.47 |
| HBP Helix BioPharma Corp. |
-0.10 9.80% |
0.92 | - | 3.87 | 4263.36 | 9.74 | -6.36 |
Medicenna Therapeutics Corp., a clinical-stage immunotherapy company, engages in the development and commercialization of Superkines and empowered Superkines for the treatment of cancer, inflammation, and immune-mediated diseases. It develops bizaxofusp, an interleukin- 4 (IL-4) targeted therapy for the treatment of recurrent glioblastoma. The company also develops MDNA11, a long-acting interleukin-2 (IL-2) to activate anti-cancer immune cells over immunosuppressive Tregs; MDNA209, an IL-2/IL-15 antagonist for autoimmune diseases, such as multiple sclerosis and graft versus host diseases; MDNA413, a dual IL-4/IL-13 antagonist to treat cancer immunotherapies; MDNA113, a tumor-targeting and activatable masked anti-PD-1-IL-2 BiSKITTM for cancer; and MDNA132, an IL-13 Superkine for various tumors. Medicenna Therapeutics Corp. is headquartered in Toronto, Canada.
| Name | Title | Year Born |
|---|---|---|
| Dr. Fahar Merchant Ph.D. | Founder, Chairman, Pres & CEO | 1957 |
| Ms. Rosemina Merchant B.Sc., M.E.Sc | Founder, Chief Devel. Officer & Director | 1957 |
| Ms. Elizabeth Williams C.A., CPA, CA, CPA | CFO & Corp. Sec. | 1978 |
| Dr. Martin Bexon M.D., MBBS | Acting Chief Medical Officer & Head of Clinical Devel. | NA |
| Dr. Samuel R. Denmeade M.D. | Scientific Advisor | NA |
| Dr. Fahar Merchant Ph.D. | Founder, Chairman, President & CEO | 1957 |
| Ms. Rosemina Merchant B.Sc., M.E.Sc | Founder & Chief Development Officer | 1957 |
| Mr. David Hyman CA, CBV | Chief Financial Officer | 1973 |
| Dr. Nageatte Ibrahim M.D. | Chief Medical Officer | NA |
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